Chapter 16- How Genes Work

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20 Terms

1

Transcription

________ is the process of using a DNA template to make an RNA molecule that has a base sequence complementary to the DNA.

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2

viral enzyme

A(n) ________ called reverse transcriptase synthesizes a DNA version of the RNA genes.

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3

single addition

A(n) ________ or deletion throws the sequence of codons, or the reading frame, out of register.

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4

central dogma

The ________ summarizes the flow of information from DNA to proteins.

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5

Translation

________ is the process of using the information in the base sequence of mRNA to synthesize proteins.

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6

genetic screen

A(n) ________ is any technique for picking particular types of mutants out of many randomly generated mutants.

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7

Errors

________ in crossing over or in DNA synthesis can lead to the presence of one or more additional copies of a segment which is a duplication.

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8

DNA

If a change in ________ sequence leads to a change in the third position of a codon, it is less likely to alter the amino acid in the protein.

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9

Information

________ in the messenger RNA is translated into proteins by ribosomes.

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10

Point mutations

________ and chromosome mutations are random changes in DNA that can produce new genes, alleles, and traits.

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11

particular amino acid

A group of three bases that specifies a(n) ________ is called a codon.

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12

Alleles

________ that do not function at all are called null alleles, or loss- oιfunction ________.

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13

mutation

A(n) ________ is any permanent change in an organisms DNA.

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14

Stop codons

________ do not code for any amino acid but signal the end of the reading frame and therefore, the end of the polypeptide.

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15

DNA

________ is transcribed to RNA by RNA polymerase.

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16

One-gene, one-enzyme hypothesis

Beadle and Tatum proposed that each of the mutants could not make a particular compound because it lacked an enzyme required to synthesize the compound

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17

Triplet code

A three-base code, known as a triplet code, is the shortest genetic word to code for at least 20 amino acids.

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18

Genetic code

is the rules that specify the relationship between a sequence of nucleo des in DNA or RNA and 1e sequence of amino acids in a protein.

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19

One-gene, one-enzyme hypothesis

Beadle and Tatum proposed that each of the mutants could not make a particular compound because it lacked an enzyme required to synthesize the compound.

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20

Start codons

set the reading frame of the message, locking in which set of three-base triplets constitute “words.

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