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Biology
scientific study of life
Science
is an approach to understanding the natural world that is based on inquiry
inquiry
a search for information, evidence, explanations, and answers to specific questions
what does biology begin with?
observation & exploration
observe
to watch the subject & record your observations
data
Recorded observations
scientific questions leads to…
testing
what makes a good question?
Answerable
Often ”why?”
Testable
Based on what is already known
Repeatable
When answered often lead to further questions…
hypothesis
a tentative answer to a well-framed scientific question
a proposed explanation for a set of observations
hypothesis is usually
a rational accounting for a set of observations
results of an experiment
will either support or not support the hypothesis. There is no “proving” or being “correct” in science
Scientists rely on
scientific literature to formulate questions
Scientists communicate
findings with each other with seminars, meetings, and scientific publications
before publishing in a scientific journal they go through
peer review
peer review
research is evaluated by qualified, impartial, & anonymous experts who were not involved in the study
fact
is a piece of information considered to be objectively true based on all current evidence
theory
a comprehensive and well-substantiated explanation
Law
a statement usually using math based on repeated experiments
Pseudoscience
any field of study that is falsely presented as having a scientific basis
How to detect pseudoscience
may be based solely or largely on anecdotal evidence
anecdotal evidence
an assertion based on a single or a few examples that do not support a generalized conclusion
features of science
Adheres to an established and well-recognized scientific method
Repeatable results
Testable claims that can be disproven
Open to outside review
Multiple lines of evidence
features of Pseudoscience
Does not adhere to generally accepted processes of science
Results that cannot be duplicated by others;results that rely on a single person or are solely opinion
Unprovable or untestable claims; reliance on assumptions or belief that are not testable
Rejection of external review or refusal to accept contradictory evidence
Overreliance on a small amount of data; underlying causes are not investigated
Variables
factors that change in an experiment
controlled experiment
compares two or more groups that differ only in one variable
control group
acks or does not receive the specific factor being tested
experimental group
has or receives the specific factor being tested
independent variable
what is being manipulated by the researchers as a potential cause
dependent variable
the response, output, or effect under investigation that is used to judge the outcome of the experiment
placebo
Many medical drug trials include
Double-blind experiment
in which neither the participant nor the experimenter knows which group is the control group
Structure & Function
At different levels within biological systems: Within molecules, cells, tissues, and organs
Information Flow
necessary at all levels of biological organization
Life’s Processes involve the expression and transmission of genetic information
DNA
Movement, growth, reproduction, and cellular activities of life are
work
DNA (deoxyribonucleic acid)
Heredity (inheritable)
Stored in chromosomes
Contains genes
Programs cell
Blueprint for proteins
Work
Energy
Sun energy
major input, lost as heat energy
Sunlight
captured by photosynthetic organisms (producers)
consumed by consumers
This energy is converted into chemical energy, & stored as chemical bonds within sugars
Within all living cells
network of chemical reactions (metabolism) continually converting energy from one form to another
Energy transformations
can be disrupted often with dire consequences
Interactions
occur on the cellular to global level
At each level of interactions
complexity increases & novel properties emerge that are absent from the preceding one
emergent properties
are due to the specific arrangement & interactions of many parts into an increasingly complex system
evolution
Life is distinguished by its unity and its diversity
the process of change that has transformed life on Earth
lines of evidence of evolution
the similarities among fossil & living organisms
the common cellular processes
the universal chemical structure of DNA
theory of evolution by natural selection
Charles Darwin published: On the Origin of Species by Means of Natural Selection:
1. Species living today arose from a succession of ancestors that were different from them in a process Darwin called "descent with modification."
2. The process of natural selection is the driving force of evolution
Evolution by Natural Selection
Individuals with traits best suited to the local environment are more likely to survive and leave the greatest number of healthy offspring. This unequal reproductive success is because the environment "selects" only certain heritable traits from those already existing
occurs on a POPULATION level
Matter
anything that occupies space and has mass
All organisms are composed of
made up of elements
cannot be broken down to other substances
Mass
a measure of the amount of material in an object
Element
a substance that cannot be broken down into other substances by chemical reactions
all matter
is composed of chemical elements
Trace element
are required by an organism in only minute quantities
25 elements are essential for human life
4 elements (Oxygen, Carbon, Hydrogen and Nitrogen) make up 96% of most living organismsCompounds
Compounds
made up of two or more different elements in a fixed ratio
Atoms
Each element consists of one kind
smallest unit of matter that still retains the properties of an element
made of electrons, protons, and neutrons
Neutrons
no charge
electrons
negative charge
protons
positive charge
Isotopes
have the same number of protons and behave identically in chemical reactions, but they have different numbers of neutrons
atom’s mass number
sum of the number of protons & neutrons in its nucleus
element’s atomic number
All atoms of a particular element have the same unique number of protons
radioactive isotope
which the nucleus decays spontaneously
Radioactive decay
can be used to obtain important data about the evolutionary history of life on Earth
fossils
reliable chronological records of life
age can be estimated by measuring the ratio of the two isotopes to learn how many half-life reductions have occurred since it died
With radioactive dating scientists can estimate the ages of it & place them
radioactive dating
scientists can estimate the ages of fossils & place them in fossil records
fossil record
ordered sequence
chemical reactions
Only electrons are directly involved in it
The number of electrons in an atom determines
the chemical properties of that atom
Chemical reactions enable
atoms to transfer or share electrons.
chemical bonds
enabling atoms to transfer or share electrons usually result in atoms staying close together
Covalent bonds
forms when two atoms share one or more pairs of electrons
are the strongest of the various bonds
hold atoms together in a molecule
Ionic Bonds
formed between oppositely charged ions
ions
atoms or molecules that are electrically charged as a result of gaining or losing electrons
Atoms sometimes
strip electrons from their bonding partners
hydrogen bonds
polarity of water results in weak electrical attractions
chemical reactions
changes in the chemical composition of matter
Cells constantly rearrange molecules
can rearrange matter but cannot create or destroy matterwate
reactants
the starting materials
products
the end materials
water
Life on Earth began in water
Life evolved 3 billion years before spreading onto land
The abundance of water is a major reason that Earth is habitable
The polarity of water molecules and the hydrogen bonding that results explain most of water’s life-supporting properties
How do water molecules stick together?
hydrogen bonding
Cohesion
the tendency of molecules of the same kind to stick together
much stronger for water than for most other liquids
surface tension
a measure of how difficult it is to stretch or break the surface of a liquid.
hydrogen bonds makes water unusually high
Ice floats
it is less dense than the liquid water in which it is floating
Floating ice
acts as an insulating “blanket” over liquid water, allowing life to persist under the frozen surface
solution
liquid consisting of a homogeneous mixture of two or more substances
solvent
the dissolving agent
solute
the dissolved substance
Acid
a chemical compound that releases H + to a solution
Base
a compound that accepts H+ & removes them from solution
To describe the acidity of a solution chemists use this
PH scale
pH scale
a measure of the hydrogen ion H + concentration in a solution
Buffers
minimize changes in pH
cells
mostly water
The rest, mainly of carbon-based molecules
Carbon
forms large, complex, and diverse molecules necessary for life’s functions
can share electrons with other atoms in four covalent bonds
Organic compounds
carbon-based molecules
can also bond with other elements, most commonly hydrogen, oxygen, and nitrogen
depend on its carbon skeleton and the atoms attached to the skeleton
functional groups
the groups of atoms directly involved in chemical reactions as part of organic compound
Many biological molecules have two or more
Polymers
large macromolecules made by stringing together many smaller molecules called monomers
dehydration reaction
links two monomers together &
removes a molecule of water
link nucleotide monomers into long chains called polynucleotides form covalent bonds between the sugar of one & the phosphate of the next
Hydrolysis
breakdown of polymers occurs by adding water to them, a process that is essentially the reverse of a dehydration reaction
Macromolecule
a very large molecule important to biological processes
4 categories