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GENERIC NAME
Sublimaze
CLASS
Opioid analgesic
Synthetic opioid
MECHANISM OF ACTION
Fentanyl is a powerful opioid pain medication that works by blocking pain signals in the brain and spinal cord
INDICATION
Moderate to severe pain
Sedation for procedures
CONTRAINDICATIONS
Known tolerance to the drug
ADVERSE REACTIONS
Respiratory depression
Apnea
Rigidity
Bradycardia
Respiratory arrest
Circulatory depression
Cardiac arrest
Hypertension
Hypotension
Dizziness
Blurred vision
Nausea
Emesis
Laryngospasm
Chest wall rigidity
Diaphoresis
DOSAGE - ADULT
1 mcg/kg. to max. 150 mcg. slow IV push
DURATION OF ACTION
Onset: The onset of action of fentanyl is almost immediate when the drug is given intravenously; however, the maximal analgesic and respiratory depressant effect may not be noted for several minutes.
Peak effect: The peak respiratory depressant effect of a single intravenous dose of fentanyl citrate is noted as 5 to 15 minutes following injection
Duration: The usual duration of action of the analgesic effect is 30 to 60 minutes after a single intravenous dose of up to 100 mcg.