Central Nervous System (CNS) and Peripheral Nervous System (PNS)
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Central Nervous System is made up of
brain and spinal column
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Peripheral Nervous System is made up of
cranial and spinal nerves
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2 major divisions of the peripheral nervous system
Sensory (afferent) division
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Motor (efferent) division
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Sensory (afferent) division
Nerve fibers that carry information to the central nervous system
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- pick up information from sensory receptors
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Motor (efferent) division
Transmits impulses from the CNS to effector organs (muscles and glands)
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Motor (efferent) division is divided into (2)
somatic nervous system and autonomic nervous system
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somatic nervous system
the division of the peripheral nervous system that controls the body's skeletal muscles
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- carries information to skeletal muscle
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autonomic nervous system
the part of the peripheral nervous system that controls the glands and the muscles of the internal organs (such as the heart).
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- carries information to smooth muscle
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neuron labeled
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white matter
Whitish nervous tissue of the CNS consisting of neurons and their myelin sheaths.
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What forms white matter?
scwann cells and oligodendricytes
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- inside deep tissue of brain, outside spinal cord, myelinated
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gray matter
Brain and spinal cord tissue that appears gray with the naked eye; consists mainly of neuronal cell bodies (nuclei) and lacks myelinated axons.
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- unmyelinated
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Where on a neuron do you find chemically gated channels?
Dendrites and cell body
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What causes the chemically gated channels to open? What comes out?
Opened by the binding of neurotransmitters to the channel
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- sodium in, potassium out
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Where on a neuron do you find voltage gated channels?
Axon
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What causes them to open? What moves through the channels?
Opened by changes in membrane potential --\> depolarization
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- sodium comes out
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resting membrane potential
the electrical charge of a neuron when it is not active
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-70mv
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How can a neuron go from resting membrane potential to threshold?
Depolarization occurs (-55 to -50 mV), at threshold, depolarization becomes self-generating
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How action potential is generated
If a receptor is a neuron and the change in membrane potential reaches threshold an action potential is generated
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- membrane becomes more permeable to sodium ions b/c of the opening of sodium voltage gated channels causing RAPID/SUDDEN influx of sodium and depolarization of membrane
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How a cell returns back to resting membrane potential
The activation gate of Na+ voltage gated channels are closed, K+ voltage gated channels close, K+ flows out of cell
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What does the sodium-potassium pump do for a neuron?
Restores ionic conditions
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- pumps 3 sodiums in per every 2 potassium that enter
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What affects the conduction velocities amongst neurons?
Influenced by myelin sheath thickness and internode distance
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What are the different types of neurotransmitters?
-acetylcholine
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-biogenic amines (catecholamines and indolamines)
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-amino acids (GABA, glycine, aspartate, and glutamate)
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-neuropeptides
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-purines such as ATP
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-novel messengers
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How are neurotransmitters broken down or removed from the system?
Removed by diffusion in combination with re-uptake into nerve terminals/ surrounding glial cells, degradation by transmitter or a combination
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Meninges (3)
dura mater, arachnoid mater, pia mater
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Dura mater
thick, outermost layer of the meninges surrounding and protecting the brain and spinal cord
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arachnoid mater
weblike middle layer of the three meninges
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pia mater
the delicate innermost membrane enveloping the brain and spinal cord.
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Ventricles of the brain
2 lateral ventricles, third ventricle, fourth ventricle
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How do the ventricles of the brain relate to the CSF
They are interconnected cavities that are continuous with central canal of spinal cord filled with CSF- cerebrospinal fluid.
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- It is a clear liquid that completely surrounds the brain and spinal cord
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- nutritive and protective
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What are the functions of the spinal cord?
sends motor commands from brain to the body, sends sensory information from the body to the brain, coordinates reflexes, spinal reflexes
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What are the functions of the brain?
- interprets sensations
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- determines perception
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- stores memory
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- reasoning
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- makes decisions
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- coordinates muscular movements
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- regulates visceral activities
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- determines personality
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What are the functions of the cerebrum?
-Interprets impulses from sense organs
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-Initiates voluntary muscular movement
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-Stores information as memory
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-Reasoning, intelligence, personality
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identify lobes of the brain
insula- between frontal and temporal
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cutaneous sensory area
-parietal lobe
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-interprets sensations on skin
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visual area
occipital lobe, interprets visual information
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auditory area
temporal lobe, interprets auditory information
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Sensory area for taste
Near base of the central sulcus
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Includes part of insula
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Sensory area for smell
arises from centers deep within temporal lobes
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What do association areas do?
- analyze and interpret sensory experiences
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- help provide memory
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- reasoning
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- verbalizing
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- judgement
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- emotions
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Things controlled by left hemisphere
- writing
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- reading
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- verbal skills
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- analytical
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- computational skills
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Things controlled by right hemisphere
- nonverbal/ motor tasks
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- understanding and interpreting music/visual patterns
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- provides emotional and intuitive thought processes
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How are short term memories converted into long term memories
memory consolidation: repeated stimulation causes changes in structure/ functions of neurons
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short-term memory
- working memory
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- closed neuronal circuit
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- impulse flow ceases, memory ceases.
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long-term memory
- changes structure and function of neurons
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- enhances synaptic transmission
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What do motor areas do?
generate signals to direct the movement of the body