LEC RH BLOOD GROUP

004

isbt of rh blood group

chromosome 1

chromosome number of rh blood group

levine and stetson

who discovered the novel antibody and antigen and HDFN

landsteiner and wiener

who discovered antibodies from guinea pigs with blood from rhesus macaque monkeys

anti d

antisera in rh typing and a monoclonal antibody that contains a blend of igg and igm class

igm

allows direct agglutination in immediate spin

igg

allows weak d typing

weak d

weakened expression d antigen only detectable in IAT

weak d

D Ags expressed appear to be complete but fewer in number

rhd gene

where do mutations occur that causes changes in the amino acids in weak d

partial d or d mosaic

Missing or defective one or more epitopes of the total D antigen

alloAb

this may be produced in partial d due to missing fraction

del

RBCs possess an extremely low number of D antigen sites that most reagent anti-D are unable to detect

r0har or dhar

results from a hybrid gene RHCE-RHD-RHCE

crawford or cecf

Results from a specific amino acid change in the RhCE gene