amino acid change

gene

region of DNA that produces functional product (polypeptide)

allele

different versions of a gene

gene studied

MSH6

alleles of MSH6

different versions of MSH6

codons

3 nucleotide sequences in mRNA that specify particular amino acid

start codon

specifies the first amino acid in polypeptide sequence

what is the usual amino acid for start codon in eukaryotes

methionine

stop codon

specifies end of polypeptide synthesis

what can affect the amino acid sequence of a protein

single nucleotide change

what does the change in amino acid sequence affect

can affect the structure of(shape) and function of protein