Biology B10: The human nervous system

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1

What do enzymes and cells need in order to work properly?

V stable conditions

  • Can’t work well if conditions around them change too much

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Homeostasis

The regulation of the internal conditions of a cell / organism to maintain optimum conditions for function in response to internal + external changes

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What does homeostasis do?

Maintains optimal conditions for enzyme action + cell functions

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What does homeostasis consist of?

Automatic control systems that ensure internal body conditions stay as constant as possible

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Internal conditions

The conditions inside your body

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In the human body, what internal conditions does homeostasis control?

  1. Body temperature

  2. The water content of the body

  3. Blood glucose concentration

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What do automatic control systems in humans involve?

  • Nervous responses in nervous system

  • Chemical responses in hormone system

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What do all automatic control systems need to function?

  1. Receptor cells

  2. Coordination centres

  3. Effectors

<ol><li><p>Receptor cells</p></li><li><p>Coordination centres</p></li><li><p>Effectors</p></li></ol>
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Receptors cells

Detect changes in the environment (stimuli)

  • Pass info to coordination centre

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Environment

Refers to the bodies

  • Internal conditions (eg blood glucose concentration)

  • External conditions (eg temp of skin)

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Stimulus

A change to the environment

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Coordination centres

Receives + processes info from receptor cells

  • Sends instructions to the effector

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Examples of coordination centres

  • Brain

  • Spinal cord

  • Pancreas

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Effectors

  • Muscles or glands

  • Bring about responses to stimulus that restore body conditions to optimum levels

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What does the human nervous system consist of?

  • Central nervous system (CNS)

  • Peripheral nervous system (PNS)

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What makes up the central nervous system (CNS)?

  • The brain

  • Spinal cord

<ul><li><p>The brain</p></li><li><p>Spinal cord</p></li></ul>
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What makes up the peripheral nervous system (PNS)?

All of the nerves in the body

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Role of nervous system

Enables humans to react to surroundings + coordinate behaviour

  • Done thru reflec arc

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Neurones

Nerve cells

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How is information sent through the nervous system as?

Electrical impulses

  • Electrical signals that pass along neurones

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Nerves

A bundle of neurones

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How does our nervous system work?

  1. Receptors detect stimulus

  2. Sends EI down neurones to the CNS

  3. CNS = coordination centre

  4. CNS sends EI down the motor neurones to effectors

  5. Effectors bring about a response

    • Eg muscles contract or glands secrete hormones

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Sensory neurones

Nerve cells that carry impulses from sense organs to CNS

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Motor neurones

Carry impulses from the CNS to the rest of the body

  • To make effectors respond

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How do effectors like muscles and glands respond to the arrival of impulses?

  • Muscles: contracts

  • Glands: secretes hormones

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What makes reflexes automatic and rapid?

No decision making by conscious part of the brain

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Since reflexes are automatic and rapid how does it help us?

Protect us from danger

  • So minimise damage to the body

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Why are reflexes important?

  • Protect us from danger

  • They take care of basic body functions

    • Eg breathing

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What types of neurones do reflexes involve?

  • Sensory neurones

  • Motor neurones

  • Relay neurones

<ul><li><p>Sensory neurones</p></li><li><p>Motor neurones</p></li><li><p>Relay neurones</p></li></ul>
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Nerve cell labelled

  • Axon = Long, EI travel along

  • Axon surrounded by myelin sheath (fatty cells)

    • Insulates EI

  • Dendrites = branched endings, connect neurons tog

<ul><li><p>Axon =  Long, EI travel along</p></li><li><p>Axon surrounded by myelin sheath (fatty cells)</p><ul><li><p>Insulates EI</p></li></ul></li><li><p>Dendrites = branched endings, connect  neurons tog</p></li></ul>
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Relay neurones

Connect a sensory + motor neurone

  • In CNS

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Reflex pathway

  1. Stimulus

  2. Receptor

  3. Sensory neurone

  4. Relay neurone

  5. Motor neurone

  6. Effector

  7. Response

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Synapses

Junction, gap where the ends of two neurons meet

  • Ensures EI travel only in 1 direction

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In the reflex arc, where are synapses found?

Between

  • Sensory + relay neurones

  • Relay + motor neurones

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How do synapses work?

  1. EI arrives at the end of the axon on the neuron

  2. Chemicals released from vesicles

  3. Diffuse across synaptic gap

  4. Chemicals attatch to surface of next neurone + set up new EI

<ol><li><p>EI arrives at the end of the axon on the neuron</p></li><li><p>Chemicals released from vesicles</p></li><li><p>Diffuse across synaptic gap</p></li><li><p>Chemicals attatch to surface of next neurone + set up new EI</p></li></ol>
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<p>Which is the only place in the nervous system where drugs can affect the nervous system and why?</p>

Which is the only place in the nervous system where drugs can affect the nervous system and why?

Synapses

  • Only part of the NS where messages are chemical, not electrical

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How do neurotransmitter chemicals cross the synapse?

Diffusion

  • Down a CG

  • Passive process

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How can drugs trigger impulses in different regions of the brain?

When they bind to neurotransmitter receptors

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What can the frequent use of drugs lead to?

Overstimulation of neurons → loss of function

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Brain

  • Controls complex behaviours eg language

  • Made up of interconnected neurons

  • Organ part of the CNS

<ul><li><p>Controls complex behaviours eg language</p></li><li><p>Made up of interconnected neurons</p></li><li><p>Organ part of the CNS</p></li></ul>
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Cerebral cortex

  • Highly folded, outer layer of the brain

  • Controls consciousness, memory + language

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Cerebellum

Controls balance + coordinates movements

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Medulla

  • Controls unconscious activities

    • Heart + breathing rate

<ul><li><p>Controls unconscious activities</p><ul><li><p>Heart + breathing rate</p></li></ul></li></ul>
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Hypothalamus

Controls body temperature

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Pituitary gland

Produces different hormones

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Why is the understanding of the brain limited?

  • V complex

  • Diff regions can’t be studied in isolation

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Why is studying the brain difficult + difficult to treat brain damage/diseases?

  • Protected by skull → tricky to access

  • Structures in brain are v complex

    • So difficult to work out which parts of the brain carry out specific functions

  • Delicate + easy to damage

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Why can brain surgery be performed on conscious patients?

No sensory nerve endings in the brain

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Benefits of procedures carried out on the brain and nervous system

Improving quality of someone’s life

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Risks of procedures carried out on the brain and nervous system

  • More permanent damage

    • As we don’t fully understand how brain + NS work

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Eye

  • Sense organ

  • Contains receptors sensitive to light intensity + colour of light

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Cornea

  • Transparent lens

  • It refracts light rays as it enters the eye and focuses it onto the retina

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Iris

Colored part of the eye

  • Controls size of the pupil (+ so how much light reaches the retina)

  • Made of muscles that contract or relax to change the size

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Lens

  • Transparent lens

  • Starts focusing of light rays onto the retina

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What can the lens do?

Change shape, allowing us the focus on distant or near objects

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Retina

  • Back of the eye

  • Contains receptor cells for light

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What do the receptor cells in the retina allow us to detect?

  • Light intensity

  • Light colour

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Purpose of the eye?

To receive light + focus it onto the retina at the back of the eye

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How does the eye detect light?

  1. Light rays pass thru the cornea → pupil in the centre of the iris → lens

  2. Lens focuses LR onto the retina (back of eye)

  3. Receptor cells in retina send the EI down the optic nerve to the brain

  4. When brain receives these messages + interprets them as a visual image

<ol><li><p>Light rays pass thru the cornea → pupil in the centre of the iris → lens</p></li><li><p>Lens focuses LR onto the retina (back of eye)</p></li><li><p>Receptor cells in retina send the EI down the optic nerve to the brain</p></li><li><p>When brain receives these messages + interprets them as a visual image</p></li></ol>
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Sclera

  • White part of the eye

  • Tough outer structure that protects the eye

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Optic nerve

Sensory neurone that carries impulses betw the eye + the brain

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How do the ciliary muscles and suspensory ligaments work with the lens?

Allow us to focus on distant or near objects

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Pupil

The space in the centre of the iris which light passes through

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What two groups of muscle is the pupil reflex controlled by?

  • Radial muscle

  • Circular muscles

<ul><li><p>Radial muscle</p></li><li><p>Circular muscles</p></li></ul>
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Blind spot

Point at which the optic nerve leaves the eye that has no retina

  • But the brain fills in the gap

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How does focusing light differ in the cornea and the lens?

  • Cornea: fixed focus

  • Lens: allows us to focus on near and distant objects (shape of lens can change)

<ul><li><p>Cornea: fixed focus</p></li><li><p>Lens: allows us to focus on near and distant objects (shape of lens can change)</p></li></ul>
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Accomodation

The ability to change the shape of the lens to focus on near or distant objects

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How does light from distant and near objects need to be focused and why?

  • Distant: small amount

    • Light from distant objects travels in almost parallel rays

  • Near: a large amount

    • Light from near objects spreads out v strongly

<ul><li><p>Distant: small amount</p><ul><li><p>Light from distant objects travels in almost parallel rays</p></li></ul></li><li><p>Near: a large amount</p><ul><li><p>Light from near objects spreads out v strongly</p></li></ul></li></ul>
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How do we focus on distant objects?

  1. Ciliary muscle relaxes

  2. So suspensory ligaments pulled tight

  3. Lens pulled thin

  4. So LR only slightly refracted

    • LR will be focused on a point on the retina

<ol><li><p>Ciliary muscle relaxes</p></li><li><p>So suspensory ligaments pulled tight</p></li><li><p>Lens pulled thin</p></li><li><p>So LR only slightly refracted</p><ul><li><p>LR will be focused on a point on the retina</p></li></ul></li></ol>
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How do we focus on near objects?

  1. Ciliary muscle contracts

  2. So the suspensory ligaments loosen

  3. Lens is thicker

  4. It refracts the LR more strongly

    • The LR will be focused on a point in the retina

<ol><li><p>Ciliary muscle contracts</p></li><li><p>So the suspensory ligaments loosen</p></li><li><p>Lens is thicker</p></li><li><p>It refracts the LR more strongly</p><ul><li><p>The LR will be focused on a point in the retina</p></li></ul></li></ol>
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Hyperopia

Long-sightedness

  • Can focus on distant objects

  • Can’t focus on nearby objects

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Myopia

Short-sightedness

  • Can focus on near objects

  • Can’t focus on distant objects

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How is an image formed?

Upside down

  • But the brain interprets it the right way up

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General causes of eye defects

Light rays don’t focus correctly on the retina

  • So they are short or long-sighted

  • Image on retina = out of focus

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What is the brain made of?

Billions of interconnected neurones

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What does the brain have?

Diff regions that carry out diff functions

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