FENTANYL CITRATE

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Last updated 11:03 AM on 8/8/25
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8 Terms

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GENERIC NAME

Sublimaze

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CLASS

Opioid analgesic

Synthetic opioid

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MECHANISM OF ACTION

Fentanyl is a powerful opioid pain medication that works by blocking pain signals in the brain and spinal cord

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INDICATION

Moderate to severe pain

Sedation for procedures

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CONTRAINDICATIONS

Known tolerance to the drug

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ADVERSE REACTIONS

Respiratory depression

Apnea

Rigidity

Bradycardia

Respiratory arrest

Circulatory depression

Cardiac arrest

Hypertension

Hypotension

Dizziness

Blurred vision

Nausea

Emesis

Laryngospasm

Chest wall rigidity

Diaphoresis

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DOSAGE - ADULT

1 mcg/kg. to max. 150 mcg. slow IV push

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DURATION OF ACTION

Onset: The onset of action of fentanyl is almost immediate when the drug is given intravenously; however, the maximal analgesic and respiratory depressant effect may not be noted for several minutes.

Peak effect: The peak respiratory depressant effect of a single intravenous dose of fentanyl citrate is noted as 5 to 15 minutes following injection

Duration: The usual duration of action of the analgesic effect is 30 to 60 minutes after a single intravenous dose of up to 100 mcg.