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Lymphatic System
Composed of a network of vessels, ducts, nodes, and organs. Provides defense against infection.
Secondary Circulatory System
The enlarged regions of the lymphatic vessels are known as
Referring to the lymphatic system
lymph nodes
Lymph nodes contain B and T cells true or false?
True
Lymphocytes
Are a type of white blood cell that contain B and T fighter cells.
What are the two major groups of leukocytes?
granulocytes and agranulocytes
leukocytes
White blood cells involved in immune response.
Agranulocytes include what kind of white blood cells?
lymphocytes and monocytes
Granulocytes include which kinds of white blood cells?
Neutrophils, Eosinophils, Basophils
Lymphatic cells transport excess fluid away from the interstitial spaces in most tissues and return it to the bloodstream. True or false
True
Why does the lymphatic system need to transport excess fluid away from the interstitial spaces?
so the fluid will not accumulate in the tissue spaces
Lymphatic capillaries are
microscopic closed ended tubes that extend into the interstitial spaces forming complex networks that are parallel to the blood capillaries throughout the body.
How many layers are lymphatic vessels composed of?
3 Layers
Where do the larger lymphatic vessels lead?
to specialized organs called lymph nodes, after this these vessels merge into lager lymphatic trunks.
Lymphatic Trunks function:
to drain lymph from the lymphatic vessels is the function of what in the lymphatic system?
Locations of the lymph nodes:
-Cervical region
-Axillary region
-Supratrochlear region
- Inguinal region
-Pelvic cavity
-Abdominal cavity
-Thoracic cavity
What are thymocytes?
immature T cells
T cells leave the thymus and provide_____. Epithelial cells in the ______ secrete hormones called ______ which stimulate ration of T lymphocytes.
1. immunity
2. thymus
3. thymosins
thymosins stimulate
ration of T lymphocytes
What is the largest lymphatic organ?
the spleen
pathogens
disease causing agents
adaptive defense
a specific response by the immune system to a given pathogen
What are examples of mechanical barriers?
Passageways in the respiratory, digestive, urinary, and reproductive systems create ________ barriers.
A reaction that provides localized redness and swelling, heat, and pain is called?
Inflammation
Examples of chemical barriers are what?
Gastric juice, tears,
Enzymes in the body provide _______ barrier to pathogens.
chemical
Defesins
are small proteins that are antibiotic/antimicrobial; found in the mucous of the Nasal conchae
collections
are proteins that provide broad protection against bacteria, yeasts, and some viruses.
Complements
is a group or proteins that are located
Secondary Immune Response
Immune response after the body has already been exposed to a specific antigen. Response is faster, of greater magnitude, and more prolonged.
Primary Immune Response
Immune response the first time the body is exposed to a particular antigen. Does not peak until 10-17 days after exposure.
naturally acquired active immunity
exposure to live pathogens resulting in stimulation of an immune response with symptoms of a disease.
artificially acquired active immunity
this is through the mechanism of exposure with a vaccine that contains weakened or dead pathogens or their components resulting in stimulation of an immune response without symptoms of a disease.
naturally acquired passive immunity
antibodies passed to fetus from pregnant woman with active immunity or to a newborn through breast milk or colostrum from a woman with active immunity
artificially acquired passive immunity
injection of an antiserum containing specific antitoxins to result in short-term immunity without stimulating an immune response.
Type IV(Delayed reaction)
T cells and macrophages release chemical facts into the skin, an example of this is dermatitis, Mantoux for TB.
Type 3( immune complex reaction)
Phagocytosis and lysis cannot clear antigen-antibody complexes; and example of this is autoimmunity
Tissue rejection reaction
immune system produces antibodies against transplanted tissue
Isograft
is a transplant which comes from an identical twin; example of this is a bone marrow transplant from a healthy twin to an unhealthy twin who has leukemia
allograft
is a same species transplant
kidney transplant is from a relative or closely matched Donner
Xenograft
is a different species transplants, an example is heart valves or parts of a kidney from a pig
autoimmunity
reaction of immune response to one's own tissues
autoantibodies
Antibodies produced against self-antigens
antigen presenting cells
dendritic cells, macrophages, B cells
MHC 2
found on certain immune cells, used to present foreign antigens to WBC
takes in the bacteria
proliferates
something that grows, advances, or multiplies rapidly
Helper T cell releases
IL-2
cytokines
Chemicals released by the immune system communicate with the brain.
Hypersensitivity reactions
Excessive response to primary or secondary effect of drug
Type 1 hypersensitivity
is commonly called and allergy and the antigens that trigger allergic responses are called allergens.
tissue rejection reaction
immune system produces antibodies against transplanted tissue
autoantibodies
the immune system can fail to distinguish self from non self, producing antibodies
Haptens
antigens too small to provoke immune responses; attach to carrier molecules
allergic reactions result from
mast cells burning and releasing allergy mediators such as histamine, chemicals cause allergy symptoms such as hives, hay fever, skin irritations(atopic dermatitis). These reactions can sometimes cause decreased BP or difficulty in breathing.
innate immunity is
the type of immunity that you are born with it protects you against pathogens, and gives you a general defense.
Adaptive Immunity is
the type of immunity that gives you specific defenses, builds antigens, and protects the body against pathogens.
innate immunity examples
chemical barriers, increasing phagocytes, collecting(proteins that are protective), complement( group of proteins inside plasma, natural killer cells, phagocytosis, fever, and interleukins.
species resistance
natural ability of one type of organism to resist infection by pathogens that cause disease in another type of organism
1st line of defense
mechanical barriers
2nd line of defense
all or nonspecific defenses
third line of defense
is resistance to specific types of pathogens due to their toxins or metabolic by products.
inflammation
a tissues response to injury that helps prevent the spread of infectious agents into nearby tissues.
phagocytosis
"cell eating" engulfing large particles
fever
elevated body temperature
Natural killer cells are a small population of lymphocytes that provide adaptive defense mechanisms. NK cells provide defense against viruses and cancer cells by perforating the cell (perforins).
true
Roles of lymphatic capillaries
-Absorption of dietary fats
-Return small proteins with help of osmotic pressure
-collect and deliver excess fluid(prevents edema)
- Deliver foreign particles (bacteria)
hydrostatic pressure
the pressure within a blood vessel that tends to push water out of the vessel
Monocytes and macrophages constitute the mononuclear phagocytic system true or false.
true
Collectins are apart of innate defense and they are proteins that provide broad protection faints bacteria, yeasts and some viruses. They also detect sugar molecules.
true
lymphocytes and fibroblasts produce interferons which are proteins that are produced to respond to tumor cells or viruses. true or false.
true
defensins are produced by neutrophils and other types of granular white blood cells, defensins are peptides. true or false
true