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Name | Mastery | Learn | Test | Matching | Spaced |
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Asparagine - toxicity?
Neurotoxicity
Cisplatin - toxicity?
Ototoxic/nephrotoxic, hypomagnasaemia, peripheral neuropathy
Vincristine/vinblastine - toxicity?
‘Christ my nerves, Blast my bones’
Vincristine - peripheral neuropathy
Vinblastine - myelosuppression
Bleomycin - toxicity?
Pulmonary fibrosis
Doxorubicin - toxicity?
Cardiotoxic
Cyclophosphamide - toxicity?
Nephro/bladder toxic, SIADH, myelosuppression
Methotrexate - toxicity?
Nephrotoxic, myelosuppression, mucositis, liver fibrosis, lung fibrosis
Rituximab - risk of which infection?
High risk of latent Hep B reactivation, so need to be screened before starting.
Rituximab targets and suppresses B-cells. When these are suppressed, it can allow Hep B to reactivate, potentially leading to severe liver problems. If screening is positive, pt needs to be started on antivirals