AP Bio DNA Enzyme Vocab Quiz

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Last updated 1:59 AM on 2/3/26
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12 Terms

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Topoisomerase

An enzyme that relieves the stress caused by the unzipping of the DNA by helicase by cutting, swiveling, and rejoining the sugar backbone

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Helicase

An enzyme that unzips the parent DNA strand by breaking the hydrogen bonds between the base pairs

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Primase

An enzyme that adds RNA primer

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DNA Polymerase III

Enzyme that catalyzes the elongation of the new DNA strand, builds the complement strand according to whatever the original strand bases are

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Leading strand

Where DNA polymerase follows helicase and builds complement strand as one long segment from 5’ to 3’

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Lagging strand

Built in many segments since it is going in the opposite direction as helicase

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Okazaki fragments

Short segments of new DNA on the lagging strand

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DNA ligase

Enzyme that joins the gaps in the sugar backbone that DNA polymerase I left

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DNA Polymerase I

Removes the primer and replaces it with DNA

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Nuclease

Enzyme that cuts out damaged DNA

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Telomerase

Maintains the telomeres (ends of chromosomes) in gametes

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Single-strand binding protein

Protein that attaches to one strand and keeps the unzipped strands from resealing

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