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DSM-5
A. 5 of more of the following symptoms during the same 2-week period and represent a change from previous functioning: at least one of the symptoms is either depressed mood or loss of interest of pleasure
depressed mood most of the day, nearly every day
markedly diminished interest or pleasure in all, or almost all activities most of the day, nearly everyday
significant weight loss when not dieting or weight gain
insomnia or hypersomnia nearly everyday
psychomotor agitation or retardation nearly every day
fatigue or loss of energy nearly every day
feelings of worthlessness or excessive or inappropriate guilt nearly every day
diminished ability to think or concentrate, or indecisiveness, nearly every day
recurrent thoughts of death, recurrent suicidal ideation without or with a plan
B. symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning
C. episode is not attributable to the physiological effects of a substance or to another medical condition
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