Protic and Polar Aprotic Solvents

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11 Terms

1
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Water

Protic

2
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Methanol

Protic

3
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Ethanol

Protic

4
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Ammonia (NH3)

Protic

5
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Acetic Acid (CH3COOH)

Protic

6
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Acetone (CH3COCH3)

Polar Aprotic

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<p>Dimethylformamide (DMF) </p>

Dimethylformamide (DMF)

Polar Aprotic

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<p>Hexamethylphosphoramide (HMPA) </p>

Hexamethylphosphoramide (HMPA)

Polar Aprotic

9
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<p>Dimethylsulfoxide (DMSO) </p>

Dimethylsulfoxide (DMSO)

Polar Aprotic

10
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<p>Acetonitrile</p>

Acetonitrile

Polar Aprotic

11
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Which solvent type is ideal for SN2 reactions?

polar aprotic - these solvents lack hydrogen bonding abilities, and therefore do not interact with the nucleophile, leaving it free for the backside attack.