Chapter 26 Urinary system

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what is the function of the urinary system?
it removes waste from your blood in the form of urine
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what is the function of kidneys?m
regulates blood ionic composition

blood pH

blood volume
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what structures make up the urinary system?
kidneys

renal pelvis

ureters

bladder

urethra
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what is a nephron?
a functional unit that consists of the renal corpuscle and real tubule
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What are the 2 nephrons?
cortical and juxtamedullary
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what are the basic process used by kidneys?
filtration and reabsorption
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filtration
uses nephron to filtrate
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reabsorption
movement of water and solutes from tubule back to plasma
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secretion
water and hydrogen ions pass from the capillaries into the renal tubule
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what are the 3 basic functions performed by nephrons?
filtration

reabsorption

secretion
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what is the filtration membrane and factors that promote it
glomerular and blood pressure/volume
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what are factors that control glomerular filtration?
capillary hydrostatic pressure

Bowmans space oncotic pressure
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what is the equation for net filtration?
NFP= GBHP-CHP-BCOP
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list 3 types of regulation for GFP
renal autoregulation

neural regulation

hormonal regulation
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route for tubular reabsorption
solutes are reabsorbed across the wall of nephron into interstitial fluid
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route for tubular secretin
solutes are secreted across the wall of nephron into the filtrate
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tubular reabsorption mechanism
osmosis
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tubular secretion
active transport and passive diffusion
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paracellular
passive fluid leakage between cells
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transcellular
directly through the tubule cells
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primary active transport
uses ATP like Na and K pump
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secondary active transport
driven by ions electrochemical gradient
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obligatory water reabsorption
90% water follows the solutes that are reabsorbed
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facultative water reabsorption
10% regulated by ADH
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what happens during reabsorption in PCT?
water and solutes within PCT are transported into the blood stream causing it to be isomotic
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symporters
move substances in same direction
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antiporters
move substances in opposite direction
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what is a nephron loop ?
something that conserves water for the organism and produces highly concentrated urine
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DCT duct
short tubule that regulate extracellular fluid volume and electrolyte homeostasis
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collecting duct
collects urine through it to the pelvis through ureters
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principal cells
reabsorb Na and secretes K
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intercalated cells
reabsorb HCO3 and secretes H
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what is the homeostatic regulation of tubular reabsorption and secretion
ADH and aldosterone
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5 hormones that affect the extent of Na, Cl, Ca2, and H2o
angiotensin II

ADH

aldosterone

ANP

PTH
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dilute urine
osmolarity in the tubule
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concentrated urine
osmotic gradient is created
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how does ADH affect urine concentration?
high ADH causes concentrated urine and low causes diluted urine
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countercurrent exchange
energy is used to create an osmotic gradient that enables reabsorption of water
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how does female and male urethras differ?
female is short and male is long
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how could kidney functions be evaluated?
blood urea nitrogen

plasma creatine

renal plasma clearance
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characters of urine?
pale yellow

odorless

pH of 4.5-8.0

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affects of kidneys with agin
shrunken kidneys

filtering less blood

decreased blood flow