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1. Types and classification of laryngeal tumours
Benign tumours: Papilloma, polyp, nodule, cyst, hemangioma, chondroma.
Malignant tumours: Mostly squamous cell carcinoma (SCC), rare sarcoma or adenocarcinoma.
Classification by location:
Glottic (true vocal cords).
Supraglottic (epiglottis, false cords, aryepiglottic folds).
Subglottic (below vocal cords).
2. Types and classification of tumours of the nose and paranasal sinuses
Benign: Inverted Papilloma, osteoma, hemangioma, fibroma, angiofibroma.
Malignant: Squamous cell carcinoma (most common), adenocarcinoma, adenoid cystic carcinoma, lymphoma, melanoma, sarcoma.
Classification by site:
Nasal cavity.
Maxillary sinus.
Ethmoidal sinus.
Sphenoidal and frontal sinuses (rare).
3. Types and classification of pharyngeal tumours:
Benign: Papilloma, fibroma, hemangioma, lipoma.
Malignant: Squamous cell carcinoma (most common), lymphoma, adenocarcinoma, sarcoma.
Classification by region:
Nasopharynx (common: carcinoma, lymphoma).
Oropharynx (palatine tonsil, tongue base tumours).
Hypopharynx (pyriform sinus, postcricoid area).
4. Aetiological factors for laryngeal tumour
Smoking (major risk factor).
Alcohol abuse (synergistic with smoking).
Occupational exposures (wood dust, asbestos, paint fumes).
Chronic laryngitis, vocal cord trauma.
HPV infection (esp. papillomas).
5. Early symptoms of laryngeal tumour:
Persistent hoarseness/dysphonia: Most common, especially in glottic cancers.
Foreign body sensation or mild throat discomfort.
Dry cough or slight hemoptysis.
6. Early symptoms of nasal and paranasal sinus tumour
Unilateral nasal obstruction or congestion.
Recurrent epistaxis.
Persistent purulent or blood-stained nasal discharge.
7. Inverted papilloma & treatment
Definition: Benign but locally aggressive tumour of the nasal cavity/paranasal sinuses with high recurrence and potential malignant transformation (into SCC).
Treatment:
Surgical excision is mandatory (endoscopic or open).
Long-term follow-up due to recurrence risk.
8. Please, name the stages of the laryngeal tumour, main division criteria!
Stage I: Tumour limited to one region (glottis/supraglottis/subglottis), vocal cord mobility preserved, no nodes.
Stage II: Involvement of more than one region or impaired vocal cord mobility, no nodes.
Stage III: Local spread with vocal cord fixation or spread outside larynx, or single ipsilateral lymph node <3 cm.
Stage IV: Extensive local invasion and/or multiple/bilateral lymph nodes or distant metastasis.
main criteria = TNM system
T (Tumor): how big the tumor is and how far it spreads locally (T1 = small, T4 = very advanced).
N (Nodes): whether regional lymph nodes are affected (N0 = none, N1–N3 = more/larger nodes).
M (Metastasis): whether the cancer has spread to distant organs (M0 = none, M1 = present).
The TNM combination gives the cancer stage (early vs advanced).
9. Please, name the stages of the paranasal sinus tumour, main division criteria!
Stage I: Limited to sinus mucosa, no bone erosion.
Stage II: Bony invasion but confined to sinus.
Stage III: Extension to adjacent structures (orbit, oral cavity, nasal cavity, ethmoid).
Stage IV: Invasion of cranial base, pterygoid plates, nasopharynx, or distant metastasis.
main criteria = TNM system
T (Tumor): how big the tumor is and how far it spreads locally (T1 = small, T4 = very advanced).
N (Nodes): whether regional lymph nodes are affected (N0 = none, N1–N3 = more/larger nodes).
M (Metastasis): whether the cancer has spread to distant organs (M0 = none, M1 = present).
The TNM combination gives the cancer stage (early vs advanced).
10. Basic principles of surgical treatment of laryngeal tumour
Complete Resection: Remove the entire tumor with clear surgical margins.
Organ Preservation: Prioritize partial removal (partial laryngectomy) to maintain function for early-stage tumors.
Functional Restoration: Post-surgery, rehabilitation is key for speech and swallowing.
Neck Dissection: Remove lymph nodes in the neck if there is a risk of cancer spread.
11. Basic principles of surgical treatment of paranasal sinus tumour
Complete Resection: Aim for the total removal of the tumor with clear margins.
Multidisciplinary Approach: Collaborate with specialists like neurosurgeons and plastic surgeons.
Access and Approach: Choose between minimally invasive (endoscopic) or open surgical techniques based on tumor size and location.
Reconstruction: Use reconstructive surgery to restore function and appearance after tumor removal.