amino acids

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Glycine

Gly, G

Nonpolar and no stereo center

Inside of protein

N/a

N/a

N/a

NTK

• in beta turns

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Alanine

Ala, A

Non polar

Inside protein

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Valine

Val, V

Non polar and bulky

Inside of protein

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Leucine

Leu, L

Non polar and bulky

Inside protein

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Isoleucine

Ile, I

Nonpolar and bulky

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Phenylalanine

Phe, F

Aromatic and UV absorber

N/a

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Tyrosine

Tyr, Y

Aromatic UV absorber

N/a

10

OH

0(ph<pka)→-1 (ph>pka)

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Tryptophan

Trp, W ——- “Twyptophan”

Aromatic UV absorber. Has 2 rings

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Methionine

Met, M

Nonpolar and bulky

Inside protein

N/a

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Cysteine

Cys, C

Polar can form disulfide bonds

Outside of proteins

8

SH

0(ph<pka)→ -1(ph>pka)

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

Serine

Ser, S

Polar and involved in catalysis

Outside of protein

Not titratable

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Threonine

Thr, T

Polar

Not titratable

N/a

NTK

• involved in catalysis

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Arginine

Arg, R “ARRRRRginine”

Charged and involved in catalysis

Outside of protein

12.5

NH

+1(pH<pka)→0(pH>pka)

NTK:

• involved in catalysis

• Called basic since they have their H+ at pH 7

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Lysine

Lys, K -“I liKe Lysine”

Outside of protein

10.5

NH

+1(pH<pka)→0(pH>pka)

NTK:

• involved in catalysis

• Called basic since they have their H+ at pH 7

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Histidine

His, H

Polar

Outside of protein

6

NH

+1(pH<pka)→0(pH>pka)

NTK:

• involved in catalysis

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Proline

Pro, P

Nonpolar

Inside of protein

N/a

NTK

• bulky

• Has a ring as a part of the backbone

• The ring structure constrains its movement

• In beta turns

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Glutamate

Glu, E -“Glue”

Charged

Outside of proteins

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Aspartate

Asp D “Aspardate”

Negatively charged R group

Outside protein

3.9

OH

0(pH<pKa)→-1(pH>pKa)

NTK

• acidic

• Involved in catalysis

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Glutamine

Glu Q “Cutamine = Qutamine”

Polar

Outside protein

N/a

NTK

• Involved in catalysis

Name

nickname

Type

Located where?

pka of side chain

type of side chain (OH,SH,NH?)

charge progression (0→-1,+1→0)

NTK

Asparagine

Asn N “AsperaNine”

Polar Amino acid

Outside protein

N/a

NTK

• involved in catalysis