Support and ANCHOR neurons to surrounding capillaries, giving blood to surrounding tissues
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Microglia
Provide immune response to to CNS
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Meningitis
Meninges infection, microglia help
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Ependymal cells
Secrete and circulate cerebrospinal fluid
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Oligodendrocytes
Provide myelin insulation to neurons in the Central Nervous System.
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Neuroglial cells in the Peripheral Nervous System
Satellite cells, Schwann cells
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Satellite cells
SUPPORT and anchor neurons in the PNS.
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Schwann cells
Provide myelin insulation to neurons in the PNS.
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What is a nerve impulse
An electrical signal that travels along a neuron
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How do nerve impulses arise
It arises from a movement of ions causing a change in electrical charges.
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How is intracellular space charged?
Negatively charged (resting potential)
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How is extracellular space charged?
Positively charged (resting potential)
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What happens when a neuron is stimulated by the environment or another neuron?
Sodium rushes into the neuron, and quickly reverses the charges (Depolarization), this process quickly moves down the length of a neuron.
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What is depolarization known as?
Action potential
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What happens as the impulse passes?
Potassium diffuses out of the neuron (Repolarization)
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Refractory period
Spike down caused by ions moving back to original spots
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What does sodium potassium pump do after repolarization?
Restores ion concentrations to normal, resting potential returns. (All or Nothing event) → Homeostasis
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What are some problems with the Na K pump if it doesn’t work?
Congestive heart failure
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Synapse
Where two neurons meet
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Synaptic cleft
The space between the two neurons at a synapse because the neurons don’t touch.
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What happens when an impulse reaches the axon terminal?
It can’t cross the gap between the two neurons, so it stimulates vesicles to release neurotransmitters across the synaptic cleft.
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How do neurotransmitters open the next neuron?
They cause channels to open, continuing the action potential from one neuron to the next.
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What is an example that uses this process?
When you take drugs that cause hormones to be released like Caffiene.
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What chemical helps impulses travel?
Calcium ions
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What are the 3 layers of connective tissue that protect the brain and spinal cord called? (blood-brain barrier)
Meninges
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Layers of meninges from top to bottom
Skin, Periosteum, Bone, Dura Mater, Arachnoid Membrane, Pia Mater
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Dura mater
Thick, tough layer
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Arachnoid membrane
Thin, cobweb-like layer
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Pia Mater
Thin layer containing lots of blood vessels
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What is between the Arachnoid layer and the pia mater?
Cerebrospinal Fluid (CSF)
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What does the cerebrospinal fluid do
Protects the brain by preventing it from contacting the skull & maintains the blood brain barrier.
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What does the blood brain barrier do?
Controls homeostasis for the brain and prevents infection.
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Where is CSF produced
Spaces within the brain called ventricles
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What are the four ventricles?
Lateral (Right and Left), 3rd and 4th ventricles.
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How are the lateral ventricles connected to the third ventricle?
The thin interventricular (inter= between ventricles) foramen → Foramen of Monro (hole)
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What are choroid plexuses
Clusters of capillaries in the ventricles that secrete CSF, causing it to flow around the ventricles, then be absorbed by arachnoid granulations in the blood.
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What is CSF constantly doing in the ventricles?
Being produced, circulated, and reabsorbed. (Continuously and closed)
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Cerebrum
Largest part of the brain, divided into two hemispheres (right and left)
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How are the two hemispheres of the brain connected?
A bundle of nerve fibers called the corpus callosum.
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What is the surface of the cerebrum covered with?
Ridges (gyri) and grooves (sulci)
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What are the deep grooves that divide portions of the brain?
Fissures
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What are the brain’s 3 major layers from superficial to deep?
Cerebral cortex, cerebral medulla, basal nuclei
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Cerebral cortex
Gray matter, made of cell bodies and dendrites
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Cerebral medulla
White matter, made of myelinated axons.
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Basal nuclei
Islands of gray matter
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How is the cerebrum divided?
It is divided into 4 lobes based on their functions, and are named for parts of the skull protecting them.
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Frontal lobe
Controls voluntary movements like walking, reasoning + decision making. memory, predicting consequences. planning, verbal communication in Broca’s area
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How is the frontal lobe separated from the parietal lobe?
The central sulcus
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Parietal lobe
Sensations like pain, temperature, and touch, visual spatial processing and body position.
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Occipital lobe
Visual processing, vision and memory of objects.
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How is the temporal lobe separated from the frontal lobe?
Lateral sulcus
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Temporal lobe
Controls memory, comprehension and pronunciation of words. smell and sound, emotional association of memories.