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These flashcards cover key vocabulary and concepts related to toxicology and reproduction in various species, particularly focusing on endocrine disruptors, reproductive strategies in birds, sharks, and fish.
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Endocrine Disrupting Chemicals (EDCs)
Substances causing adverse health effects by disturbing hormone production or activity.
Agonist
A substance that mimics hormones and activates their receptors.
Antagonist
A substance that binds to receptors but does not activate the signaling pathway.
Non-monotonic Dose Response Curve
A graph showing that effects do not consistently increase or decrease with dose.
Examples of EDCs
Includes dioxins, phthalates, PFAS, bisphenol, found in various products.
Exposure routes for EDCs
EDCs can enter the body through breathing, eating, drinking, or touching.
Cocktail effect
Substances in mixtures having different effects than individually.
Heavy metal contaminants
Toxic elements like mercury, lead, cadmium, and arsenic affecting health.
Mercury sources
Methyl mercury from seafood; ethyl mercury from vaccines.
Lead exposure
Inhalation of contaminated air; ingestion via lead pipes or paint.
Cadmium sources
Found in cigarette smoke and certain vegetables.
Arsenic contamination
Presence in contaminated water supplies.
Effects of heavy metals on males
Disruption of testis barrier and decreased testosterone due to oxidative stress.
Effects of heavy metals on females
Decreased levels of sex hormones like GnRH, FSH, LH, and reduced ovarian function.
Ovulatory cycle of hens
Follicle growth stimulated by FSH; ovulation triggered by an LH surge.
Estrogen role in hens
Stimulates albumen synthesis and yolk protein development in follicles.
Oviposition mechanics
Contraction of shell gland stimulated by posterior pituitary secretions.
Timing of egg laying in hens
Eggs are ovulated 6 hours after an LH surge and laid 26.5 hours later.
Estradiol's role in LH surge
Rising estradiol levels stimulate the LH surge necessary for ovulation.
Testicular regression in seasonal breeders
Occurs in non-breeding season leading to reduced reproductive function.
Testosterone effects in male birds
Regulates song, aggression, and sexual displays.
Sperm storage in female birds
Sperm can survive in utero-vaginal junction folds for 2-15 weeks.
Determinacy in egg laying
Fixed clutch size, unaffected by environmental changes.
Indeterminacy in egg laying
Variable clutch size, responsive to environmental cues.
Altricial young
Hatch helpless, featherless, and with closed eyes.
Precocial young
Hatch with open eyes and down feathers; can move shortly after hatching.
Components of the egg
Yolk, albumen, shell membranes, and shell serving protective functions.
Amnion
Membrane surrounding the embryo that secretes amniotic fluid.
Chorion
Protective membrane surrounding all embryonic structures.
Allantois
Membrane involved in respiration and excretion, growing larger with embryo.
GnRH in males
Increases in late fall to stimulate testis size for breeding.
Melatonin's role in reproduction
Regulates reproductive cycles based on daylength.
Thyroid hormones in reproduction
Increase TSH, T4, and T3 with increasing daylength, activating GnRH.
Photostimulation
Occurs with increased daylength, stimulating reproductive hormones.
Photorefractoriness
Inhibits reproductive system in response to long photoperiods.
Photosensitivity
Resets reproductive cycles during extended short photoperiods.
Prolactin in birds
Important for nesting and parental behavior.
Sharks' reproductive cycle
Stages include immature females; breeding frequency may vary.
Shark reproductive lifespan
Slow to mature, with gestation longer than 12 months.
Oviparity in sharks
Lay eggs in ocean; no care for eggs afterward.
Viviparity in sharks
Live birth with developing young nourished through placenta.
Ovoviviparity in sharks
Eggs hatch inside female's body with no placenta.
Neuroendocrine regulation in sharks
Involves GnRHI and GnRHII for reproductive cycles.
Fertilization methods
Oviparous, ovoviviparous, viviparous.
Fish reproductive strategies
Dioecism and hermaphroditism, influencing mating behavior.
Mating partnerships in fish
Monogamy, polygyny, polyandry, and polygynandry.
Types of fish spawning
Pelagic and benthic, affecting egg survival strategies.