BIO 108: Blood (WBCs)

White blood cells (WBCs) or __ is part of the immune system.

leukocytes

White blood cells do not have __ but have nuclei and other organelles

hemoglobin

Major histocompatibility antigens (MHC) are …

cell identity markers

What are these functions of:

• Defend against pathogens

• Remove toxins and wastes

• Attack abnormal cells

• Involved in both immunity responses - inflammation & inflection

White Blood Cells

Most WBCs in __ tissue proper & __ system organs.

connective, lymphatic

What is the process by which WBCs leave the blood stream?

Emigration

What helps WBC stick to blood vessel wall?

Adhesion Molecules

__ are on blood vessel.

Selectins

__ are on white blood cells.

Integrins

__ is abnormally low WBC count.

Leukopenia

__ is abnormally high WBC count.

Leukocytosis

__ is extremely high WBC count.

Leukemia

__ are usually first to respond. {Marines}

Neutrophil

__ calm things down afterwards. {Politicians}

Eosinophil

__ bring attention to the fight. {Media}

Basophil

__ come in later with a lot of troops, reorganize & clean up. {Army}

Monocytes

__ are true killers. {Navy Seals}

Lymphocyte

What has the ability to recirculate and have a much longer lifespan?

Lymphocytes

Lymphocytes are part of the body’s specific defense system, and has __.

memory of pathogens.

Which class of Lymphocytes:

• Cell-mediated immunity

• Viruses, fungi, rejections, cancer cells

• Attack foreign cells directly

T cells

Which class of Lymphocytes:

• Humoral immunity

• Destroy bacteria

• Become plasma cells → release antibodies

B cells

Which class of Lymphocytes:

• Detect and destroy abnormal tissue cell

Natural killer cells

What are develop into macrophages in peripheral tissues?

Monocytes

What differentiate into progenitor cells which produce all WBCs except lymphocytes?

Myeloid

__ are produced by lymphoid stem cells.

Lymphocytes

Megakaryocyte produce __ that are involved in human clotting system.

platelets

These are functions of __:

• Stimulates formation of tissue factor - forms positive feedback loop (intrinsic and extrinsic)

• Accelerates clotting

• Normally, a small puncture wound stops bleeding in 1-4 minutes

Thrombin