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Adaptive (Specific) Immunity
The immune system's second line of defense; involves a targeted response with memory for specific
Humoral Immunity
Antibody-mediated immunity; driven by B cells and antibodies that target pathogens in body fluids.
B Lymphocyte (B Cell)
A type of white blood cell that, when activated, differentiates into antibody-producing plasma cells and memory cells.
Antigen
A molecule (often foreign) that can trigger an adaptive immune response by binding to specific receptors.
B Cell Receptor (BCR)
The membrane-bound antibody on a B cell's surface that binds a specific antigen.
Clonal Selection
The process where a lymphocyte (B or T cell) that binds its specific antigen is stimulated to proliferate into a clone of identical cells.
Plasma Cell
The short-lived, effector cell derived from a B cell; secretes large amounts of a specific antibody.
Memory B Cell
A long-lived B cell clone that remains after an infection, providing immunological memory for a faster secondary response
Antibody (Immunoglobulin)
A Y-shaped protein secreted by plasma cells that binds specifically to a unique antigen.
Neutralization
An antibody function where it blocks the binding site of a virus or toxin, preventing it from attaching to host cells.
Opsonization
The process where antibodies coat a pathogen, marking it for engulfment and destruction by phagocytes.
Complement System
A group of plasma proteins that, when activated (often by antibodies), enhance inflammation, opsonization, and cell lysis.
Immunological Memory
The adaptive immune system's ability to "remember" previous pathogens and mount a stronger, faster response upon re-exposure.
Vaccine
A biological preparation that provides active acquired immunity to a particular infectious disease by stimulating immune memory.
Active Immunity
Immunity that develops from the production of your own antibodies and memory cells after exposure to an antigen.