Chronic Degenerative Disorders

Describe ***Multiple Sclerosis***

Progressive Irreversible @@**Demyelination**@@ of the (Axon Myelin Sheath) @@Brain and Spinal Cord@@

* Unknown Causes
* Common in White women in Mild Climates
* @@Fatigue@@
* @@NO CURE@@
* @@Quality of Life@@ Issues - Depression & Anxiety

Describe ***Parkinson’s Disease***

* **T.R.A.P.**

Destruction of the @@***Substantia Nigra***@@ in the Brain Resulting @@***Lack of Dopamine***@@

* Hand & Head @@**Tremors**@@
* @@**Rigidity**@@- Resistan ROM
* @@**Akinesia**@@ - loss of voluntary Muscle Movement
* @@**Postural Disturbance**@@ - Torso moving Back and Forth causing falls. Stooped
* Prevalent in Elderly Men

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Describe ***ALS (Amyotrophic Lateral Sclerosis)***

@@__**Nerves lose ability to Trigger Muscle Movement**__@@ due to @@__**Damage**__@@ of Upper & Lower @@**Motor Neurons**@@ of the the Cerebral Cortex and Brain Stem/ Spinal Cord

* Muscle @@Weakness and Atrophy@@ caused by @@Motor Neuron Loss@@
* @@Foot-Drop@@

Describe ***Myasthenia Gravis***

**Acetylcholine Receptors** are **Impaired**/Destroyed by **IgG Autoantibodies**

* disruption of Communication at the @@__**Neuromuscular Junction**__@@
* Risk Factor - @@__**Thymus Abnormality**__ __**& Tumors**__@@
* Vision and Eyelid Problems
* Myasthenia Crisis - Muscles become Too Fatigued to maintain Ventilation

Describe ***Huntington’s*** ***Disease***

__**Movement disorder**__ with Abnormal Upper Body Movement and __**Mood Swings**__

* __**Writhing**__ - Twisting Movement of Face, Limbs, and Body
* Death due to Infection __**(Pneumonia)**__
* **Suicide**

Describe Alzheimer’s

__**Loss of Memory**__ and Thinking due to __**Loss of Neuron Connection, Neurofibril Tangles, Amyloid Plaques**__