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hyaluronic acid
glycosaminoglycan commonly found in the extra cellular matrix
glycogen
high insulin after a meal signals for glucose to be stored as what in the liver?
glycogenesis
process by which glucose is converted to glycogen and stored in liver
glycogenolysis
process by which glycogen is broken down for energy during vigorous exercise
glycolysis
pathway that breaks down glucose into two pyruvate and generates cellular energy and intermediates for other pathways
MODY2: mature onset diabetes of young
result of mutation of hexokinase
Acetyl CoA
what pyruvate converts into before entering the citric acid cycle
pyruvate dehydrogenase complex
what mediates the conversion of pyruvate into acetyl coA
beriberi
condition caused by vitamin B1 deficiency which prevent the PDH complex from functioning
lactate
high NADH levels favors the conversion of pyruvate into what?
oxaloacetate
during prolonged starvation what is pyruvate converted into in order for gluconeogenesis to occur
tricarboxylic acid cycle/ citric acid cycle
carbohydrate, amino acid, and fatty acid metabolism all converge at which metabolic pathway?
transported to liver to make glucose
what happens to lactate when it acumulates in muscle
gluconeogenesis
conversion of lactate to pyruvate to glucose in the liver
lactic acid cycle/ cori cycle
metabolic pathway that moves lactic acid from muscle to liver and returns glucose to the muscles to be metabolized again, continuing the cycle
rapid ATP production and prevention of lactic acidosis
main functions of the cori cycle
g6PD/NADPH in HMS pentose phosphate pathway
only source of glutathione in RBCs
pentose phosphate pathway
which pathway provides intermediates for nucleotide synthesis
hypoxia
result of CO disrupting oxygen delivery by hemoglobin in the ETC
Red blood cells
which cells are most affected by G6PD deficiency
high insulin, low ATP
under what condition is glycolysis activated