912 CHOLESTEROL DRUGS

What trugs help oxidative breakdown?

Clofirbic acid

Clofibrate

MOA of statins:

HMG-CoA inhbitiors

Alicrocumab:

PCSK9 inhibitor: revents the degradation of LDL receptors marked by PCSK9 for destruction/recycling

Anacetrapib:

CETP Inhibitor

What drug is this

Anaceptrapib

Atorvastatin MOA

Competitive HMG-CoA reductase inhibitor

What drug is this

Atorvastatin

MOA of cholestyramine (questran)

Absorbs and eliminates bile acids, treiggering the liver to take up cholesterol (LDL) from the blood

What drug is this

Cholestyramine (questran)

Clofibrate (Atromid-S) MOA

Stimulation of peroxisomes; increases LPL activity, thereby lowering chylomicrons and VLDL; also increases HDL

What drug is this

Clofibrate (atromid-S)

Evolovumab (repatha) MOA

PCSK9 ibhibitor. Prevents the degradation of LDL receptors marked by PCSK9 for destruction/recyling

Ezetimibe (Zetia) MOA

inhibits the uptake of dietary cholesterol from the small intestines; often co-applied with statins. Binds to Nieman-Pick C1 like protein of the gastrointestinal tract epithelial cells,. blocks aminpeptidase N and interrupts a carveloin-1-annexin A2 complex involved with trafficking cholesterol

What drug is this

Ezetimibe

b-lactam ring, synthetic

Fenofibrate (Tricor) moa

Activation of PPARalpha (Peroxisome proliferator-activated receptor alpha, also called NR1C1; stimulation of protein synthesis in peroxisomes, increases thereby peroxisomal activities important for lipid degradation

what drug is this

fenofibrate (tricore)

Fluvastatin (Lescol) MOA

competitive HMG-CoA reductase inhibitor

what is this drug

fluvastatin (lescol)

MOA of Inclisiran (Leqvio)

PCSK9 inhibitor. Prevents the degradation of LDL receptors marked by PCSK9 for destruction/recycling though inhibitor of the translocation of the protein PCSK9

Lovastatin (Mevacor) MOA:

T1/2-1-3hr; competitive HMG-CoA reductase inhibitor

What drug is this

Lovastain (mevacor)

Pravastatin (pracachol) MOA

Competivie HMG-CoA reductase inhibitor

what drug is this

Pravastatin (pracachol)

Rosuvastatin (crestor) moa

competitive HMG-CoA reductase inhbitor: modestly elevates HDL

what drug is this

rosuvastatin (crestor)

SImvastatin (Zocor) moa

T1/2-1-3hr competitive hmg-coa reductase inhbitor

what drugis this

simvastatin (zocor)