Part 24: Tissue Tolerances

TD 5/5 aka

1. traditional “tolerance dose”

2. minimal tolerance dose

TD 5/5 stands for

tolerance dose: 5% of patients having adverse rxns within 5 years of tx

TD 50/5 aka

1. TD 5/50

2. maximal tolerance dose

TD 50/5 stand for

50% of patients having adverse rxn within 5 years

TD/ 95% Probability

the tumor dose

In theory, the dose at which you have 95% probability of local control

(key: local control, we are confident the tumor wont recur locally BUT the cancer might have already spread somewhere else)

Mnemonic for all partial tolerances

6 OPs @ 6 HEBS found Stinky, Stenchy, Stanky (5000) buying Cola (5500) Loka (4500)

6000

Oral Cavity

Pharynx

Heart

Esophagus

Brain

stomach

5000 (long stuff)

Spinal cord

Small intestines

salivary glands

Cola= Colon 5500

Loka = Lung 4500

Whole Larynx

7000

whole bladder

Bladder bs = 6500

mnemonic for whole 6000

Ass= Rectum

Eaters= TM Joint Mandible

Make = Mature bone & cartilage

Money = Muscle

Fast = Adrenal

Whole skin

5kin5

5500

femoral head i and 2 whole

femoral = feamour = 5200

Whole 5000 mnemonic

for breasts my vision is 5/5

optic Never and chiasma

5 things are 45S (whole)

hey Big Brain, don’t stick TP up your colon. That’s an x-ray that has been burt into my retinass

1. Brain

2. Thyroid

3. Pituitary

4. Colon

5. Retina I & II

parotid whole

paro3ed and 2 of them

3200

liver (whole)

bender 3000

kidney (whole)

23 and kindey

2300

Growing cartilage and bone (whole) (child)

1000

Eye Lens I and II (whole)

1000

Bone Marrow whole

250

Bone (sex) balls 25

Ovary whole

200-600

2 of them boo

Fetus whole

feTWOs

200

Testes whole

100

Whole heart

4000

4 chambers

esophagus (whole)

e5ophagu5

5500

Stomach (whole)

5tomach

5000

Spinal Cord (whole)

u cant a4rd to 7ever it

4700

small intestine whole

4000

lung whole

1700 america 50s smoke

1750

Trye or False: A whole organ can tolerate a higher dose than a part of an organ

False, other way around