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Function of the Brain
The brain converts internal and external stimuli into electrochemical impulses.
Neurons
Process and transmit information.
Glial Cells (Glia)
Support, insulate, nourish, and clean up; also contribute to neural communication.
Dendrites
Receive signals; "tree-like" branches covered in receptors.
Soma (Cell Body)
Contains nucleus & organelles; integrates incoming signals.
Axon Hillock
Junction where action potential begins.
Axon
Long fiber that transmits the electrical impulse.
Myelin Sheath
Fatty insulation (made by glia) that speeds transmission.
Nodes of Ranvier
Gaps in myelin where signal regenerates.
Terminal Buttons
Release neurotransmitters into the synapse.
Signal Direction
Dendrites → Soma → Axon → Terminal → Synapse → Next Neuron
Sensory (Afferent) Neurons
Receive environmental input (e.g., light, sound, touch).
Motor (Efferent) Neurons
Output to muscles and glands.
Interneurons
Short, local connectors within brain regions or spinal cord.
Astrocytes
Star-shaped; regulate blood flow, synchronize firing of groups of neurons, form part of the blood-brain barrier.
Oligodendrocytes
Create myelin in the CNS; one cell can myelinate multiple axons.
Schwann Cells
Create myelin in the PNS; one cell = one axon segment.
Microglia
Act as immune cells; clean debris, dead neurons, and fight infections.
Radial Glia
Guide neuron migration during fetal development.
Blood-Brain Barrier (BBB)
Protects brain from toxins and infections.
Resting Potential
-70 mV (inside negative relative to outside).
Action Potential
Triggered when threshold (~-55 mV) is reached at axon hillock.
Sodium (Na⁺) Ions
Rush in during depolarization.
Potassium (K⁺) Ions
Exit during repolarization.
Na⁺/K⁺ Pump
Restores resting potential.
Saltatory Conduction
Speeds conduction by the impulse "jumps" between Nodes of Ranvier.
Reuptake
NTs reabsorbed by presynaptic neuron (e.g., serotonin).
Enzymatic Breakdown
NTs degraded by enzymes (e.g., acetylcholinesterase).
Autoreceptors
On presynaptic cell; detect released NTs → inhibit further release.
Negative Feedback
Postsynaptic neuron sends chemical message backward → stop release.
Amino acids
Glutamate (excitatory), GABA (inhibitory).
Monoamines
Dopamine, serotonin, norepinephrine.
Acetylcholine (ACh)
Muscle movement, memory.
Neuropeptides
Endorphins, substance P (modulate mood/pain).
Hindbrain
Medulla, pons, cerebellum; vital functions (breathing, heartbeat), movement coordination.
Midbrain
Tectum, tegmentum; visual & auditory reflexes, movement.
Forebrain
Thalamus, hypothalamus, limbic system, basal ganglia, cortex; sensory processing, emotion, motivation, cognition.
Ventricular System
Four cavities filled with cerebrospinal fluid (CSF).
Hydrocephalus
Blockage → ventricles enlarge and pressure increases.
Frontal Lobe
Motor output, speech (Broca's area), planning, reasoning, personality.
Parietal Lobe
Somatosensory input, spatial reasoning, math.
Temporal Lobe
Auditory processing, language comprehension (Wernicke's area), memory, emotion.
Occipital Lobe
Vision.
Central sulcus
Divides motor (front) & sensory (back) cortex.
Sylvian fissure
Divides temporal lobe from frontal/parietal.
Corpus callosum
Bridge between hemispheres.
Cingulate gyrus
Emotion & attention (part of limbic system).
Dura mater
Thick, tough outer layer ("tough mother").
Arachnoid mater
Middle, web-like layer; contains veins and CSF.
Pia mater
Thin, delicate layer that follows brain contours.
Somatotopic Maps
The motor and somatosensory cortices are organized by body region.
Contralateral control
Right brain → left body.
Photoreceptors
Rods (dim light, black & white) and cones (color, fine detail).
Fovea
Central focus point with dense cones.
Optic Chiasm
Where optic nerves cross; left visual field → right brain.
Dorsal Stream
V1 → Parietal lobe; spatial awareness, motion, location.
Ventral Stream
V1 → Temporal lobe; object & face recognition.
Receptive Field
Area of visual space that affects a given neuron's firing.
Lateral Inhibition
Retinal cells inhibit neighbors → enhances contrast.
Trichromatic Theory
3 cone types (red, green, blue).
Opponent-Process Theory
Pairs (red-green, blue-yellow, black-white).
Binding Problem
How does the brain combine sight, sound, touch, etc., into a unified perception?
Synchronous neural firing
Different sensory areas activate in rhythm when processing the same event.