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Adalimumab brand
Humira
Adalimumab class
TNF inhibitor
Adalimumab MOA
Binds and inhibits tumor necrosis factor alpha, reducing inflammation and altering immune response
Adalimumab side effects
Headache, rash, nausea, injection site reaction, hyperlipidemia, hematuria, elevation of ALK/CK, arthralgia
Adalimumab dose
40 mg SQ q2w
Adalimumab contraindications
Active infections
Adalimumab BBW
Increased risk of serious infections, lymphoma or other malignancies may occur
Etanercept brand
Enbrel
Etanercept class
TNF inhibitor
Etanercept MOA
Binds and inhibits tumor necrosis factor alpha, reducing inflammation and altering immune response
Etanercept dose
50 mg SQ qW-q2W depending on disease state
Etanercept BBW
Increased risk of serious infections, lymphoma or other malignancies may occur, active tuberculosis has been reported
Potassium chloride brand
Klor-Con, Micro-K
Potassium chloride class
Electrolytes
Potassium chloride MOA
Replaces potassium
Potassium chloride side effects
N/V, flatulence, abdominal discomfort, diarrhea
Potassium chloride dose
20-25 mEQ PO qD
Potassium chloride contraindications
Hyperkalemia, delayed GI transit, GI obstruction
Vitamine D brand
Ergocalciferol (D2), cholecalciferol (D3)
Vitamin D class
Vitamin D
Vitamin D MOA
Stimulates intestinal calcium and phosphate absorption, stimulates bone mineralization
Vitamin D side effects
Hypercalcemia, nausea, anemia, weakness
Vitamin D dose
400-2000 u PO qD
Vitamine D contraindications
Hypercalcemia, hypervitaminosis D
Ferrous sulfate brand
Feosol, Fer-in-Sol, Slow FE, Feratab
Ferrous sulfate class
Iron supplement
Ferrous sulfate MOA
Source of elemental iron
Ferrous sulfate side effects
Dyspepsia, N/V, constipation, diarrhea, dark fecal discoloration
Ferrous sulfate dose
150-325 mg qD
Ferrous sulfate contraindications
Hemolytic anemia, ulcerative colitis
Folic acid class
Vitamin B-9
Folic acid MOA
Participates in DNA synthesis and erythropoiesis
Folic acid side effects
Nausea, abdominal pain, flatulence, irritability, rash
Folic acid dose
1 mg PO qD
Cyanocobalamin class
Vitamin B-12
Cyanocobalamin MOA
Essential component and participant in physiologic systems
Cyanocobalamin side effects
Headache, nausea, anxiety, nervousness
Cyanocobalamin dose
1000 mcm SQ/IV qMonth
Lubiprostone brand
Amitiza
Lubiprostone class
Chloride channel activator, GI agent
Lubiprostone dose
Constipation: 24 mcg BID, IBS with constipation: 8 mcg BID, opioid induced constipation: 8 mcg BID
Lubiprostone contraindications
Syncope, hypotension
Lactulose brand
Constulose, Enulose, Generlac, Kristalose
Lactulose class
Ammonium detoxicant laxative
Lactulose dose
10-20 g qD
Lactulose contraindications
Low galactose diet, caution in pts with diabetes since solution contains galactose and lactose, monitor for electrolyte imbalance
Diphenoxylate/atropine brand
Lomotil
Diphenoxylate/atropine class
Antidiarrheal
Diphenoxylate/atropine dose
5 mg diphenoxylate QID PRN
Diphenoxylate/atropine contraindications
Obstructive jaundice, diarrhea associated with pseudomembranous enterocolitis
Rifaximin brand
Xifaxan
Rifaximin class
Rifamycin antibiotic
Rifaximin dose
hepatic encephalopathy: 550 mg PO BID, traveler’s diarrhea: 550 mg TID for 14 days, diarrhea: 200 mg TID for 3 days
Rifaximin contraindications
Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy