The nervous system is divided into
Central Nervous System and Peripheral Nervous System
Function of the Nervous System
Master control center for the body, detects impulses from the center
Central Nervous System
Brain and spinal cord
Peripheral Nervous System
Cranial Nerves and Spinal Nerves not in brain/spinal cord
Cranial Nerves
Originate in the brain, 12 to help control body
Spinal Nerves
Originate in the spinal cord
Peripheral Nervous System is divided into
Sensory (Afferent) Division and Motor (Efferent) Division
Sensory (Afferent) Division
Sends impulses from the senses AT the CNS
Motor (Efferent) Division
Sends impulses from the CNS to the muscles and glands (EXITS)
The Motor division divides into the
Autonomic and Somatic Nervous System
Autonomic Nervous System
Involuntary muscle control like digestion, urination, heart pumping
Somatic Nervous System
Voluntary muscle control like muscular skeletal movements
The Autonomic Nervous System is divided into the
Sympathetic and Parasympathetic Divisions
Sympathetic Division
Used in emergency situations, fight or flight response
Parasympathetic Division
Reduces the sympathetic response, provides resting functions such as digestion and urination.
Effects of an activated Sympathetic/fight or flight
Heart rate and breathing rate increase, blood pumped to the extremities for physical activities and is diverted from organs
What system does the nervous system work with?
The Endocrine System
For the nervous system to do its job it uses
Sensory input, integration, and response
Sensory input
Detects changes/stimuli inside and outside of the body
Integration
Processing and interpreting the information
Response
Activation of muscles (motor output) or glands
The 2 major types of nerve cells are
Neurons and neuroglia
Neurons
Conduct impulses around the body, make up 10% of nerve cells
Neuroglia
Act as nerve glue & support, insulate, and protect neurons, make up 90% of nerve cells
What do all neurons have in common?
A main cell body and processes extending outward.
The cell body contains the
Nucleus, cytoplasm, organelles
Processes of a neuron are divided into
Dendrites and Axons
Dendrites
Bring impulses TOWARDS the cell body
Axons
Send impulses AWAY from the cell body
What do processes end with?
Axon terminals
Axon terminals
Release neurotransmitters to pass the impulse to the next neuron
MS disease
Myelin sheath degenerates, motor function issue
Neurons are classified by
number of processes extending from the cell body and their function
One process
Unipolar neurons
Two processes
Bipolar neurons
many processes
Multipolar neurons
Afferent neurons
Carry impulses AT the CNS
Efferent neurons
Carry impulses away from the CNS (EXITS)
Interneurons
Connect afferent and efferent neurons.
What are axons wrapped in?
Myelin, which is like a waxy insulation.
How is myelin formed?
Schwann cells (type of neuroglia) wrap itself around the axon, like a coil, helping it move faster with support and protection.
Neurilemma
Outer layers of the Schwann cell
What does myelin do?
Helps the nerve impulses to travel more quickly.
Myelin sheath
All of the myelin wrappings collectively.
Nodes of Ranvier
Gaps formed because the myelin sheath has many Schwann cells.
Where are Neuroglial cells found
In both the CNS and PNS.
Neuroglial cells in the CNS
Astrocytes, Microglia, Ependymal cells, oligodendrocytes
Astrocytes
Support and ANCHOR neurons to surrounding capillaries, giving blood to surrounding tissues
Microglia
Provide immune response to to CNS
Meningitis
Meninges infection, microglia help
Ependymal cells
Secrete and circulate cerebrospinal fluid
Oligodendrocytes
Provide myelin insulation to neurons in the Central Nervous System.
Neuroglial cells in the Peripheral Nervous System
Satellite cells, Schwann cells
Satellite cells
SUPPORT and anchor neurons in the PNS.
Schwann cells
Provide myelin insulation to neurons in the PNS.
What is a nerve impulse
An electrical signal that travels along a neuron
How do nerve impulses arise
It arises from a movement of ions causing a change in electrical charges.
How is intracellular space charged?
Negatively charged (resting potential)
How is extracellular space charged?
Positively charged (resting potential)
What happens when a neuron is stimulated by the environment or another neuron?
Sodium rushes into the neuron, and quickly reverses the charges (Depolarization), this process quickly moves down the length of a neuron.
What is depolarization known as?
Action potential
What happens as the impulse passes?
Potassium diffuses out of the neuron (Repolarization)
Refractory period
Spike down caused by ions moving back to original spots
What does sodium potassium pump do after repolarization?
Restores ion concentrations to normal, resting potential returns. (All or Nothing event) → Homeostasis
What are some problems with the Na K pump if it doesn’t work?
Congestive heart failure
Synapse
Where two neurons meet
Synaptic cleft
The space between the two neurons at a synapse because the neurons don’t touch.
What happens when an impulse reaches the axon terminal?
It can’t cross the gap between the two neurons, so it stimulates vesicles to release neurotransmitters across the synaptic cleft.
How do neurotransmitters open the next neuron?
They cause channels to open, continuing the action potential from one neuron to the next.
What is an example that uses this process?
When you take drugs that cause hormones to be released like Caffiene.
What chemical helps impulses travel?
Calcium ions
What are the 3 layers of connective tissue that protect the brain and spinal cord called? (blood-brain barrier)
Meninges
Layers of meninges from top to bottom
Skin, Periosteum, Bone, Dura Mater, Arachnoid Membrane, Pia Mater
Dura mater
Thick, tough layer
Arachnoid membrane
Thin, cobweb-like layer
Pia Mater
Thin layer containing lots of blood vessels
What is between the Arachnoid layer and the pia mater?
Cerebrospinal Fluid (CSF)
What does the cerebrospinal fluid do
Protects the brain by preventing it from contacting the skull & maintains the blood brain barrier.
What does the blood brain barrier do?
Controls homeostasis for the brain and prevents infection.
Where is CSF produced
Spaces within the brain called ventricles
What are the four ventricles?
Lateral (Right and Left), 3rd and 4th ventricles.
How are the lateral ventricles connected to the third ventricle?
The thin interventricular (inter= between ventricles) foramen → Foramen of Monro (hole)
What are choroid plexuses
Clusters of capillaries in the ventricles that secrete CSF, causing it to flow around the ventricles, then be absorbed by arachnoid granulations in the blood.
What is CSF constantly doing in the ventricles?
Being produced, circulated, and reabsorbed. (Continuously and closed)
Cerebrum
Largest part of the brain, divided into two hemispheres (right and left)
How are the two hemispheres of the brain connected?
A bundle of nerve fibers called the corpus callosum.
What is the surface of the cerebrum covered with?
Ridges (gyri) and grooves (sulci)
What are the deep grooves that divide portions of the brain?
Fissures
What are the brain’s 3 major layers from superficial to deep?
Cerebral cortex, cerebral medulla, basal nuclei
Cerebral cortex
Gray matter, made of cell bodies and dendrites
Cerebral medulla
White matter, made of myelinated axons.
Basal nuclei
Islands of gray matter
How is the cerebrum divided?
It is divided into 4 lobes based on their functions, and are named for parts of the skull protecting them.
Frontal lobe
Controls voluntary movements like walking, reasoning + decision making. memory, predicting consequences. planning, verbal communication in Broca’s area
How is the frontal lobe separated from the parietal lobe?
The central sulcus
Parietal lobe
Sensations like pain, temperature, and touch, visual spatial processing and body position.
Occipital lobe
Visual processing, vision and memory of objects.
How is the temporal lobe separated from the frontal lobe?
Lateral sulcus
Temporal lobe
Controls memory, comprehension and pronunciation of words. smell and sound, emotional association of memories.
Diencephalon
Small nondescript region within the cerebrum