CHEM CH 24 bishop

T/F: PTH and 1,25(OH)2D [Vitamin D] are the principal hormones involved in the normal physiologic regulation of calcium homeostasis.

True

The primary organs involved in the maintenance of calcium homeostasis are the investing, ___, and kidney.

Bone

Skin, ___, and kidney are involved in the production of the active metabolite of vitamin D.

Liver

T/F: Cod liver oil is a source of vitamin D.

True

T/F: 1,25 (OH)2D is the best blood test for determining adequacy of vitamin D stores in the body.

False

T/F: PTHrP is produced by some cancers and often leads to cancer-associated hypercalcemia.

True

T/F: 1,25 (OH)2D due to 1-hydroxylase activity in macrophages, may be produced to excess in granulomatous diseases and lymphoid disorders, leading to hypercalcemia.

False

In PHPT, the defect primarily lies in ___. In secondary hyperparathyroidism, the defect primarily lies with the threat of ___ to the body.

parathyroid, hypocalcemia

Development of __ __ is the primary compilation of hypercalciuria (increased urinary exception of calcium)

kidney stones

__ __ is the most common cause of hypoparathyroidism.

neck surgery

__ is a type of bone most rapidly lost in response to hypogonadism and glucocorticoid therapy.

trabecular bone

__ cells in bone are responsible of bone resorption, and __ cells are responsible for bone formation.

osteoclasts, osteoblasts

__ is the most prevalent metabolic bone disease in the united states.

osteoporosis

T/F: Hormone replacement does not inhibit bone resorption in osteoporotic patients.

False

T/F: Triparatide is the only drug currently approved by the FDA for the treatment of osteoporosis that directly stimulates bone formation (i.e. it is not an antiresorptive drug).

True