Module 4 Weekly Quizzes

Which of the following tissues represents a continuously dividing population?
a. Cardiac myocytes
b. Neurones
c. Hepatocytes
d. Gut epithelium
e. Renal tubule cells

d. Gut epithelium

Which of the following responses to cell injury represents a reversible change?
a. Apoptosis
b. Fatty change
c. Autolysis
d. Dry gangrene
e. Coagulative necrosis

b. Fatty change

Canine parvovirus initially infects which of the following tissues?
a. small intestine
b. large intestine
c. lymphoid tissue
d. heart
e. liver

c. lymphoid tissue

Which of the following dietary components are important in protecting against oxidative stress? (ie. act as antioxidants)
a. carbohydrate
b. Vitamin E
c. Vitamin K
d. protein
e. Iron

b. Vitamin E

Which of the following characteristics generally applies to products of Phase I metabolic reactions?
a. They are less lipid soluble than the parent compound
b. They are less chemically reactive than the parent compound
c. They are less rapidly excreted than the parent compound
d. They are less toxic than the parent compound
e. They are less ionized than the parent compound

a. They are less lipid soluble than the parent compound

If the half-life is the loss of 50% of a drug from the body, how many half-lives would reduce plasma concentration of a drug to less than 1% of the original value?
a. 3
b. 5
c. 7
d. 9
e. 11

c. 7

The volume of distribution of a drug is 0.1 L/Kg in canines. The effective plasma concentration is in the range 1-2 microgram/ml. What can you deduce about the distribution of this drug around the body following administration?

The volume of distribution is low and indicates that the drug is largely confined to the plasma/vascular space

Give one reason why a drug may have a low volume of distribution

High degree of plasma protein binding or large molecule unable to leave the vascular space

Which one of the following is the most important intermediate host of Echinococcus granulosus in the UK?
a. red foxes
b. sheep
c. dogs
d. cows
e. pigs

b. sheep

Which type of the following breeds of cattle would be considered to be a "British hill cattle" or "celtic" type?
a. Hereford
b. Saler
c. Shorthorn
d. Limousin
e. Galloway

e. Galloway

Which of the following European production systems is likely to produce animals in finished condition for slaughter by 12 months of age?
a. Cereal (bull) beef
b. Forage based finishing
c. Grass silage beef
d. Maize silage beef
e. Mixed grass and concentrate

a. Cereal (bull) beef

Which of the following is the most popular breed of beef cattle in the UK?
a. Limousin
b. Shorthorn
c. Galloway
d. Hereford
e. Saler

a. Limousin

Inhibited larval development (hypobiosis) in Ostertagia ostertagi:
A. occurs in response to exposure of L4s to cold climatic conditions
B. occurs when L3s arrest development in abomasal glands
C. occurs only in adult cattle
D. occurs when L4s arrest development in abomasal glands
E. occurs when L3s arrest development in muscle tissue

D. occurs when L4s arrest development in abomasal glands

Peptidoglycan in bacteria is made up of which one of the following?
a. Poly D Glutamic acid
b. Lipid A
c. N acetyl glucosamine/N acetyl muramic acid
d. Mannon
e. Chitin

c. N acetyl glucosamine/N acetyl muramic acid

Which one of the following is not part of the innate immune system?
a. Dendritic cells
b. Acute Phase Proteins
c. Phagocytes
d. CD8+ T cells
e. Complement

d. CD8+ T cells

Which of the following is NOT a means by which intracellular pathogens survive within macrophages?
a. Survive within the phagolysosome
b. Inhibit fusion of phagasomes and lysosomes
c. Escape from the phagosome
d. Prevent formation of a phagosome
e. Inhibit acidification of the phagosome

d. Prevent formation of a phagosome

Taenia saginata cysts are found in the muscles of:
a. dogs
b. horses
c. sheep
d. humans
e. cattle

e. cattle

What is the normal stimulus for larval arrest in Toxocara canis infection?
a. drug treatment
b. pregnancy
c. the external temperature
d. anthelmentic resistance
e. the host immune response

e. the host immune response

The adults of which fluke, can be found in the mammalian blood stream?
a. Fasciola
b. Schistosoma
c. Fascioloides
d. Paramphistomum
e. Dicrocoelium

b. Schistosoma

Genes encoding for which of the following elements are most likely to be part of the core bacterial genome?
a. DNA replication
b. Antibiotic resistance
c. Fimbriae
d. Bacteriophage
e. Restriction/modification systems

a. DNA replication

Specialized transduction involves which one of the following?
a. Type IV secretion system
b. Uptake of naked DNA
c. Lysogenic bacteriophage
d. Transposons
e. Sex pilus

c. Lysogenic bacteriophage

Which of the following sterilizes by dry heat?
a. Hot air oven
b. Boiling
c. Ethylene oxide
d. Autoclave
e. Irradiation

a. Hot air oven

What is the commonest cause of foodborne illness in the UK?
a. Escherichia coli O157
b. Mycobacterium bovis
c. Campylobacter species
d. hepatitis A virus
e. Salmonella species

c. Campylobacter species

What is the primary cellular mechanism of action of the phenothiazine antiemetic drugs?
a. Dopamine, D2 receptor agonists
b. Dopamine, D2 receptor antagonists
c. Neurokinin, NK1 receptor antagonists
d. Neurokinin, NK1 receptor agonists
e. Serotonin, 5HT3 receptor antagonists

b. Dopamine, D2 receptor antagonists

Following entry of a virus particle into a cell and release of the viral genome, which of the following events would be first to occur?
a. lysis of the cell
b. expression of the viral genome
c. maturation of virions
d. assembly of new virus particles
e. replication of the viral genome

b. expression of the viral genome

Which of the following is not commonly a type of veterinary viral genome?
a. double stranded DNA
b. hybrid RNA and DNA
c. segmented RNA
d. double stranded RNA
e. single stranded RNA

b. hybrid RNA and DNA

Why are Macrocyclic lactone anthelmintic drugs ineffective against fluke and tapeworm?
A. fluke and tapeworm actively pump the macrocyclic lactones out of their cells
B. the macrocyclic lactones are insufficiently soluble to reach the site of the helminth within the host
C. the macrocyclic lactones cannot penetrate into the fluke and tapeworm
D. the fluke and tapeworm cannot metabolize the macrocyclic lactones to their active form
E. fluke and tapeworm do not possess the target receptor

E. fluke and tapeworm do not posses the target receptor