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Like my friend Kylie read this to me "**Civil Disobedience** By Henry David Thoreau 1849 I heartily accept the motto, "That government is best which governs least"; and I should like to see it acted up to more rapidly and systematically. Carried out, it finally amounts to this, which also I believe- "That government is best which governs not at all"; and when men are prepared for it, that will be the kind of government which they will have. Government is at best but an expedient; but most governments are usually, and all governments are sometimes, inexpedient. The objections which have been brought against a standing army, and they are many and weighty, and deserve to prevail, may also at last be brought against a standing government. The standing army is only an arm of the standing government. The government itself, which is only the mode which the people have chosen to execute their will, is equally liable to be abused and perverted before the people can act through it. Witness the present Mexican war, the work of comparatively a few individuals using the standing government as their tool; for, in the outset, the people would not have consented to this measure. This American government- what is it but a tradition, though a recent one, endeavoring to transmit itself unimpaired to posterity, but each instant losing some of its integrity? It has not the vitality and force of a single living man; for a single man can bend it to his will. It is a sort of wooden gun to the people themselves. But it is not the less necessary for this; for the people must have some complicated machinery or other, and hear its din, to satisfy that idea of government which they have. Governments show thus how successfully men can be imposed on, even impose on themselves, for their own advantage. It is excellent, we must all allow. Yet this government never of itself furthered any enterprise, but by the alacrity with which it got out of its way. It does not keep the country free. It does not settle the West. It does not educate. The character inherent in the American people has done all that has been accomplished; and it would have done somewhat more, if the government had not sometimes got in its way. For government is an expedient by which men would fain succeed in letting one another alone; and, as has been said, when it is most expedient, the governed are most let alone by it. Trade and commerce, if they were not made of india-rubber, would never manage to bounce over the obstacles which legislators are continually putting in their way; and, if one were to judge these men wholly by the effects of their actions and not partly by their intentions, they would deserve to be classed and punished with those mischievous persons who put obstructions on the railroads. But, to speak practically and as a citizen, unlike those who call themselves no- government men, I ask for, not at once no government, but at once a better government. Let every man make known what kind of government would command his respect, and that will be one step toward obtaining it. After all, the practical reason why, when the power is once in the hands of the people, a majority are permitted, and for a long period continue, to rule is not because they are most likely to be in the right, nor because this seems fairest to the minority, but because they are physically the strongest. But a government in which the majority rule in all cases cannot be based on justice, even as far as men understand it. Can there not be a government in which majorities do not virtually decide right and wrong, but conscience?- in which majorities decide only those questions to which the rule of expediency is applicable? Must the citizen ever for a moment, or in the least degree, resign his conscience to the legislation? Why has every man a conscience, then? I think that we should be men first, and subjects afterward. It is not desirable to cultivate a respect for the law, so much as for the right. The only obligation which I have a right to assume is to do at any time what I think right. It is truly enough said that a corporation has no conscience; but a corporation of conscientious men is a corporation with a conscience. Law never made men a whit more just; and, by means of their respect for it, even the well-disposed are daily made the agents of injustice. A common and natural result of an undue respect for law is, that you may see a file of soldiers, colonel, captain, corporal, privates, powder- monkeys, and all, marching in admirable order over hill and dale to the wars, against their wills, ay, against their common sense and consciences, which makes it very steep marching indeed, and produces a palpitation of the heart. They have no doubt that it is a damnable business in which they are concerned; they are all peaceably inclined. Now, what are they? Men at all? or small movable forts and magazines, at the service of some unscrupulous man in power? Visit the Navy-Yard, and behold a marine, such a man as an American government can make, or such as it can make a man with its black arts- a mere shadow and reminiscence of humanity, a man laid out alive and standing, and already, as one may say, buried under arms with funeral accompaniments, though it may be, "Not a drum was heard, not a funeral note, As his corse to the rampart we hurried; Not a soldier discharged his farewell shot O'er the grave where our hero we buried." The mass of men serve the state thus, not as men mainly, but as machines, with their bodies. They are the standing army, and the militia, jailers, constables, posse comitatus, etc. In most cases there is no free exercise whatever of the judgment or of the moral sense; but they put themselves on a level with wood and earth and stones; and wooden men can perhaps be manufactured that will serve the purpose as well. Such command no more respect than men of straw or a lump of dirt. They have the same sort of worth only as horses and dogs. Yet such as these even are commonly esteemed good citizens. Others- as most legislators, politicians, lawyers, ministers, and office-holders- serve the state chiefly with their heads; and, as they rarely make any moral distinctions, they are as likely to serve the devil, without intending it, as God. A very few- as heroes, patriots, martyrs, reformers in the great sense, and men- serve the state with their consciences also, and so necessarily resist it for the most part; and they are commonly treated as enemies by it. A wise man will only be useful as a man, and will not submit to be "clay," and "stop a hole to keep the wind away," but leave that office to his dust at least: "I am too high-born to be propertied, To be a secondary at control, Or useful serving-man and instrument To any sovereign state throughout the world." He who gives himself entirely to his fellow-men appears to them useless and selfish; but he who gives himself partially to them is pronounced a benefactor and philanthropist. How does it become a man to behave toward this American government today? I answer, that he cannot without disgrace be associated with it. I cannot for an instant recognize that political organization as my government which is the slave's government also. All men recognize the right of revolution; that is, the right to refuse allegiance to, and to resist, the government, when its tyranny or its inefficiency are great and unendurable. But almost all say that such is not the case now. But such was the case, they think, in the Revolution Of '75. If one were to tell me that this was a bad government because it taxed certain foreign commodities brought to its ports, it is most probable that I should not make an ado about it, for I can do without them. All machines have their friction; and possibly this does enough good to counterbalance the evil. At any rate, it is a great evil to make a stir about it. But when the friction comes to have its machine, and oppression and robbery are organized, I say, let us not have such a machine any longer. In other words, when a sixth of the population of a nation which has undertaken to be the refuge of liberty are slaves, and a whole country is unjustly overrun and conquered by a foreign army, and subjected to military law, I think that it is not too soon for honest men to rebel and revolutionize. What makes this duty the more urgent is the fact that the country so overrun is not our own, but ours is the invading army. Paley, a common authority with many on moral questions, in his chapter on the "Duty of Submission to Civil Government," resolves all civil obligation into expediency; and he proceeds to say that "so long as the interest of the whole society requires it, that is, so long as the established government cannot be resisted or changed without public inconveniency, it is the will of God... that the established government be obeyed- and no longer. This principle being admitted, the justice of every particular case of resistance is reduced to a computation of the quantity of the danger and grievance on the one side, and of the probability and expense of redressing it on the other." Of this, he says, every man shall judge for himself. But Paley appears never to have contemplated those cases to which the rule of expediency does not apply, in which a people, as well as an individual, must do justice, cost what it may. If I have unjustly wrested a plank from a drowning man, I must restore it to him though I drown myself. This, according to Paley, would be inconvenient. But he that would save his life, in such a case, shall lose it. This people must cease to hold slaves, and to make war on Mexico, though it cost them their existence as a people. In their practice, nations agree with Paley; but does any one think that Massachusetts does exactly what is right at the present crisis? "A drab of state, a cloth-o'-silver slut, To have her train borne up, and her soul trail in the dirt." Practically speaking, the opponents to a reform in Massachusetts are not a hundred thousand politicians at the South, but a hundred thousand merchants and farmers here, who are more interested in commerce and agriculture than they are in humanity, and are not prepared to do justice to the slave and to Mexico, cost what it may. I quarrel not with far-off foes, but with those who, near at home, cooperate with, and do the bidding of those far away, and without whom the latter would be harmless. We are accustomed to say, that the mass of men are unprepared; but improvement is slow, because the few are not materially wiser or better than the many. It is not so important that many should be as good as you, as that there be some absolute goodness somewhere; for that will leaven the whole lump. There are thousands who are in opinion opposed to slavery and to the war, who yet in effect do nothing to put an end to them; who, esteeming themselves children of Washington and Franklin, sit down with their hands in their pockets, and say that they know not what to do, and do nothing; who even postpone the question of freedom to the question of free trade, and quietly read the prices-current along with the latest advices from Mexico, after dinner, and, it may be, fall asleep over them both. What is the price-current of an honest man and patriot today? They hesitate, and they regret, and sometimes they petition; but they do nothing in earnest and with effect. They will wait, well disposed, for others to remedy the evil, that they may no longer have it to regret. At most, they give only a cheap vote, and a feeble countenance and God-speed, to the right, as it goes by them. There are nine hundred and ninety-nine patrons of virtue to one virtuous man. But it is easier to deal with the real possessor of a thing than with the temporary guardian of it. All voting is a sort of gaming, like checkers or backgammon, with a slight moral tinge to it, a playing with right and wrong, with moral questions; and betting naturally accompanies it. The character of the voters is not staked. I cast my vote, perchance, as I think right; but I am not vitally concerned that that right should prevail. I am willing to leave it to the majority. Its obligation, therefore, never exceeds that of expediency. Even voting for the right is doing nothing for it. It is only expressing to men feebly your desire that it should prevail. A wise man will not leave the right to the mercy of chance, nor wish it to prevail through the power of the majority. There is but little virtue in the action of masses of men. When the majority shall at length vote for the abolition of slavery, it will be because they are indifferent to slavery, or because there is but little slavery left to be abolished by their vote. They will then be the only slaves. Only his vote can hasten the abolition of slavery who asserts his own freedom by his vote. I hear of a convention to be held at Baltimore, or elsewhere, for the selection of a candidate for the Presidency, made up chiefly of editors, and men who are politicians by profession; but I think, what is it to any independent, intelligent, and respectable man what decision they may come to? Shall we not have the advantage of his wisdom and honesty, nevertheless? Can we not count upon some independent votes? Are there not many individuals in the country who do not attend conventions? But no: I find that the respectable man, so called, has immediately drifted from his position, and despairs of his country, when his country has more reason to despair of him. He forthwith adopts one of the candidates thus selected as the only available one, thus proving that he is himself available for any purposes of the demagogue. His vote is of no more worth than that of any unprincipled foreigner or hireling native, who may have been bought. O for a man who is a man, and, as my neighbor says, has a bone in his back which you cannot pass your hand through! Our statistics are at fault: the population has been returned too large. How many men are there to a square thousand miles in this country? Hardly one. Does not America offer any inducement for men to settle here? The American has dwindled into an Odd Fellow-one who may be known by the development of his organ of gregariousness, and a manifest lack of intellect and cheerful self-reliance; whose first and chief concern, on coming into the world, is to see that the almshouses are in good repair; and, before yet he has lawfully donned the virile garb, to collect a fund for the support of the widows and orphans that may be; who, in short, ventures to live only by the aid of the Mutual Insurance company, which has promised to bury him decently. It is not a man's duty, as a matter of course, to devote himself to the eradication of any, even the most enormous, wrong; he may still properly have other concerns to engage him; but it is his duty, at least, to wash his hands of it, and, if he gives it no thought longer, not to give it practically his support. If I devote myself to other pursuits and contemplations, I must first see, at least, that I do not pursue them sitting upon another man's shoulders. I must get off him first, that he may pursue his contemplations too. See what gross inconsistency is tolerated. I have heard some of my townsmen say, "I should like to have them order me out to help put down an insurrection of the slaves, or to march to Mexico;- see if I would go"; and yet these very men have each, directly by their allegiance, and so indirectly, at least, by their money, furnished a substitute. The soldier is applauded who refuses to serve in an unjust war by those who do not refuse to sustain the unjust government which makes the war; is applauded by those whose own act and authority he disregards and sets at naught; as if the state were penitent to that degree that it differed one to scourge it while it sinned, but not to that degree that it left off sinning for a moment. Thus, under the name of Order and Civil Government, we are all made at last to pay homage to and support our own meanness. After the first blush of sin comes its indifference; and from immoral it becomes, as it were, unmoral, and not quite unnecessary to that life which we have made. The broadest and most prevalent error requires the most disinterested virtue to sustain it. The slight reproach to which the virtue of patriotism is commonly liable, the noble are most likely to incur. Those who, while they disapprove of the character and measures of a government, yield to it their allegiance and support are undoubtedly its most conscientious supporters, and so frequently the most serious obstacles to reform. Some are petitioning the State to dissolve the Union, to disregard the requisitions of the President. Why do they not dissolve it themselves- the union between themselves and the State- and refuse to pay their quota into its treasury? Do not they stand in the same relation to the State that the State does to the Union? And have not the same reasons prevented the State from resisting the Union which have prevented them from resisting the State? How can a man be satisfied to entertain an opinion merely, and enjoy it? Is there any enjoyment in it, if his opinion is that he is aggrieved? If you are cheated out of a single dollar by your neighbor, you do not rest satisfied with knowing that you are cheated, or with saying that you are cheated, or even with petitioning him to pay you your due; but you take effectual steps at once to obtain the full amount, and see that you are never cheated again. Action from principle, the perception and the performance of right, changes things and relations; it is essentially revolutionary, and does not consist wholly with anything which was. It not only divides States and churches, it divides families; ay, it divides the individual, separating the diabolical in him from the divine. Unjust laws exist: shall we be content to obey them, or shall we endeavor to amend them, and obey them until we have succeeded, or shall we transgress them at once? Men generally, under such a government as this, think that they ought to wait until they have persuaded the majority to alter them. They think that, if they should resist, the remedy would be worse than the evil. But it is the fault of the government itself that the remedy is worse than the evil. It makes it worse. Why is it not more apt to anticipate and provide for reform? Why does it not cherish its wise minority? Why does it cry and resist before it is hurt? Why does it not encourage its citizens to be on the alert to point out its faults, and do better than it would have them? Why does it always crucify Christ, and excommunicate Copernicus and Luther, and pronounce Washington and Franklin rebels? One would think, that a deliberate and practical denial of its authority was the only offence never contemplated by government; else, why has it not assigned its definite, its suitable and proportionate, penalty? If a man who has no property refuses but once to earn nine shillings for the State, he is put in prison for a period unlimited by any law that I know, and determined only by the discretion of those who placed him there; but if he should steal ninety times nine shillings from the State, he is soon permitted to go at large again. If the injustice is part of the necessary friction of the machine of government, let it go, let it go: perchance it will wear smooth- certainly the machine will wear out. If the injustice has a spring, or a pulley, or a rope, or a crank, exclusively for itself, then perhaps you may consider whether the remedy will not be worse than the evil; but if it is of such a nature that it requires you to be the agent of injustice to another, then, I say, break the law. Let your life be a counter-friction to stop the machine. What I have to do is to see, at any rate, that I do not lend myself to the wrong which I condemn. As for adopting the ways which the State has provided for remedying the evil, I know not of such ways. They take too much time, and a man's life will be gone. I have other affairs to attend to. I came into this world, not chiefly to make this a good place to live in, but to live in it, be it good or bad. A man has not everything to do, but something; and because he cannot do everything, it is not necessary that he should do something wrong. It is not my business to be petitioning the Governor or the Legislature any more than it is theirs to petition me; and if they should not bear my petition, what should I do then? But in this case the State has provided no way: its very Constitution is the evil. This may seem to be harsh and stubborn and unconciliatory; but it is to treat with the utmost kindness and consideration the only spirit that can appreciate or deserves it. So is an change for the better, like birth and death, which convulse the body. I do not hesitate to say, that those who call themselves Abolitionists should at once effectually withdraw their support, both in person and property, from the government of Massachusetts, and not wait till they constitute a majority of one, before they suffer the right to prevail through them. I think that it is enough if they have God on their side, without waiting for that other one. Moreover, any man more right than his neighbors constitutes a majority of one already. I meet this American government, or its representative, the State government, directly, and face to face, once a year- no more- in the person of its tax- gatherer; this is the only mode in which a man situated as I am necessarily meets it; and it then says distinctly, Recognize me; and the simplest, the most effectual, and, in the present posture of affairs, the indispensablest mode of treating with it on this head, of expressing your little satisfaction with and love for it, is to deny it then. My civil neighbor, the tax-gatherer, is the very man I have to deal with- for it is, after all, with men and not with parchment that I quarrel- and he has voluntarily chosen to be an agent of the government. How shall he ever know well what he is and does as an officer of the government, or as a man, until he is obliged to consider whether he shall treat me, his neighbor, for whom he has respect, as a neighbor and well-disposed man, or as a maniac and disturber of the peace, and see if he can get over this obstruction to his neighborliness without a ruder and more impetuous thought or speech corresponding with his action. I know this well, that if one thousand, if one hundred, if ten men whom I could name- if ten honest men only- ay, if one HONEST man, in this State of Massachusetts, ceasing to hold slaves, were actually to withdraw from this copartnership, and be locked up in the county jail therefor, it would be the abolition of slavery in America. For it matters not how small the beginning may seem to be: what is once well done is done forever. But we love better to talk about it: that we say is our mission, Reform keeps many scores of newspapers in its service, but not one man. If my esteemed neighbor, the State's ambassador, who will devote his days to the settlement of the question of human rights in the Council Chamber, instead of being threatened with the prisons of Carolina, were to sit down the prisoner of Massachusetts, that State which is so anxious to foist the sin of slavery upon her sister- though at present she can discover only an act of inhospitality to be the ground of a quarrel with her- the Legislature would not wholly waive the subject the following winter. Under a government which imprisons any unjustly, the true place for a just man is also a prison. The proper place today, the only place which Massachusetts has provided for her freer and less desponding spirits, is in her prisons, to be put out and locked out of the State by her own act, as they have already put themselves out by their principles. It is there that the fugitive slave, and the Mexican prisoner on parole, and the Indian come to plead the wrongs of his race should find them; on that separate, but more free and honorable, ground, where the State places those who are not with her, but against her- the only house in a slave State in which a free man can abide with honor. If any think that their influence would be lost there, and their voices no longer afflict the ear of the State, that they would not be as an enemy within its walls, they do not know by how much truth is stronger than error, nor how much more eloquently and effectively he can combat injustice who has experienced a little in his own person. Cast your whole vote, not a strip of paper merely, but your whole influence. A minority is powerless while it conforms to the majority; it is not even a minority then; but it is irresistible when it clogs by its whole weight. If the alternative is to keep all just men in prison, or give up war and slavery, the State will not hesitate which to choose. If a thousand men were not to pay their tax-bills this year, that would not be a violent and bloody measure, as it would be to pay them, and enable the State to commit violence and shed innocent blood. This is, in fact, the definition of a peaceable revolution, if any such is possible. If the tax-gatherer, or any other public officer, asks me, as one has done, "But what shall I do?" my answer is, "If you really wish to do anything, resign your office." When the subject has refused allegiance, and the officer has resigned his office, then the revolution is accomplished. But even suppose blood should flow. Is there not a sort of blood shed when the conscience is wounded? Through this wound a man's real manhood and immortality flow out, and he bleeds to an everlasting death. I see this blood flowing now. I have contemplated the imprisonment of the offender, rather than the seizure of his goods- though both will serve the same purpose- because they who assert the purest right, and consequently are most dangerous to a corrupt State, commonly have not spent much time in accumulating property. To such the State renders comparatively small service, and a slight tax is wont to appear exorbitant, particularly if they are obliged to earn it by special labor with their hands. If there were one who lived wholly without the use of money, the State itself would hesitate to demand it of him. But the rich man- not to make any invidious comparison- is always sold to the institution which makes him rich. Absolutely speaking, the more money, the less virtue; for money comes between a man and his objects, and obtains them for him; and it was certainly no great virtue to obtain it. It puts to rest many questions which he would otherwise be taxed to answer; while the only new question which it puts is the hard but superfluous one, how to spend it. Thus his moral ground is taken from under his feet. The opportunities of living are diminished in proportion as what are called the "means" are increased. The best thing a man can do for his culture when he is rich is to endeavor to carry out those schemes which he entertained when he was poor. Christ answered the Herodians according to their condition. "Show me the tribute-money," said he;- and one took a penny out of his pocket;- if you use money which has the image of Caesar on it, and which he has made current and valuable, that is, if you are men of the State, and gladly enjoy the advantages of Caesar's government, then pay him back some of his own when he demands it. "Render therefore to Caesar that which is Caesar's, and to God those things which are God's"- leaving them no wiser than before as to which was which; for they did not wish to know. When I converse with the freest of my neighbors, I perceive that, whatever they may say about the magnitude and seriousness of the question, and their regard for the public tranquillity, the long and the short of the matter is, that they cannot spare the protection of the existing government, and they dread the consequences to their property and families of disobedience to it. For my own part, I should not like to think that I ever rely on the protection of the State. But, if I deny the authority of the State when it presents its tax-bill, it will soon take and waste all my property, and so harass me and my children without end. This is hard. This makes it impossible for a man to live honestly, and at the same time comfortably, in outward respects. It will not be worth the while to accumulate property; that would be sure to go again. You must hire or squat somewhere, and raise but a small crop, and eat that soon. You must live within yourself, and depend upon yourself always tucked up and ready for a start, and not have many affairs. A man may grow rich in Turkey even, if he will be in all respects a good subject of the Turkish government. Confucius said: "If a state is governed by the principles of reason, poverty and misery are subjects of shame; if a state is not governed by the principles of reason, riches and honors are the subjects of shame." No: until I want the protection of Massachusetts to be extended to me in some distant Southern port, where my liberty is endangered, or until I am bent solely on building up an estate at home by peaceful enterprise, I can afford to refuse allegiance to Massachusetts, and her right to my property and life. It costs me less in every sense to incur the penalty of disobedience to the State than it would to obey. I should feel as if I were worth less in that case. Some years ago, the State met me in behalf of the Church, and commanded me to pay a certain sum toward the support of a clergyman whose preaching my father attended, but never I myself. "Pay," it said, "or be locked up in the jail." I declined to pay. But, unfortunately, another man saw fit to pay it. I did not see why the schoolmaster should be taxed to support the priest, and not the priest the schoolmaster; for I was not the State's schoolmaster, but I supported myself by voluntary subscription. I did not see why the lyceum should not present its tax-bill, and have the State to back its demand, as well as the Church. However, at the request of the selectmen, I condescended to make some such statement as this in writing:- "Know all men by these presents, that I, Henry Thoreau, do not wish to be regarded as a member of any incorporated society which I have not joined." This I gave to the town clerk; and he has it. The State, having thus learned that I did not wish to be regarded as a member of that church, has never made a like demand on me since; though it said that it must adhere to its original presumption that time. If I had known how to name them, I should then have signed off in detail from all the societies which I never signed on to; but I did not know where to find a complete list. I have paid no poll-tax for six years. I was put into a jail once on this account, for one night; and, as I stood considering the walls of solid stone, two or three feet thick, the door of wood and iron, a foot thick, and the iron grating which strained the light, I could not help being struck with the foolishness of that institution which treated me as if I were mere flesh and blood and bones, to be locked up. I wondered that it should have concluded at length that this was the best use it could put me to, and had never thought to avail itself of my services in some way. I saw that, if there was a wall of stone between me and my townsmen, there was a still more difficult one to climb or break through before they could get to be as free as I was. I did not for a moment feel confined, and the walls seemed a great waste of stone and mortar. I felt as if I alone of all my townsmen had paid my tax. They plainly did not know how to treat me, but behaved like persons who are underbred. In every threat and in every compliment there was a blunder; for they thought that my chief desire was to stand the other side of that stone wall. I could not but smile to see how industriously they locked the door on my meditations, which followed them out again without let or hindrance, and they were really all that was dangerous. As they could not reach me, they had resolved to punish my body; just as boys, if they cannot come at some person against whom they have a spite, will abuse his dog. I saw that the State was half-witted, that it was timid as a lone woman with her silver spoons, and that it did not know its friends from its foes, and I lost all my remaining respect for it, and pitied it. Thus the State never intentionally confronts a man's sense, intellectual or moral, but only his body, his senses. It is not armed with superior wit or honesty, but with superior physical strength. I was not born to be forced. I will breathe after my own fashion. Let us see who is the strongest. What force has a multitude? They only can force me who obey a higher law than I. They force me to become like themselves. I do not hear of men being forced to have this way or that by masses of men. What sort of life were that to live? When I meet a government which says to me, "Your money or your life," why should I be in haste to give it my money? It may be in a great strait, and not know what to do: I cannot help that. It must help itself; do as I do. It is not worth the while to snivel about it. I am not responsible for the successful working of the machinery of society. I am not the son of the engineer. I perceive that, when an acorn and a chestnut fall side by side, the one does not remain inert to make way for the other, but both obey their own laws, and spring and grow and flourish as best they can, till one, perchance, overshadows and destroys the other. If a plant cannot live according to its nature, it dies; and so a man. The night in prison was novel and interesting enough. The prisoners in their shirt-sleeves were enjoying a chat and the evening air in the doorway, when I entered. But the jailer said, "Come, boys, it is time to lock up"; and so they dispersed, and I heard the sound of their steps returning into the hollow apartments. My room-mate was introduced to me by the jailer as "a first-rate fellow and a clever man." When the door was locked, he showed me where to hang my hat, and how he managed matters there. The rooms were whitewashed once a month; and this one, at least, was the whitest, most simply furnished, and probably the neatest apartment in the town. He naturally wanted to know where I came from, and what brought me there; and, when I had told him, I asked him in my turn how he came there, presuming him to be an honest man, of course; and, as the world goes, I believe he was. "Why," said he, "they accuse me of burning a barn; but I never did it." As near as I could discover, he had probably gone to bed in a barn when drunk, and smoked his pipe there; and so a barn was burnt. He had the reputation of being a clever man, had been there some three months waiting for his trial to come on, and would have to wait as much longer; but he was quite domesticated and contented, since he got his board for nothing, and thought that he was well treated. He occupied one window, and I the other; and I saw that if one stayed there long, his principal business would be to look out the window. I had soon read all the tracts that were left there, and examined where former prisoners had broken out, and where a grate had been sawed off, and heard the history of the various occupants of that room; for I found that even here there was a history and a gossip which never circulated beyond the walls of the jail. Probably this is the only house in the town where verses are composed, which are afterward printed in a circular form, but not published. I was shown quite a long list of verses which were composed by some young men who had been detected in an attempt to escape, who avenged themselves by singing them. I pumped my fellow-prisoner as dry as I could, for fear I should never see him again; but at length he showed me which was my bed, and left me to blow out the lamp. It was like travelling into a far country, such as I had never expected to behold, to lie there for one night. It seemed to me that I never had heard the town clock strike before, nor the evening sounds of the village; for we slept with the windows open, which were inside the grating. It was to see my native village in the light of the Middle Ages, and our Concord was turned into a Rhine stream, and visions of knights and castles passed before me. They were the voices of old burghers that I heard in the streets. I was an involuntary spectator and auditor of whatever was done and said in the kitchen of the adjacent village inn- a wholly new and rare experience to me. It was a closer view of my native town. I was fairly inside of it. I never had seen its institutions before. This is one of its peculiar institutions; for it is a shire town. I began to comprehend what its inhabitants were about. In the morning, our breakfasts were put through the hole in the door, in small oblong-square tin pans, made to fit, and holding a pint of chocolate, with brown bread, and an iron spoon. When they called for the vessels again, I was green enough to return what bread I had left; but my comrade seized it, and said that I should lay that up for lunch or dinner. Soon after he was let out to work at haying in a neighboring field, whither he went every day, and would not be back till noon; so he bade me good-day, saying that he doubted if he should see me again. When I came out of prison- for some one interfered, and paid that tax- I did not perceive that great changes had taken place on the common, such as he observed who went in a youth and emerged a tottering and gray-headed man; and yet a change had to my eyes come over the scene- the town, and State, and country- greater than any that mere time could effect. I saw yet more distinctly the State in which I lived. I saw to what extent the people among whom I lived could be trusted as good neighbors and friends; that their friendship was for summer weather only; that they did not greatly propose to do right; that they were a distinct race from me by their prejudices and superstitions, as the Chinamen and Malays are; that in their sacrifices to humanity they ran no risks, not even to their property; that after all they were not so noble but they treated the thief as he had treated them, and hoped, by a certain outward observance and a few prayers, and by walking in a particular straight though useless path from time to time, to save their souls. This may be to judge my neighbors harshly; for I believe that many of them are not aware that they have such an institution as the jail in their village. It was formerly the custom in our village, when a poor debtor came out of jail, for his acquaintances to salute him, looking through their fingers, which were crossed to represent the grating of a jail window, "How do ye do?" My neighbors did not thus salute me, but first looked at me, and then at one another, as if I had returned from a long journey. I was put into jail as I was going to the shoemaker's to get a shoe which was mended. When I was let out the next morning, I proceeded to finish my errand, and, having put on my mended shoe, joined a huckleberry party, who were impatient to put themselves under my conduct; and in half an hour- for the horse was soon tackled- was in the midst of a huckleberry field, on one of our highest hills, two miles off, and then the State was nowhere to be seen. This is the whole history of "My Prisons." I have never declined paying the highway tax, because I am as desirous of being a good neighbor as I am of being a bad subject; and as for supporting schools, I am doing my part to educate my fellow-countrymen now. It is for no particular item in the tax-bill that I refuse to pay it. I simply wish to refuse allegiance to the State, to withdraw and stand aloof from it effectually. I do not care to trace the course of my dollar, if I could, till it buys a man or a musket to shoot one with- the dollar is innocent- but I am concerned to trace the effects of my allegiance. In fact, I quietly declare war with the State, after my fashion, though I will still make what use and get what advantage of her I can, as is usual in such cases. If others pay the tax which is demanded of me, from a sympathy with the State, they do but what they have already done in their own case, or rather they abet injustice to a greater extent than the State requires. If they pay the tax from a mistaken interest in the individual taxed, to save his property, or prevent his going to jail, it is because they have not considered wisely how far they let their private feelings interfere with the public good. This, then, is my position at present. But one cannot be too much on his guard in such a case, lest his action be biased by obstinacy or an undue regard for the opinions of men. Let him see that he does only what belongs to himself and to the hour. I think sometimes, Why, this people mean well, they are only ignorant; they would do better if they knew how: why give your neighbors this pain to treat you as they are not inclined to? But I think again, This is no reason why I should do as they do, or permit others to suffer much greater pain of a different kind. Again, I sometimes say to myself, When many millions of men, without heat, without ill will, without personal feeling of any kind, demand of you a few shillings only, without the possibility, such is their constitution, of retracting or altering their present demand, and without the possibility, on your side, of appeal to any other millions, why expose yourself to this overwhelming brute force? You do not resist cold and hunger, the winds and the waves, thus obstinately; you quietly submit to a thousand similar necessities. You do not put your head into the fire. But just in proportion as I regard this as not wholly a brute force, but partly a human force, and consider that I have relations to those millions as to so many millions of men, and not of mere brute or inanimate things, I see that appeal is possible, first and instantaneously, from them to the Maker of them, and, secondly, from them to themselves. But if I put my head deliberately into the fire, there is no appeal to fire or to the Maker of fire, and I have only myself to blame. If I could convince myself that I have any right to be satisfied with men as they are, and to treat them accordingly, and not according, in some respects, to my requisitions and expectations of what they and I ought to be, then, like a good Mussulman and fatalist, I should endeavor to be satisfied with things as they are, and say it is the will of God. And, above all, there is this difference between resisting this and a purely brute or natural force, that I can resist this with some effect; but I cannot expect, like Orpheus, to change the nature of the rocks and trees and beasts. I do not wish to quarrel with any man or nation. I do not wish to split hairs, to make fine distinctions, or set myself up as better than my neighbors. I seek rather, I may say, even an excuse for conforming to the laws of the land. I am but too ready to conform to them. Indeed, I have reason to suspect myself on this head; and each year, as the tax-gatherer comes round, I find myself disposed to review the acts and position of the general and State governments, and the spirit of the people, to discover a pretext for conformity. "We must affect our country as our parents, And if at any time we alienate Our love or industry from doing it honor, We must respect effects and teach the soul Matter of conscience and religion, And not desire of rule or benefit." I believe that the State will soon be able to take all my work of this sort out of my hands, and then I shall be no better a patriot than my fellow-countrymen. Seen from a lower point of view, the Constitution, with all its faults, is very good; the law and the courts are very respectable; even this State and this American government are, in many respects, very admirable, and rare things, to be thankful for, such as a great many have described them; but seen from a point of view a little higher, they are what I have described them; seen from a higher still, and the highest, who shall say what they are, or that they are worth looking at or thinking of at all? However, the government does not concern me much, and I shall bestow the fewest possible thoughts on it. It is not many moments that I live under a government, even in this world. If a man is thought-free, fancy-free, imagination-free, that which is not never for a long time appearing to be to him, unwise rulers or reformers cannot fatally interrupt him. I know that most men think differently from myself; but those whose lives are by profession devoted to the study of these or kindred subjects content me as little as any. Statesmen and legislators, standing so completely within the institution, never distinctly and nakedly behold it. They speak of moving society, but have no resting-place without it. They may be men of a certain experience and discrimination, and have no doubt invented ingenious and even useful systems, for which we sincerely thank them; but all their wit and usefulness lie within certain not very wide limits. They are wont to forget that the world is not governed by policy and expediency. Webster never goes behind government, and so cannot speak with authority about it. His words are wisdom to those legislators who contemplate no essential reform in the existing government; but for thinkers, and those who legislate for all time, he never once glances at the subject. I know of those whose serene and wise speculations on this theme would soon reveal the limits of his mind's range and hospitality. Yet, compared with the cheap professions of most reformers, and the still cheaper wisdom and eloquence of politicians in general, his are almost the only sensible and valuable words, and we thank Heaven for him. Comparatively, he is always strong, original, and, above all, practical. Still, his quality is not wisdom, but prudence. The lawyer's truth is not Truth, but consistency or a consistent expediency. Truth is always in harmony with herself, and is not concerned chiefly to reveal the justice that may consist with wrong-doing. He well deserves to be called, as he has been called, the Defender of the Constitution. There are really no blows to be given by him but defensive ones. He is not a leader, but a follower. His leaders are the men of '87- "I have never made an effort," he says, "and never propose to make an effort; I have never countenanced an effort, and never mean to countenance an effort, to disturb the arrangement as originally made, by which the various States came into the Union." Still thinking of the sanction which the Constitution gives to slavery, he says, "Because it was a part of the original compact- let it stand." Notwithstanding his special acuteness and ability, he is unable to take a fact out of its merely political relations, and behold it as it lies absolutely to be disposed of by the intellect- what, for instance, it behooves a man to do here in America today with regard to slavery- but ventures, or is driven, to make some such desperate answer as the following, while professing to speak absolutely, and as a private man- from which what new and singular code of social duties might be inferred? "The manner," says he, "in which the governments of those States where slavery exists are to regulate it is for their own consideration, under their responsibility to their constituents, to the general laws of propriety, humanity, and justice, and to God. Associations formed elsewhere, springing from a feeling of humanity, or any other cause, have nothing whatever to do with it. They have never received any encouragement from me, and they never will." They who know of no purer sources of truth, who have traced up its stream no higher, stand, and wisely stand, by the Bible and the Constitution, and drink at it there with reverence and humility; but they who behold where it comes trickling into this lake or that pool, gird up their loins once more, and continue their pilgrimage toward its fountain-head. No man with a genius for legislation has appeared in America. They are rare in the history of the world. There are orators, politicians, and eloquent men, by the thousand; but the speaker has not yet opened his mouth to speak who is capable of settling the much-vexed questions of the day. We love eloquence for its own sake, and not for any truth which it may utter, or any heroism it may inspire. Our legislators have not yet learned the comparative value of free trade and of freedom, of union, and of rectitude, to a nation. They have no genius or talent for comparatively humble questions of taxation and finance, commerce and manufactures and agriculture. If we were left solely to the wordy wit of legislators in Congress for our guidance, uncorrected by the seasonable experience and the effectual complaints of the people, America would not long retain her rank among the nations. For eighteen hundred years, though perchance I have no right to say it, the New Testament has been written; yet where is the legislator who has wisdom and practical talent enough to avail himself of the light which it sheds on the science of legislation? The authority of government, even such as I am willing to submit to- for I will cheerfully obey those who know and can do better than I, and in many things even those who neither know nor can do so well- is still an impure one: to be strictly just, it must have the sanction and consent of the governed. It can have no pure right over my person and property but what I concede to it. The progress from an absolute to a limited monarchy, from a limited monarchy to a democracy, is a progress toward a true respect for the individual. Even the Chinese philosopher was wise enough to regard the individual as the basis of the empire. Is a democracy, such as we know it, the last improvement possible in government? Is it not possible to take a step further towards recognizing and organizing the rights of man? There will never be a really free and enlightened State until the State comes to recognize the individual as a higher and independent power, from which all its own power and authority are derived, and treats him accordingly. I please myself with imagining a State at least which can afford to be just to all men, and to treat the individual with respect as a neighbor; which even would not think it inconsistent with its own repose if a few were to live aloof from it, not meddling with it, nor embraced by it, who fulfilled all the duties of neighbors and fellow-men. A State which bore this kind of fruit, and suffered it to drop off as fast as it ripened, would prepare the way for a still more perfect and glorious State, which also I have imagined, but not yet anywhere seen. THE END"
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🦠 MICROBIOLOGY — WEEK 1 STUDY NOTES Microbiology Foundations Assigned reading: 1.1 What Our Ancestors Knew 1.2 A Systematic Approach 1.3 Types of Microorganisms 3.1 Spontaneous Generation 3.2 Foundations of Modern Cell Theor/y 1.1 What Our Ancestors Knew First: What is microbiology? Microbiology = the study of very small organisms and infectious agents. Microorganism / microbe = an organism that is generally too small to see without a microscope. Examples include: * Bacteria * Archaea * Fungi such as yeast and molds * Protozoa * Microscopic algae * Some parasites Viruses are also studied in microbiology, although viruses are acellular, meaning they are not made of cells. Important idea Microbes are NOT automatically bad. Many microbes are harmless or helpful. They: * help produce food * live naturally in and on our bodies * help ecosystems function * can be used to make medicines and other products Only some microbes cause disease. 🍞 Humans Used Microbes Before They Knew Microbes Existed Humans were using microorganisms for thousands of years before microscopes existed. One of the biggest examples is: Fermentation Fermentation = microorganisms change sugars/carbohydrates into substances such as: * alcohol * gases * organic acids Microbes involved can include: bacteria + yeast + molds Humans used fermentation to make: * bread * cheese * yogurt * beer * wine * pickled vegetables Easy example Yeast eats/metabolizes carbohydrates in bread dough. ↓ Yeast produces carbon dioxide (CO₂). ↓ Gas becomes trapped in the dough. ↓ Bread rises. Remember Fermentation = microbes changing sugars. ⸻ 🧊 Ötzi the Iceman Ötzi was a preserved human mummy approximately 5,300 years old. Scientists found evidence that he had: * Trichuris trichiura → a parasitic worm * Borrelia burgdorferi → bacterium that causes Lyme disease He also carried a fungus called Fomitopsis betulinus, which has laxative and antibiotic properties. Why does this matter? It shows that ancient people were trying to treat disease long before they understood microorganisms. ⸻ 🦠 Early Ideas About Disease Before microscopes, people didn’t know exactly what caused disease. Some cultures believed disease came from: * supernatural forces * angry gods * fate * bad air But some people began to realize that disease might spread between people. ⸻ Quarantine Ancient societies sometimes separated sick people from healthy people. This is called: Quarantine = separating potentially infected people to prevent disease spread. Even though they didn’t know what bacteria or viruses were, they understood that some diseases could spread. ⸻ 🚿 Sanitation Ancient civilizations also developed ways to improve sanitation. Examples included: * clean-water systems * drainage systems * sewers * aqueducts This was important because removing human waste and providing cleaner water can reduce disease transmission. ⸻ Important People From Early Medicine Hippocrates Who? Greek physician. Important idea: Disease had natural causes, rather than always being caused by supernatural forces. He is commonly called: “Father of Western Medicine.” Remember Hippocrates → disease has natural causes. ⸻ Thucydides Thucydides survived the Athenian plague. He noticed that people who survived the disease usually did not become sick from the same disease again while caring for infected people. This was an early observation of: Immunity Immunity = the body’s ability to resist a particular infection/disease. Remember Thucydides → early idea of immunity. ⸻ Marcus Terentius Varro Varro proposed that extremely tiny creatures that could not be seen might cause disease. He described tiny creatures entering the body through the: * mouth * nose This was an important idea because microscopes did not yet exist. Remember Varro → invisible tiny creatures may cause disease. ⸻ Ibn Sina / Avicenna Ibn Sina wrote the important medical work: Canon of Medicine He described ideas involving: * contagion * spread of disease * transmission through breath * isolation of sick people His work contributed to ideas that later became important for quarantine and infectious-disease control. ⸻ 🔬 Birth of Microbiology The development of the microscope completely changed science. For the first time, scientists could actually see microorganisms. ⸻ Antonie van Leeuwenhoek Extremely important name. In 1675, Antonie van Leeuwenhoek used powerful simple microscopes to observe tiny organisms. He called them: “animalcules” Today we know that some of the organisms he observed were: * bacteria * protists Remember Leeuwenhoek → first to describe bacteria/microorganisms seen through a microscope. Think: Leeuwenhoek = LOOKED at microbes. ⸻ ⭐ Golden Age of Microbiology Approximately: 1857–1914 During this period, scientists made major discoveries connecting microorganisms with: * fermentation * disease * medicine * infection Two huge names: Louis Pasteur and Robert Koch You are going to see both names repeatedly in microbiology. ⸻ Louis Pasteur Pasteur showed that microorganisms are responsible for fermentation. He also developed: Pasteurization Pasteurization = using controlled heat to kill/reduce microorganisms that cause spoilage or disease. He also worked on vaccines, including a vaccine against: rabies Pasteur will become especially important again in Section 3.1. Remember Pasteur → fermentation → pasteurization → vaccines → helped prove germ theory → disproved spontaneous generation ⸻ Robert Koch Koch showed that particular microbes could cause particular diseases. He identified microorganisms associated with diseases including: * anthrax * tuberculosis * cholera Remember Koch → specific microbe → specific disease. ⸻ 🧪 Basic Microbiology Laboratory Tools You don’t need to master these yet, but recognize the terms. Microscope → magnifies microbes. Stains/dyes → add color/contrast so microorganisms are easier to see. Growth media → nutrients/material used to grow microorganisms in the laboratory. Petri dish → shallow dish commonly used to hold growth media. Test tube → can contain liquid or solid/semi-solid growth media. Bunsen burner → flame that can be used during laboratory sterilization procedures. These will make much more sense once you start doing microbiology lab work. ⸻ 1.2 A Systematic Approach Now we move from discovering microbes to: “How do scientists organize and name all these different organisms?” ⸻ Taxonomy Definition Taxonomy = classification, description, identification, and naming of living organisms. Think: Taxonomy = biological organization system. ⸻ Carolus Linnaeus Linnaeus developed an important system for classifying organisms. The main levels used in classification include: Kingdom → Phylum → Class → Order → Family → Genus → Species A common memory trick: K P C O F G S King Philip Came Over For Good Soup You should know the order. ⸻ Species Species is the most specific/basic taxonomic level in this hierarchy. Example: Homo sapiens Homo = genus sapiens = species ⸻ Binomial Nomenclature Very important term. Binomial = two names. Every organism receives a scientific name consisting of: Genus + species Example: Homo sapiens Rules: Genus * first letter CAPITALIZED species * lowercase Both should normally be italicized when typed. Correct: Homo sapiens Not: Homo Sapiens ❌ homo sapiens ❌ Homo Sapiens ❌ ⸻ 🌳 Phylogeny Phylogeny = evolutionary relationship/history between organisms. Scientists can represent these relationships with a: Phylogenetic tree A phylogenetic tree shows how organisms are believed to be evolutionarily related. Organisms with a more recent common ancestor are considered more closely related. ⸻ Classification Changed Over Time Scientific classification did not stay the same. Linnaeus Originally divided nature into kingdoms including: * animals * plants * minerals The mineral kingdom was later abandoned. ⸻ Ernst Haeckel Added: Protista for many unicellular organisms. He later proposed Monera for organisms lacking nuclei. Remember: Haeckel → Protista ⸻ Robert Whittaker Developed a five-kingdom system: Animalia Plantae Fungi Protista Monera ⸻ 🧬 Carl Woese — VERY IMPORTANT Carl Woese used differences in: ribosomal RNA (rRNA) to study evolutionary relationships. His work helped establish the modern: THREE-DOMAIN SYSTEM 🟠 Bacteria 🟣 Archaea 🔵 Eukarya This is very important for your Week 1 material. Memorize: BAE Bacteria Archaea Eukarya ⸻ Bergey’s Manuals These are important references used in bacteriology. They help scientists: * classify bacteria * identify bacteria You probably don’t need every detail yet, but recognize the name: Bergey’s Manual ⸻ How Can Bacteria Be Identified? Scientists can identify microorganisms using things such as: Biochemical tests Look at chemical/metabolic characteristics. DNA/RNA analysis Examines genetic material. Serological tests Use reactions involving antibodies/antigens. ⸻ 1.3 Types of Microorganisms This section is VERY IMPORTANT. You need to understand the major groups. ⸻ 🌎 Three Domains of Life Again: 1. Bacteria 2. Archaea 3. Eukarya ⸻ Before We Continue: Two Big Cell Types You will hear these words constantly: PROKARYOTE vs EUKARYOTE Prokaryotic cells DO NOT have a membrane-bound nucleus. Bacteria = prokaryotic Archaea = prokaryotic Eukaryotic cells DO have a membrane-bound nucleus. Examples include: * animals * plants * fungi * protozoa * algae Super important: Prokaryote = NO nucleus Eukaryote = HAS nucleus ⸻ 🦠 BACTERIA Bacteria are: * unicellular * prokaryotic * found almost everywhere Some bacteria are helpful. Some bacteria can cause disease. Many bacteria have cell walls. You’ll learn much more about bacterial structures later. ⸻ 🌋 ARCHAEA Archaea are also: * unicellular * prokaryotic Like bacteria, they do not have a nucleus. BUT: Archaea ≠ Bacteria They differ in: * genetics * evolutionary history * metabolic pathways * cell membrane composition * cell wall composition Archaea occur in many environments. Important textbook point No archaea have been identified as human pathogens. Remember Bacteria + Archaea = Prokaryotes ⸻ 🔵 EUKARYA Eukaryotic microorganisms include: Algae Protozoa Fungi Helminths These have eukaryotic cells. ⸻ 🌿 ALGAE Algae can be: * unicellular * multicellular They are similar to plants in an important way: They perform photosynthesis. Photosynthesis = using light energy to make chemical energy/food. Remember: Algae → photosynthesis. ⸻ 🧫 PROTOZOA Protozoa are: * unicellular * eukaryotic * structurally more complex than bacteria Many are capable of movement. Remember Protozoa → single-celled eukaryotes, often motile. Motile = able to move. ⸻ 🍄 FUNGI Fungi studied in microbiology include: Yeasts Usually unicellular. Molds Usually grow as multicellular filament-like structures. Examples of fungi can be microscopic even though other fungi, such as mushrooms, are large. Remember Fungi → yeast + molds ⸻ 🪱 HELMINTHS Helminths = parasitic worms. You may think: “A worm isn’t microscopic. Why is it in microbiology?” Good question. Adult worms may be large enough to see. BUT their: * eggs * larvae can be microscopic. Therefore they are studied in microbiology. ⸻ 🦠 VIRUSES Viruses are different from cellular organisms. Viruses are ACELLULAR. Acellular = not made of cells. Viruses cannot reproduce independently. They require a: Host cell to reproduce. Remember Virus = acellular + requires host to reproduce ⸻ ⭐ Major Microorganism Comparison Group Cell type Nucleus? Important idea Bacteria Prokaryotic ❌ Some cause disease Archaea Prokaryotic ❌ Different from bacteria; no known human pathogens Fungi Eukaryotic ✅ Yeasts + molds Protozoa Eukaryotic ✅ Unicellular, often motile Algae Eukaryotic ✅ Photosynthesis Helminths Eukaryotic ✅ Parasitic worms Viruses Acellular No cell Need host to reproduce 🔥 This table is worth knowing very well. ⸻ 3.1 Spontaneous Generation This is mainly about one historical question: Where does life come from? People once believed: Spontaneous Generation Spontaneous generation = the belief that living organisms can arise from nonliving material. Examples people once believed: rotting meat → maggots mud → frogs old food → microorganisms Today we know this idea is incorrect. ⸻ Francesco Redi Redi tested whether maggots appeared spontaneously from meat. He compared meat that flies could reach with meat protected from flies. Result Maggots appeared when flies could access the meat. This suggested: Maggots came from flies — not directly from the meat. Remember Redi → meat + flies + maggots ⸻ John Needham Needham performed experiments with broth. He boiled broth and then observed microbial growth afterward. He interpreted this as evidence supporting: Spontaneous generation. Remember Needham → supported spontaneous generation. ⸻ Lazzaro Spallanzani Spallanzani disagreed. He boiled broth for longer and sealed the containers more carefully. The sealed broth did not show microbial growth. He argued that microbes came from contamination from the environment rather than being generated spontaneously. Remember Spallanzani → argued against spontaneous generation. ⸻ 🦢 Louis Pasteur’s Swan-Neck Flask Experiment This is VERY IMPORTANT. Pasteur used flasks with long curved necks. Why the curved neck? Air could enter the flask. BUT: Dust and microorganisms became trapped in the curved neck. So the broth remained uncontaminated. When microorganisms could reach the broth, microbial growth occurred. Conclusion Microorganisms did NOT spontaneously appear. They came from microorganisms already present in the environment. Pasteur helped establish the principle: “Life comes from life.” Exam memory Pasteur → swan-neck flask → disproved spontaneous generation. ⸻ 3.2 Foundations of Modern Cell Theory Now we move from: “Where do microbes come from?” to: “What is life made of?” Answer: CELLS ⸻ 🧬 Cell Theory The textbook describes the development of the idea that cells are the fundamental units of life. The central ideas are: 1. All living organisms are made of one or more cells. 2. The cell is the fundamental/basic unit of life. 3. Cells arise from pre-existing cells. Think: Life → cells → cells come from cells. ⸻ Robert Hooke In the 1660s, Robert Hooke examined cork with a microscope. He saw tiny compartments and called them: “cells” Remember Hooke → named/described cells. Don’t mix him up with Leeuwenhoek: Hooke → cells Leeuwenhoek → microorganisms ⸻ Matthias Schleiden Schleiden studied plants. He concluded that: Plants are made of cells. Remember: Schleiden → plants ⸻ Theodor Schwann Schwann studied animals. He concluded: Animals are made of cells. Remember: Schwann → animals ⸻ Robert Remak Remak provided evidence that cells form through the division of existing cells. ⸻ Rudolf Virchow Virchow strongly promoted the idea: Cells come from other cells. So: New cells do not spontaneously appear. ⸻ Easy Scientist Memory Hooke → saw/named cells Schleiden → plants Schwann → animals Remak/Virchow → cells come from existing cells ⸻ 🧬 Endosymbiotic Theory This sounds difficult, but the basic idea is simple. Endosymbiotic theory says: Mitochondria and chloroplasts were originally bacteria-like prokaryotic cells. A larger ancestral cell engulfed them. Instead of being destroyed, the cells developed a mutually beneficial relationship. Eventually, the engulfed bacteria evolved into: Mitochondria and Chloroplasts inside eukaryotic cells. ⸻ Evidence for Endosymbiotic Theory Mitochondria and chloroplasts have similarities to bacteria. They have: Their own DNA Their DNA resembles bacterial DNA. Their own ribosomes Their ribosomes resemble bacterial ribosomes. They reproduce through a process similar to binary fission Binary fission is a major way bacteria reproduce. Easy version Mitochondria and chloroplasts act strangely like bacteria because their ancestors were bacteria. ⸻ Lynn Margulis Lynn Margulis helped develop and promote the modern endosymbiotic theory. Remember Margulis → endosymbiotic theory ⸻ 🦠 Miasma Theory vs Germ Theory This distinction is very important. Miasma Theory Old idea: Disease comes from “bad air” associated with rotting material. Think: Bad smell → disease. This theory was eventually replaced. ⸻ Germ Theory Germ theory = many diseases are caused by microorganisms. Think: Microbe enters/infects body → disease Scientists whose work helped establish germ theory included: * Ignaz Semmelweis * John Snow * Louis Pasteur * Joseph Lister * Robert Koch ⸻ 🧼 Ignaz Semmelweis Semmelweis worked around childbirth. He noticed that patients treated by doctors and medical students had much higher rates of puerperal fever than patients cared for by midwives. Medical students often went from: autopsies → examining living patients without washing their hands. Semmelweis introduced handwashing with chlorinated lime solution. Result Maternal deaths fell dramatically. Remember Semmelweis → HANDWASHING ⸻ 💧 John Snow John Snow investigated cholera outbreaks in London. He connected cholera cases with: contaminated water. His work helped show that disease wasn’t simply coming from “bad air.” He is important in the history of: Epidemiology Epidemiology = study of disease patterns and spread in populations. Remember Snow → cholera + contaminated water + epidemiology ⸻ Joseph Lister Lister applied ideas about microorganisms to surgery. He promoted: * handwashing * cleanliness * sterilization * antiseptic techniques He used carbolic acid (phenol) to reduce infections during surgery. Result Surgical infections decreased. Remember Lister → antiseptic surgery ⸻ Robert Koch — Again Koch developed: Koch’s postulates These helped scientists determine whether a particular microorganism causes a particular disease. Basic idea: specific microorganism → specific disease You will learn Koch’s postulates in more detail later. ⸻ 🔥 WEEK 1 — PEOPLE YOU NEED TO KNOW Scientist/person Remember THIS Hippocrates Disease has natural causes Thucydides Early observation of immunity Varro Invisible creatures may cause disease Leeuwenhoek Observed microbes/bacteria Linnaeus Taxonomy + naming organisms Haeckel Added Protista Whittaker Five kingdoms Woese Three domains; used rRNA Redi Meat + flies + maggots Needham Supported spontaneous generation Spallanzani Evidence against spontaneous generation Pasteur Swan-neck flask; fermentation; germ theory Hooke Described/named cells Schleiden Plants are made of cells Schwann Animals are made of cells Remak/Virchow Cells come from cells Margulis Endosymbiotic theory Semmelweis Handwashing John Snow Cholera + contaminated water Lister Antiseptic surgery Koch Specific microbes cause specific diseases ⸻ 🚨 THE 15 THINGS I WOULD MEMORIZE FIRST Don’t try to memorize every paragraph tonight. Start here: 1. Microbiology = study of microorganisms. 2. Fermentation uses microbes to convert sugars into products such as alcohol, gases, or acids. 3. Leeuwenhoek observed microorganisms. 4. Pasteur and Koch were major scientists during the Golden Age of Microbiology. 5. Taxonomy = classification and naming of organisms. 6. Binomial nomenclature = Genus + species. 7. Three domains = Bacteria, Archaea, Eukarya. 8. Bacteria + Archaea = prokaryotes. 9. Prokaryote = no membrane-bound nucleus. 10. Eukaryote = has membrane-bound nucleus. 11. Virus = acellular and needs a host to reproduce. 12. Spontaneous generation = life arises from nonliving matter. 13. Pasteur’s swan-neck flask helped disprove spontaneous generation. 14. Cell theory = organisms are made of cells, cells are the basic unit of life, and cells come from existing cells. 15. Germ theory = microorganisms can cause disease. ⸻ 🧠 Super-Simple Week 1 Mental Map Think about the entire week’s reading as one story: PART 1 — Humans discover microbes People used microbes before knowing they existed. ↓ Leeuwenhoek sees them. ↓ Scientists begin studying them. ⸻ PART 2 — Scientists organize microbes Linnaeus → Taxonomy ↓ Woese → 3 domains ↓ Bacteria | Archaea | Eukarya ⸻ PART 3 — Scientists ask where life comes from People believed in spontaneous generation. ↓ Redi + Spallanzani question it. ↓ Pasteur disproves it. ↓ Life comes from existing life. ⸻ PART 4 — Scientists understand cells Hooke → cells ↓ Schleiden → plants Schwann → animals ↓ Remak/Virchow → cells come from cells ↓ Cell Theory ⸻ PART 5 — Scientists understand disease Old: Miasma = bad air causes disease ❌ ↓ New: Germ theory = microorganisms can cause disease ✅ ↓ Semmelweis → handwashing Snow → contaminated water Lister → antiseptic surgery Pasteur → microbes Koch → specific microbe causes specific disease
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Unit 3 Northwest Territory: Location - The region south of the Great Lakes, north and west of the Ohio River, and east of the Mississippi River (modern-day Ohio, Indiana, Illinois, Michigan, and Wisconsin) Settlement expectations - Orderly Grid System: Land was grid-surveyed into square townships (36 square miles) to prevent chaotic land claims. Section 16 of each township was reserved to fund public education. Path to Statehood: Established a 3-stage process for territories to achieve statehood on equal footing with the original 13 states once they reached 60,000 free inhabitants. Civil Liberties & Prohibitions: Guaranteed trial by jury and freedom of religion. Crucially, it banned slavery north of the Ohio River, setting the first federal geographic boundary on the institution. Articles of Confederation: structure of government - A unicameral (one-house) legislature. There was no executive branch (no president to enforce laws) and no national judiciary to settle interstate legal conflicts. importance of Congress - Congress was the sole body of national power. Each state received exactly one vote, meaning small states held equal power to large states Weaknesses - No power to tax: Congress could only request money from states. No power to regulate commerce: Led to interstate tariff wars. Rigid thresholds: Passing major laws required a 9/13 supermajority; amending the Articles required a 13/13 unanimous vote. No standing national army: Left the government defenseless against foreign threats or domestic rebellion. Shay’s Rebellion: Causes - Western Massachusetts farmers (many Revolutionary War veterans) faced heavy state taxes, severe post-war economic depression, and foreclosures on their farms by coastal merchants and courts. Led by Daniel Shays, they shut down debt courts. Outcomes - The weak central government was unable to raise an army to suppress the rebellion; a privately funded state militia finally stopped it. This exposed the profound weaknesses of the Articles of Confederation, spreading fear of "mobocracy" among elites and directly prompting the Constitutional Convention of 1787. Whiskey Rebellion: Causes - Poor western Pennsylvania farmers protested an excise tax on whiskey enacted by Treasury Secretary Alexander Hamilton to pay off national war debts. Whiskey was used as currency and a primary way to market surplus grain. Unique elements - Unlike Shays' Rebellion, President George Washington invoked his new constitutional powers and personally led a massive federalized militia of 13,000 troops to crush the insurrection. Effects - Demonstrating the immense contrast with Shays' Rebellion, it proved that the new federal government under the Constitution possessed the executive power to enforce federal laws and suppress domestic insurrections. It solidified federal authority but alienated westerners, bolstering the nascent Democratic-Republican opposition. Structure of US Government under Constitution – separation of power - Legislative (makes laws), Executive (enforces laws), and Judicial (interprets laws) checks and balances - A system allowing branches to limit the actions of others. Examples: The President can veto congressional legislation; Congress can override a veto or impeach the President; the Senate must approve judicial nominations. Federalism - The constitutional division and sharing of political power between the national (federal) government and the individual state governments. popular sovereignty - The principle that political power resides with the people, who sustain government legitimacy through consent via elected representatives. supremacy clause - Article VI; Establishes that the U.S. Constitution, federal laws, and treaties constitute the "supreme law of the land," overriding conflicting state laws. Issue of slavery: who supported - Southern delegates (e.g., South Carolina, Georgia) fiercely protected slavery as vital to their agrarian, plantation economies. who opposed - Many Northern delegates opposed slavery or its expansion, but prioritized national unity and economic concessions over immediate abolition. position taken by the Founders - The Founders chose pragmatic compromise over moral resolution to keep the Southern states in the Union. They conspicuously avoided using the words "slave" or "slavery" in the text but protected the institution through: Three-Fifths Compromise: Counted 60% of a state’s enslaved population for both congressional representation and federal taxation. Slave Trade Clause: Prohibited Congress from banning the international slave trade for 20 years (until 1808). Fugitive Slave Clause: Required free states to return escaped enslaved laborers to their owners. Concepts debated by Federalist and Anti-Federalists during and after Washington’s presidency; be familiar with people associated with each party Era/Context Federalists Anti-Federalists/Democratic-Republicans Ratification Debate (1787-1788) Supported the Constitution. Wanted a strong central government to maintain order. Written defenses: The Federalist Papers. Opposed the Constitution. Feared a strong central government would mimic British tyranny and squash individual rights. Demanded a Bill of Rights. First Party System (1790s) Federalist Party Democratic-Republican Party Key Leaders Alexander Hamilton, John Adams. Thomas Jefferson, James Madison. Constitutional Interpretation Loose constructionism (broad use of the "elastic/necessary and proper" clause). Strict constructionism (the federal government only has powers explicitly stated in the Constitution). Core Vision Urban, commercial, manufacturing hub; pro-British foreign policy; favored a National Bank. Agrarian republic of independent farmers; pro-French foreign policy; opposed the National Bank. John Adams’ Domestic and Foreign Policy – Naturalization Act, Alien and Sedition Acts, XYZ Affair XYZ Affair (1797): French privateers began seizing American merchant ships. Adams sent diplomats to Paris, where three French agents (dubbed X, Y, and Z) demanded massive bribes before negotiating. This sparked anti-French outrage across America and triggered the Quasi-War, an undeclared naval war. Naturalization Act (1798): Increased the residency requirement for American citizenship from 5 to 14 years. This was designed to target French and Irish immigrants, who heavily voted Democratic-Republican. Alien and Sedition Acts (1798): Alien Act: Authorized the president to deport any non-citizen deemed dangerous to national peace. Sedition Act: Made it a crime to publish "false, scandalous, and malicious writing" against the government or its officials. Adams used it to jail Democratic-Republican newspaper editors. Marbury v. Madison, McCullough v. Maryland Marbury v. Madison (1803): Chief Justice John Marshall ruled that a section of the Judiciary Act of 1789 conflicted with the Constitution. This established the doctrine of Judicial Review, cementing the Supreme Court's power to declare federal laws unconstitutional. McCulloch v. Maryland (1819): Maryland attempted to tax the Second Bank of the United States. The Marshall Court ruled that: The Bank was constitutional via the Implied Powers of the Necessary and Proper Clause. States cannot tax federal institutions ("the power to tax involves the power to destroy"), reaffirming Federal Supremacy. Short Answer: (These are all straight from google overview, just as an fyi) a) Explain the concerns for the nation Washington expressed in his Farewell Address and how they became issues during and immediately following his terms in office. In his 1796 Farewell Address, George Washington explicitly warned the young nation against two main existential threats: the rise of factions (political parties) and entering into permanent foreign alliances. Despite his warnings, both issues immediately fractured the nation during and after his presidency. Domestically, the fierce ideological rift between Alexander Hamilton’s Federalists and Thomas Jefferson’s Democratic-Republicans hardened into America’s first permanent political party system. Externally, the ongoing geopolitical conflict of the French Revolution forced America to take sides. While Washington issued a Neutrality Proclamation in 1793, foreign entanglements escalated under John Adams, whose administration was consumed by the XYZ Affair and the resulting Quasi-War with France. b) Evaluate the issues associated with Adams’ Alien and Sedition Acts. The primary constitutional and political issue of the Alien and Sedition Acts of 1798 was their weaponization for partisan suppression, which directly violated civil liberties. The Sedition Act explicitly restricted freedom of speech and the press by criminalizing criticism of the federal government, drawing widespread condemnation for violating the First Amendment. Furthermore, Federalists utilized these acts to aggressively target their political opponents, arresting Democratic-Republican editors who criticized Adams’ anti-French foreign policies. In response to this perceived federal tyranny, Thomas Jefferson and James Madison anonymously penned the Virginia and Kentucky Resolutions. These documents introduced the radical constitutional theory of nullification, arguing that sovereign states had the right to declare federal laws null and void within their borders, setting a dangerous precedent for future states' rights crises. LEQ – Be able to analyze the 4 areas of concern presented at the Constitutional Convention, including the arguments made by Federalists and Anti-Federalists, as well as the agreements reached that were included in the Constitution. Thesis Statement: Although delegates at the Constitutional Convention of 1787 originally gathered to revise the weak Articles of Confederation, deep regional divides over representation, state power, and economic structure forced intense debates between Federalists and Anti-Federalists. Ultimately, the framework of the new Constitution succeeded because delegates forged pragmatic compromises over congressional representation, executive authority, the preservation of slavery, and federal taxes. Area of Concern 1: Congressional Representation (Large vs. Small States) Debate: Large states favored the Virginia Plan (proportional representation based on population); small states demanded the New Jersey Plan (equal representation per state). Agreement: The Great Compromise (Connecticut Compromise) established a bicameral legislature. The House of Representatives based representation on population, while the Senate granted two seats per state. Area of Concern 2: Counting the Population (Northern vs. Southern States) Debate: Southern states demanded enslaved individuals be counted to boost their legislative seat totals but excluded for federal tax purposes. Northern states argued this was unjust since enslaved populations lacked civil rights. Agreement: The Three-Fifths Compromise dictated that three out of every five enslaved individuals would be counted for both representation and taxation. Area of Concern 3: Executive Branch Power Debate: Anti-Federalists feared a strong executive would morph into a monarchy. Federalists argued a strong executive was vital to enforce laws and avoid the chaos seen in Shays’ Rebellion. Agreement: The creation of a single executive (the President) checked by congressional override powers, impeachment processes, and elected indirectly via the Electoral College. Area of Concern 4: Central Power vs. Individual Rights (The Ratification Pivot) Debate: Anti-Federalists refused to ratify the document because it centralized immense power under the Supremacy Clause without explicitly protecting individual liberties. Federalists argued that separation of powers inherently protected individuals. Agreement: Federalists promised to add a Bill of Rights immediately upon ratification, which James Madison drafted during the First Congress to safeguard civil liberties against federal overreach.
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