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what is Osteoporosis?
-Loss of bone mass
- Increased bone fragility
-Increased risk of fracture
( a Metabolic skeletal bone disorder)
what is the sequence of the disease process during Osteoporosis?
bone remodeling --> bone loss --> bone replacement--> reduced bone mineral density.
what population will have a bone fracture due to osteoporosis?
half of all women and men over the age of 50.
when bone resorption outpaces bone replacement... what can happen ?
bone loss and osteoporosis occur
Bone remodeling is affected by:
-Vitamin D
-Calcium levels
- Stress on bones caused by gravity and muscle action
-Tobacco smoking
-Alcohol consumption
-Hormones ( low in estrogen and Testosterone)
what is Cathepsin K ?
a product of osteoclasts that causes a breakdown of bone
what are the types of Osteoporosis (primary) ?
Primary:
type 1: associated with menopause
-linked to estrogen deficiency resulting in increased calcium reabsorption from bone
Type 2 - associated with decrease in bone formation that accompanies the aging process
- results from kidneys losing ability to process vitamin D--> decreased Calcium absorption
what is the "secondary" causes of Osteoporosis?
Result of disease process, deficiency, or effect of drug i.e. hyperparathyroidism
what are the Unmodifiable risk factors of Osteoporosis?
-Family history
-Age and sex
-Ethnicity
-Previous fractures
-Menopause
-Hysterectomy
- Other chronic disease
what are Modifiable risk factors ?
-poor nutrition
-Body weight
-Substance abuse
-Smoking
-Sedentary lifestyle
what are the common Clinical Manifestations of osteoporosis ?
Fractures, back pain, loss of height, stooped posture
what are the " fragility fracture" associated with osteoporosis
-common early manifestation
- Wrist, hip, and vertebrae
what can vertebral fracture cause ?
-Loss of height, back pain, functional limitations, spinal deformity
Causes dorsal kyphosis and cervical lordosis
what can hip fractures cause ?
Pain in the hip or groin, local swelling, bruising
what are the Diagnostic testing for osteoporosis?
DEXA and FRAX -->(fracture risk assessment tool)
what are management methods for Activity for osteoporosis?
Physical therapy & occupational therapy
what are the dietary methods for osteoporosis ?
-Healthy diet rich in calcium and vitamin D
- Limit intake of foods that affect bone strength like Caffeine and alcohol
what are Pharmacologic therapy methods?
Antiresorptive treatment
-Bisphosphonates, RANKL inhibitors, selective estrogen receptor modulators (SERMs)
- Anabolic tx
- Calcium and vitamin D supplements
- Calcitonin hormones
to block action of PTH
- Estrogen derivative drugs
-Parathyroid hormone analogs
what are the lifespan considerations in children ? ( think chronic issues )
-Diagnosed with spina bifida or cerebral palsy
- Those with Turner syndrome, growth hormone deficiency, osteogenesis imperfecta, juvenile rheumatoid arthritis, diabetes
what are the lifespan considerations in children ? ( think immobilization issues )
by casting or bracing
what are the lifespan considerations in children ? ( think sport issues )
-children who are very lean
-Adolescent female athletes at risk for female athlete triad -->
( Low bone mass• Disordered eating• Amenorrhea)
lifespan considerations for pregnancy: what factors can cause lost of bone mass ?
-fetus draws calcium from the mother's bone (only if the mother's diet is deficient in calcium)
- breastfeeding
lifespan considerations for pregnancy: "If a pregnant women has lost of bone mass, she will continue the same symptoms after pregnancy ? "
True or false ?
False. usually restored after few months
Lifespan considerations in older adults: cause an increase risk of ____?
fracture
what are other symptoms of old age that increase the risk of fractures ?
-Visual impairment
-Loss of balance
-Neuromuscular dysfunction
-Dementia
-Immobilization
-Use of sleeping pills
what are Prevention strategies of osteoporsis ?
-Adequate nutrition
-Weight-bearing and muscle-strengthening exercises
-Lifestyle modification: no smoking, weight reduction
- Medication and Supplements: bisphosphonate, hormone replacement
therapy, Calcium and vitamin K supplements
Fall and injury prevention
what is Degenerative Joint Disease (JDJ)
gradual deterioration of cartilage in the joints leading to pain, stiffness and reduced joint function
what is the most common form of arthritis?
Osteoarthritis
what happens to the joints in Osteoarthritis?
-Develops as wear, tear breaks down cartilage in joint
-Causes bone to rub on bone
OA the most common cause of disability for older adults? Y/N?
Yes
what does cartilage do for the joints ?
allows them to glide over each other without friction
Absorbs shock from physical movement
As a person ages, cartilage starts to break down, becomes rough, wears away.... what can happen ?
allows bone to rub on bone
what bones are usually effected by OA?
-Weight-bearing joints of hips, knees
-Digits of hand, big toe
-Cervical and lumbar spine
Does OA have an actually cause?
No. Believed to be caused by mechanical, molecular factors
what does the term "Localized OA" mean
effecting 1 or 2 joints
what does the term " Generalized OA" mean
effecting greater than or equal to 3 joints
what is the Secondary cause of OA ?
-Caused by underlying condition
-Injury
-Congenital malformation
-Metabolic, endocrine, or neuropathic disease
What are the risk factors for OA?
older age, sex, obesity, certain medical conditions, Fx
60% of people with OA are _____
women
where is OA typically seen in males?
hips, knees, and spine
where is OA typically seen in Females?
hipes, knees, hands
what are the specific medical conditions for OA ?
-Malformed joints or defective cartilage
-Diabetes, hypothyroid, gout, Paget disease
-Joint injuries from sports, accidents, repetitive use.
individuals with family member who has OA have higher risk of developing OA?
True or false?
true
what are prevention methods for OA?
-Maintain ideal body weight
-Participate regularly in moderate exercise program
-Inactivity and excessive exercise -->premature degeneration of cartilage
-Use good posture, proper body mechanics
-Avoid repetitive stress on joints
what are the clinical manifestations for OA?
-joint pain
-pain, stiffness
-Tenderness to touch
-Swelling related to excess fluid in joint
-Crepitus of joint
-Bone spurs
-Decreased range of motion (ROM)
-unsteady gait
-decrease ability to perform ADL = depression
what are the OA required for interprofessional care from:
-primary care provider
- Rheumatologist
-Physical therapist (PT) and occupational therapist(OT)
-Orthopedics
is there any cures for OA?
No
what are the Diagnostic test ?
x-ray, MRI, Ultrasounds, joint fluid analysis
- blood test to rule out other causes
Surgical Management: what is the term "Arthroscopy"
remove of Debridement
what is Joint resurfacing ?
Small amount of bone removed, metal replacement is fitted over end of bone• Often used instead of total joint replacement in younger patients
what is joint irrigation ?
fluid injected in joint• May be combined with arthroscopy
what is osteotomy ?
-Surgical removal of wedge of bone above or below joint
-To realign affected joint
-To shift weight away from damaged part of joint
what is joint fusion (arthrodesis) ?
Permanent fusion of two or more bones at a joint using pins, plates, screws, rods.
-owth at site• Used for badly damaged smaller joints in spine, wrist, ankle, fingers, toes
what is Arthroplasty?
Total joint replacement• Damaged joint is removed with plastic, metal, or ceramic
older adults are best candidates for artificial joints bc....
they usually last for 15-20 years
what are complications of Arthroplasty?
infection, blood clots, long-term breakdown of artificial joint
what are pharmacological managements for OA ?
Acetaminophen ( first line of defense)
NSAIDs
Opioids ( if severe )
Topical creams
Corticosteroid injections
what are Nonpharmacological management methods ?
Use of assistive technology• Weight reduction• Adequate rest• Sleep• Resting of joint• Education about the disease• Exercise• Coping techniques
what are lifespan considerations for Children & adolescents?
Juvenile OA• Secondary to a congenital abnormality, genetic condition, or joint injury• Typically occurs in only one or two joints• May be outgrown as child ages
Children with joint abnormalities who do not develop OA in childhood are at increased risk for OA later in life? True or false
true
lifespan considerations in pregnant women?
increased weight of pregnancy --> increases OA-related pain.
In older adults what should you administer ?
Acetaminophen: first-line medication
Narcotics safer than NSAID
what are the nursing inventions focus on:
-Reducing pain
-Maintaining mobility and function
-Helping patient learn to use assistive devices
-Preoperative, postoperative care
- Encouraging overweight or obese patient to begin weight-loss program