Compounding Midterm

a.

(before)

a., aur

(ear)

a.d.

(right ear)

a.l.

(left ear)

aa.

(of each)

a.c.

(before meals)

ad

(to, up to)

add.

(added, to be added)

(by adding)

ad lib.

(at pleasure)

adm.

(apply)

agit

(shake)

alb

(white)

alt.hor.

(every other hour)

A.M.

(before noon)

ampl.

(large)

ampul.

(ampulm ampule)

aq.

(aqueous)

au.bull

(boiling water)

aq. dest.

(distilled water)

aq. ferv.

(hot water)

aq. frig.

(cold water)

a.

(twice)

a.t.c.

around the clock

ben.

(well)

bib.

(drink)

b.i.d.

(twice a day)

c

(with)

C

(a hundred)

cap.

(let the patient take)

caps.

(a capsule)

chart.

(paper, a powder in a paper)

chartul.

(a small paper)

chch. amp. OR coch. mag.

(a tablespoonful)

coch. med.

(a dessertspoonful)

coch. mod.

(a dessertspoonful)

coch. parv.

(a teaspoonful)

collun.

(a nose wash)

collut.

(a mouth wash)

collyr.

(an eye wash)

cong.

(a gallon)

consperg.

(to dust, sprinkle)

d.

(right)

(a day)

(a dose)

da

(give)

de d. in d.

(from day to day)

dent., d.

(let be given, give)

det.

(let it be given)

dieb. alt.

(every other day)

disp.

(dispense)

dis.

divide

div. in par. aeq.

(divide in equal parts)

d. t. d.

(give such doses)

dulc.

(sweet)

e. m. p.

(after the manner prescribed)

et

(and)

ext.

(an extract)

f., ft

(make, let be made)

filt.

(fluid)

flav.

(yellow)

fldexte

(fluid extract)

fort.

(strong)

frig.

(cold)

garg.

(a gargle)

Gm.

(gram)

gr.

(grain)

gran.

(granulated)

gtt.

(a drop)

h. s.

(at bedtime)

i. c.

(between meals)

kal.

(potassium)

laev.

(left)

lb.

(pound)

lev.

(light)

liq

(a liquor, a solution)

lot.

lotion

m.

(in the morning)

(send)

M.

(mix)

mag.

(large)

m. dict.

(as directed)

min.

(minim)

mist.

(mixture)

The beyond use date is the date after which the compounded product should NOT be used. What is the BUD for a water containing topical formulation stored in a tight light-resistant container?

14 days

30 days

3 months

6 months

30 days

A solution is a solute dissolved in a solvent.

Fill in the blank.

____________ are sweet hydroalcoholic solutions used for drugs that would be insoluble in a purely aqueous formulation. Hydroalcohol is a mixture of alcohol and water.

Syrups

Elixirs

Tinctures

Spirits

Elixirs

Which of the following is a true statement pertaining to pharmaceutical solutions?

Methyl alcohols can cause paralysis of the central nervous system and are irritating to the skin

Butyl and amyl alcohols are irritating

Ketones can paralyze the central nervous system and irritate mucous membranes

DMO is an approved solvent for internal use

Butyl and amyl alcohols are irritating

Calculate the factor for the preparation of 90 ml from the following formula.

Rx

Sucrose 850 grams

Purified Water, qs 1000 ml

0.09

90 ml/1000 ml

Based on the lab handout, how many milliliters of calamine lotion will we prepare today. ONLY input the number. No units.

90

Pharmaceutical suspensions are _____________ dispersions consisting of a finely divided insoluble solid that is evenly dispersed in a liquid.

Coarse

Flocculating

Dissolved

Smooth

Coarse

The disadvantages of formulating a suspension can be minimized by carefully formulating the suspension and by shaking the suspension before administering each dose.

Which of the following is an advantage of a pharmaceutical suspension? Select all that apply.

Drugs in suspension are chemically more stable than drugs in solution

Unpleasant tastes can be masked

Most cost effective dosage form

Possible dose irregularity

Drugs in suspension are chemically more stable than drugs in solution

Unpleasant tastes can be masked

Based on the lab handout, what is bentonite magma diluted with?

Purified Water

Calamine

Calcium Chloride Solution

Zinc Oxide

Calcium Chloride Solution

Calculate the Acacia Powder needed to prepare a 60 ml prescription based off the USP formula below. Report to the tenths place. NO UNITS

Rx

Liquid Petroleum 500 ml

Acacia Powder 125 grams

Syrup U.S.P. 100 ml

Purified Water q.s. ad to 1000 ml

7.5

125 grams/1000 = 0.125g

0.125g x 60 = 7.5g

The hydrophile - lipophile balance numbers are determined experimentally for the different surfactants. If a surfactant has a low HLB number, it means that there are few hydrophilic groups on the molecule and it will have more of a lipophilic character. A surfactant with a HLB between 3 - 8 are used for which of the following?

Antifoaming agents

Emulsifying agent for w/o emulsions

Wetting agents

Emulsifying agent for o/w emulsions

Emulsifying agent for w/o emulsions

Emulsions are thermodynamically unstable and tend to separate into two distinct phases over time. The separation can be a sign of instability. How many levels of instability have been documented for emulsions?

1

2

3

4

3

Based on the Rx below, identify the emulsifying agent.

Rx

Liquid Petroleum 500 ml

Acacia Powder 125 grams

Syrup U.S.P. 100 ml

Purified Water q.s. ad to 1000 ml

Mineral Oil

Acacia Powder

Simple Syrup

Liquid Petroleum

Acacia Powder

Various dosage forms are utilized to deliver drugs to the eyes. Ophthalmic formulations are compounded using the same standards as intravenous formulations.

Which of the following is the white portion of the eye?

Eyelids

Iris

Pupil

Sclera

Sclera

_________________ is defined as the absence of viable microbial contamination. This factor is a requirement of ALL ophthalmic formulations.

Sterility

Solubility

Sanitary

Stability

Sterility

Formulating a ophthalmic product at the ideal pH is not always possible due to drug solubility, chemical stability or therapeutic activity. Ophthalmic solutions are generally buffered in a pH range of 4.5 - 11.5 but the useful range to prevent corneal damage is _________________.

12 - 14

5 - 9

1.7 - 2.3

6.5 - 8.5

6.5 - 8.5

How many grams of NaCl is needed to make a 90 ml solution isotonic? Report to the hundredths place. NO UNITS

0.81

What is the meaning of the latin abbreviation d.t.d?

After the manner prescribed

Give such doses

Let it be given

Divide in equal parts

Give such doses

What is the meaning of the latin word dies?

Dispensel

Divide |

A day

A dose

A day

What latin abbreviation means large?

mag.

laev.

lev.

|m.

mag.

What latin term means before?

Ad

Bis

Bibe

Ante

Ad