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Neuroscience & Behavior
Everything psychological is also biological.
Every mood, behavior, and thought comes from the brain and nervous system.
Neuroscience
The study of the brain and nervous system.
Began in the early 1800s with Franz Gall, who created phrenology.
Phrenology
A false/pseudoscientific theory.
Claimed bumps on the skull could predict mental traits.
Neuron
A nerve cell.
The basic building block of the nervous system.
Dendrites
Branching extensions of a neuron.
Receive information and carry it toward the cell body.
Dendritic Spines
Small structures on dendrites.
Help transmit signals and store synaptic strength.
Receptor Sites
Areas on the cell membrane sensitive to neurotransmitters.
Work like a lock and key.
Each receptor fits only one neurotransmitter.
Neuron’s Three Basic Tasks
Receive information
Carry information
Pass information to the next neuron, muscle, or gland
Cell Body (Soma)
The neuron’s life support center.
Contains the nucleus and keeps the cell alive.
Axon
Long extension that sends electrical impulses away from the cell body.
Sends messages to other neurons, muscles, or glands.
Can be several feet long.
Axon Hillock
Where the cell body becomes the axon.
Decides whether the neuron will fire.
Myelin Sheath
Fatty layer that insulates the axon.
Speeds up neural impulses.
Multiple Sclerosis (MS)
An autoimmune disease that damages the myelin sheath.
Causes slowed communication to muscles.
Symptoms include:
Vision loss
Pain
Fatigue
Poor coordination
Loss of muscle control
Nodes of Ranvier
Gaps in the myelin sheath.
Discovered in 1878 by Louis-Antoine Ranvier.
Allow impulses to jump from node to node, speeding up communication.
Terminal Branches
Small, tree-like ends of the axon.
Send messages to neurons, muscles, or glands.
Terminal Buttons
Bulb-shaped ends of terminal branches.
Store and release neurotransmitters.
Form junctions with other cells.
Neural Communication
Neurons generate electricity from chemical changes.
All-or-None Principle (Law)
A neuron either fires or it doesn’t.
If it fires, it always fires at the same intensity.
All action potentials have equal strength.
Action Potential
A neural impulse.
A brief electrical charge that travels down the axon.
Depolarization
Occurs when positively charged ions enter the axon.
This allows the electrical charge to move down the axon.
Repolarization
After the impulse passes, the neuron becomes polarized again.
Positively charged ions are pumped out.
Resting Potential
The neuron’s resting state.
The neuron is ready to fire an action potential.
Refractory Period
The rest/recharge phase after a neuron fires.
During the absolute refractory period, the neuron cannot fire again, no matter how strong the signal is.
Once this period is over, the neuron can fire again.
Synapse
A tiny, fluid-filled gap between:
The axon terminal of one neuron
The dendrite of the next neuron
Electrical signals cannot jump this gap
Excitatory Effect
Makes the receiving neuron more likely to fire.
Increases the chance of an action potential.
Inhibitory Effect
Makes the receiving neuron less likely to fire.
Decreases the chance of an action potential
Neurotransmitters
chemical messengers that travel across the synapse from one neuron to another.
They influence whether the receiving neuron will generate an action potential.
Agonists
Drugs that mimic or enhance the effects of neurotransmitters
Example: Morphine mimics endorphins
Antagonists
Drugs that block neurotransmitters
Example: Botox blocks acetylcholine (ACh)
Dopamine
Responsible for motor movement, learning, attention, alertness, emotions
Important in addiction
Too much → schizophrenia
Too little → Parkinson’s disease
Serotonin
Affects mood, hunger, sleep, arousal, pain
Too little → depression
Norepinephrine
Controls alertness and arousal
Associated with eating
Too little → depression
Too much → schizophrenia
GABA (Gamma-aminobutyric Acid)
Inhibitory neurotransmitter
Controls muscle activity, eating & sleeping
Too little → seizures, tremors, insomnia
Noradrenaline
Helps control alertness and arousal
Accelerates heart rate
Affects eating, learning, and memory
Too much or too little → mood disorders
Acetylcholine (ACh)
Controls learning, memory, muscle contraction, motor movement
Linked to Alzheimer’s disease
Related to nicotine addiction
Endorphins
Natural opiates
Released during pain and vigorous exercise
Reduce pain and create euphoria
Linked to addictions and OCD
Glutamate
Excitatory neurotransmitter
Involved in memory
Too much → overstimulation → migraines or seizures
Nervous System
The electrochemical communication system of the body
The body’s primary information system
Two main parts:
Peripheral Nervous System (PNS)
Central Nervous System (CNS)
Peripheral Nervous System (PNS)
Sensory and motor nerves connecting the brain and spinal cord to the rest of the body
“Peripheral” = outer region
Subdivided into:
Somatic Nervous System
Autonomic Nervous System
Somatic Nervous System
Controls skeletal muscles
Handles voluntary movement
Contains motor nerves for voluntary muscles
Autonomic Nervous System
Controls glands and internal organs
Has two divisions:
Sympathetic
Parasympathetic
Sympathetic Division
Arouses the body
Prepares body for fight-or-flight
Activated during stress or danger
Parasympathetic Division
Calms the body
Returns body to a relaxed state
Opposes the sympathetic system
Central Nervous System (CNS)
Made up of:
Brain
Spinal cord
Brain: main site of information processing
Spinal cord: main pathway to and from the brain