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neurons
individual cells in the nervous system that receive, integrate and transmit information
soma (cell body)
contains the cell nucleus and much of the chemical machinery common to most cells
dendrites
parts of the neuron that are specialized to receive information
myelin sheath
insulating material that encases some axons
speeds up the transmission of signals that move along axons
condition in which the myelin sheath degenerates
multiple sclerosis
axon
long thin fiber that transmits signals away from the soma to other neurons or to muscle glands
axon terminal / terminal button
small knob that secretes chemicals known as neurotransmitters
synapse
a junction where information is transmitted to one neuron to another
neurotransmitter
chemicals which serve as messengers that may activate nearby neurons
glia
cells found throughout the nervous system that provides various types of support for neurons
synaptic cleft
microscopic gap between the terminal button of one neuron and the cell membrane of another neuron
information flow in neurons
dendrites → cell body → axon
resting potential of a neuron
its stable, negative charge when the cell is inactive
the action potential
a very brief shift in a neuron’s electrical charge that travels along an axon
absolutely refractory period
minimum length of time after an action potential, during which another action potential cannot begin, usually 1-2 milliseconds
all-or-none law
either a neuron fires or doesn't, stating that the strength of a neuron’s response doesn't depend on the strength of the stimulus
postsynaptic potentials
a voltage change at a receptor site on a postsynaptic cell membrane
expiatory post synaptic membrane
positive voltage change
increased likelihood that the postsynaptic neuron will fire action potentials
inhibitory postsynaptic potential
negative voltage change
decreased likelihood that the postsynaptic neuron will fire action potentials
reuptake of neurotransmitters
a process in which neurotransmitters are sponged up from the synaptic cleft by the presynaptic membrane
acetylcholine (ACh)
is found throughout the nervous system, and is the only neurotransmitter between motor neurons and voluntary muscles
released by motor neurons controlling skeletal muscles
contribute to attention, arousal, and memory (inadequate supply can lead to alzheimer's)
Dopamine (DA)
contributes to control of voluntary movement
DA circuits known as “reward pathways”
degeneration → Parkinson’s disease
overactivity → schizophrenia
Norepinephrine (NE)
Contributes to mood regulation and arousal
disorders associated with dysregulation → depression
Serotonin
involved in regulation of sleep and wakefulness, eating, aggression
dysregulation → depressive disorders, OCD, eating disorders
GABA (gamma-aminobutyric acid)
seems to produce only inhibitory postsynaptic potentials
dysregulation → anxiety disorders
endorphins
internally produced chemicals that resemble opiated in structure and effects
PNS
made up of nerves that lie outside the brain and spinal cord
nerves
bundles of neuron fibers (axons) that are routed together in the PNS
Afferent nerve fibers
axons that carry information inward to the CNS, from the periphery of the body
Efferent nerve fibers
axons that carry information outward of the CNS towards the periphery of the body
Somatic nervous system
made up of nerves that connect to voluntary skeletal muscles and to sensory receptors
Autonomic Nervous system
nerves that connect to the heart, blood vessels, smooth muscles, and glands
Sympathetic division in ANS
mobilizes the body’s resources for emergencies
Parasympathetic division in ANS
generally conserves bodily resources, to save and store energy
CNS
consists of the brain and spinal cord
CNS bathed in what, for what
Cerebrospinal fluid (CBF), which nourishes and cushions the brain
Spinal cord function
carry the brain’s commands to peripheral nerves, and relay sensations from the periphery body to the brain
Lesioning
destroying a piece of the brain
Electrical stimulation of the brain (ESB)
sending a WEAK current into a brain structure to stimulate it
CT (computerized tomography) scan
X-ray of the brain structure, horizontal slice of the brain
MRI (magnetic resonance imaging)
map out a 3d, high resolution images of the brain structure
PET (positron emission tomography)
to map chemical activity in the brain over time
Functional magnetic resonance imaging (fMRI)
monitor blood flow and oxygen consumption in the brain to identify areas of high activity
Parts of the hindbrain
medulla
pons
cerbellum
Medulla
controls largely unconscious but essential functions such as breathing, maintaining muscle tone and regulating circulation
Pons
includes a bridge of fibers that connects the brainstem with the cerebellum, also contains several clusters of cell bodies involved with sleep and arousal
Cerebellum
relatively large and deeply folded structure adjacent the the back surface of the brainstem
involved in the coordination of movement and is critical to the sense of equilibrium/ physical balance, key role in sensing the position of our limbs
brain circuits running from the cerebellum to the prefrontal cortex seem to be involved in high-order functions, like attention, planning and visual perception
The midbrain
integrates sensory processes
releases dopamine involve in the performance of voluntary movements
reticular formation contributes to he modulation of muscle reflexes, breathing and pain perception, as well as regulation of sleep and arousal
the forebrain
the largest and most complex region of the brain, consisting of the thalamus, hypothalamus, limbic system and cerebrum
the thalamus
a structure in the forebrain through which all sensory information (except smell) must pass to get to the cerebral cortex
hypothalamus
a structure found near the base of the forebrain that is involved in the regulation of basic biological needs
fighting, fleeing, feeding, mating
limbic system
hippocampus and adjacent structures play a role in in consolidation of memories for factual information
amygdala: centre role in the learning of fear response and other basic emotional responses
cerebrum
cerebral cortex: convoluted outer layer of the cerebrum
cerebral hemispheres: the right and left halves of the cerebrum
corpus callous
major structure that connects the 2 hemispheres
frontal lobe function
primary motor cortex, controls the movement of muscles
more of the cortex is dedicated to muscles we have find control over (lips fingers, tongue)
prefrontal cortex — executive control system
temporal lobe
primary auditory cortex, devoted to auditory processing
occipital lobe
includes the cortical area where most VISUAL signals are sent and visual processing is begun
parietal lobe
primary somatosensory cortex, area that registers sense of touch; integrate visual input
Broca’s area
production of speech
Wernick’s area
comprehension of language
Neurogenesis
formation of new neurons
stress → surprise the rate of neurogenesis
physical exercise → enhances the rate of neurogenesis
What processing does the right and left brain do?
Spatial musical, visual — R
Verbal — L
chromosomes
threadlike strands of DNA molecules that carry genetic information
Genes
DNA segments that serve as key functional units in hereditary transmission
polygenic traits
characteristics that are influenced by more than one pair of genes
family studies
researchers assess hereditary influence by examining blood relatives to see how much hey resemble one another on a specific trait
twin studies
researchers assess heredity influence by comparing the resemblance of identical and fraternal twins with respect to a trait
adoption studies
assess hereditary influence by examining the resemblance between adopted children and both they biological and their adoptive parent
natural selection
principle stating that heritable characteristics that prove a survival or reproductive advantage are more more Riley than alternative characteristics to be passed on to subsequent generations, and thus they come to be selected over time
adaptation
an inherited characteristic that increases in a population through natural selection, bc it helped solve a problem of survival or reproduction during the time it emerged