17. Ethylene glycol poisoning

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6 Terms

1
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Where ethylene glycol found?

In antifreeze

2
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Is ethylene glycol harmful?

Not poisonous itself -> when broken down in liver by enzyme dehydrogenase

3
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What is toxic?

Break down of product (oxalic acid)

4
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What is the break down of product (oxalic acid)

Extremely toxic

5
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What happens if they think someone has had ethylene glycol?

Patient given massive dose of ethanol (alcohol)

6
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Why is the patient given ethanol?

Acts as competitive inhibitor for alcohol dehydrogenase -> Reduces production of oxalic acid -> Allows ethylene glycol to be excreted harmlessly