Chapter 2: Tissue Response to Injury

Module 1

How does chronic pain differ from acute pain?

It persists longer than typical for a condition and may or may not be related to the acute injury.

What are the different types of pain?

Nociceptive, neuropathic, dysfunctional, and psychogenic.

Why are A-delta fibers able to respond to intense mechanical stimulation and heat or cold?

They are small-diameter, myelinated nerve fibers that rapidly transmit sharp, stabbing, or prickling sensations.

What type of sensations does C-fiber transmit?

Dull, throbbing, aching, burning, tingling, or tapping.

Which peripheral pathway can be blocked by opioids?

C fibers

Which peripheral pathway is inolved in nonpainful sensations related to vibration, stretching, and mechanical pressure?

A-beta fibers

How is pain transmitted?

Stimulus → Nociceptor → Peripheral Nerve → Spinal Cord → Brain → Perception (Pain)

What part of the spinal cord controls the passage of pain to the brain?

Dorsal horn, consists of inhibitory interneurons.

How does the body react to injury?

Muscle guarding, edema formation, and release of endogenous pain chemical mediators