01 Non Melanocytic and Malignant lesions of the_skin (copy)

Actinic Keratosis

Skin condition caused by ultraviolet radiation damage, considered precancerous for squamous cell carcinoma, characterized by tan-brown or pink/red colored lesions with rough yellowish brown or white adherent scale.

Squamous Cell Carcinoma

Skin cancer primarily caused by DNA damage induced by UV light exposure, characterized by sharply defined red scaling plaques, nodular invasive lesions, and may appear as squamous cell carcinoma in situ when not invaded through the basement membrane.

Langerhans Cell Histiocytosis (LCH)

A group of conditions caused by the proliferation of dendritic (Langerhan) cells, forming granulomas with eosinophils.

Unifocal LCH

Characterized by a single osteolytic bony lesion with soft tissue swelling.

CD1a+

Marker for Langerhans cells in LCH histology.

Hand-Schuller-Christian LCH

A type of Langerhans Cell Histiocytosis affecting children between 2-6 years of age.

Skin-limited LCH

LCH primarily affecting the skin.

Sebaceous Carcinoma

Aggressive lesion occurring on the upper eyelid, often mistaken for chalazion.

Angiosarcoma

Highly malignant tumor arising from vascular endothelial cells, commonly found on the scalp of elderly men.

Kaposi’s Sarcoma

Neoplasm characterized by dark blue-purple skin lesions, associated with Human Herpes Virus 8 (HHV-8).

Kaposi's Sarcoma

A type of cancer that is most common in patients with AIDS, lymphoma, or immunosuppression, characterized by lesions on various parts of the body.

Epidemic HIV-associated Kaposi's Sarcoma

A form of Kaposi's sarcoma associated with HIV that presents with disseminated lesions, plaque lesions, and violaceous lesions.

Spindle Cells

Cells with a elongated, spindle-like shape, often seen in Kaposi's sarcoma lesions.

Punch Biopsy

A type of skin biopsy where a cylindrical core of tissue is removed using a sharp, hollow instrument, often used for superficial and benign lesions.