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What is a critical value?
A result significantly outside of the reference range, represents a pathophysiologic condition.
What is a WBC count above normal called?
Leukocytosis
What is a WBC count below normal called?
Leukopenia
What is a RBC count above normal called?
Polycythemia
What is a RBC count below normal called?
Anemia
What do neutrophils do?
Removes and destroys bacteria, cellular debris, and solid particles
What do eosinophils do?
destroy protozoa and parasitic worms, release anti-inflammatory substances in antigen-antibody reactions. Increased eosinophil count commonly seen in asthma
What do basophils do?
contains histamine and heparin. Histamine = vasodilation and attracts other WBC to inflamed sit. Heparin inhibits blood clotting
What do monocytes do?
Phagocytize bacteria, dead cells, cell fragments, and viral-infected cells
What do lymphocytes do?
Function in immune response by acting against virus-infected cells and tumors (T lymphocytes), produce antibodies (B lymphocytes)
What do neutrophils consist of?
Neutrophilia, neutropenia, bands, segmented neutrophils
What are electrolytes?
Charged ions influencing the function of enzymes; disturbances may disrupt normal cellular function
What are enzymes?
proteins regulating all chemical reactions occurring within cells (metabolism, protein synthesis)
What enzyme tests are commonly performed?
Liver function test - liver damage assessed by abnormal increased in hepatic enzymes
Pancreatic enzyme tests - pancreatitis will have abnormal levels of lipase and amylase
Muscle enzyme tests - Ischemic damage to the heart, brain & skeletal muscle tissue will have elevated CPK
What is included in a basic chemistry panel?
Glucose, anion gap, lactate, sodium, potassium, chloride, bicarbonate,
What is a gram stain?
Test that can determine if the offending organism is gram positive or gram negative and its shape. Suspected infection in lungs or airways may benefit from analysis of a sputum sample (sputum gram stain)
What are indications for PFTs?
Evaluate pulmonary causes of dyspnea, Differentiate between obstructive and restrictive pulmonary disorders, Assess the severity of the pathophysiologic impairment
How is tidal volume evaluated?
500
breathe normally for one minute then divide by RR
How is inspiratory capacity evaluated?
3600
inhale maximally at the end of a normal exhalation
How is inspiratory reserve volume evaluated?
3100
breathe in normally then exhale maximally
How is expiratory reserve capacity evaluated?
1200
breathe normally for a few breaths and then exhale maximally
How is vital capacity evaluated?
4800
Exhale maximally then inhale as deeply as possible
What does residual volume show?
1200
gauges air trapping
What does functional reserve capacity show?
2400
Quantifies hyperinflation
What does total lung capacity show?
6000
Identifies restrictive patterns
What is forced expiratory volume timed?
maximum volume of gas that can be exhaled over a specific time period
What equipment is needed for a chest tube setup?
Tube/thoracic catheter and drainage device
What is the chest tube drainage system?
Includes collection chamber, water seal (2cm H2O), and suction contorl chamber (20cm H2O)
Indications for chest tubes?
Hemothorax, pleural effusion, tension pneumothorax
When should you perform a bronchoscopy?
Either diagnostic or therapeutic. Therapeutic for suctioning of excessive secretions, removal of foreign bodies, and selective lavage
When should a thoracentesis be performed?
Procedure in which excess fluid accumulation (pleural effusion) between the chest cavity and lungs (pleural space) is aspirated through a needle inserted through the chest wall. Diagnostic thoracentesis may be performed to identify the cause of a pleural effusion.
What are the 3 types of pneumothoraces?
Open, closed, tension
What is an open pneumothorax?
Penetrating wound. Air can move freely in and out of the pleural space through the hole in the chest
What is a closed pneumothorax?
Blunt force trauma, intra-alveolar trauma. Chest wall intact. Air can enter pleural space, can’t escape as easily
What is a tension pneumothorax?
Air leaks into pleural space and has no means of escape, creates rapid buildup of positive pressure. UNABLE TO SUSTAIN LIFE. Must needle aspirate or place chest tube
What are the indications of HFNC?
Severe oxygenation issues, high inspiratory flow demand, assistance needed with CO2 removal
What are the benefits of HFNC?
improves oxygenation by washing CO2 from end expiration, reduces dead space, provides PEEP
What interfaces are available for HFNC use?
Nasal cannula, mask, trach attachment
What are the 2 common HFNC devices?
Optiflow/airvo and vapotherm
What is commonly associated with HFNC failure?
Delayed application of NIV and intubation
Normal RBC count in adults?
4.35 to 5.65 million cells/mcL for men
3.92 to 5.13 million cells/mcL for women
Normal WBC count in adults?
4,500-11,00 cells/mcL
What does increased BNP show?
Heart failure
Pressure inside the thoracic cavity drops to what during spontaneous inspiration?
-8 inspiration, -4 exhalation
T/F: Anemia is usually seen in individuals with chronic lung disease.
False
An individual with normal lungs should be able to expire what amount in the first second (FEV1)?
80%
Total Lung Capacity is made up of which of the following?
VT+ERV+IRV+RV
T/F: After a thoracentesis, it is important to watch the pt for signs of a pneumothorax.
True
Therapeutic bronchoscopy is used to
Remove a foreign body
Diagnostic bronchoscopy is used to
Obtain a tissue sample
After normal exhalation, what capacity remains in the lungs?
Functional residual capacity
T/F: To remove air, a chest tube should be placed at the base of the chest
False
Sweat chloride tests for?
Cystic fibrosis
Acid-fast staining tests for
TB
Troponin-I tests for
Possibility of recent MI
Percentages of WBCs?
Neutrophils 40-75%
Eosinophils 0-6%
Basophils 0-1%
Monocytes 2-10%
Lymphocytes 20-45%