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When do the AV valves open and close?
Open: when pressure is higher in atria compared to ventricles
Close: when pressure is higher in ventricles than atria
When do semilunar valves open and close?
Open: when the pressure is higher in the ventricle compared to the arteries
Close: when the pressure is higher in the arteries compared to the ventricles
role of septum
separates oxygenated and deoxygenated blood
maintains high conc. of O2 in oxygenated blood
to maintain conc. gradient to therefore enable diffusion at respiring cells
some babies are born with a hole between the right and left ventricles. suggest why these babies are unable to get enough oxygen to their tissues
mixing of oxygenated and deoxygenated blood
- therefore lower volume of oxygenated blood leaves the left ventricle and flows into the aorta
role of tendons
prevents inversion of valves due to high pressure
2 ways in which blood moves in one direction as it passes through the heart
blood moves down a pressure gradient
blood moves from high to low pressure
2. valves stop backflow of blood
structure of arteries
thick walls: enabling it to carry blood at high pressures
elastic tissue: smooths out blood flow and maintains pressure
muscles in wall: to control blood flow
smooth endothelium: to reduce friction
contrast the structure of arterioles and arteries
Arterioles have thicker muscle layer than arteries, which contract to control the flow of blood
Arterioles elastic layer is relatively thinner than the elastic layers in arteries, because blood pressure is lower
why is an arteriole described as an organ?
made up of different tissues/made up of more than one tissue
how do the muscle fibres in arterioles reduce blood flow to the capillaries?
the muscle contracts
so the arterioles narrows/constricts
vasoconstriction
structure of aorta
elastic tissue: to allow stretching/recoil to maintain pressure
elastic tissue stretches when ventricles contract
muscles: contraction/vasoconstriction
thick walls: to withstand pressure
smooth endothelium: to reduce friction
SLV: to prevent back flow of blood
suggest why the rise and fall in blood pressure in the aorta is greater than in the small arteries
aorta is directly linked to the heart, therefore the pressure is higher in the aorta than in the small arteries
aorta has elastic tissue, so it can stretch/recoil
describe the difference in the thickness of aorta wall during each time in cardiac cycle
1. during systole: aorta wall stretches bc ventricles contract
2. during diastole: aorta walls recoil bc ventricles relax
this helps maintain smooth blood flow
explain how the highest blood pressure is produced in the left ventricle
left ventricle has thicker, muscular walls
therefore stronger contractions
structure of veins
thin walls due to lower pressure, therefore requiring valves to ensure blood doesn’t flow backwards
less muscular and elastic tissue bc they don’t have to control blood flow
smooth endothelium to reduce friction
explain the difference in thickness between pulmonary artery and pulmonary vein
pulmonary artery contains muscle and elastic fibres
b/c pulmonary arteries handle high pressures and smooth out blood flow
structure of capillaries
permeable capillary membrane
thin, one-cell thick walls: short diffusion distance/pathway
small diameter: short diffusion distance
flattened endothelial cells: short diffusion distance
numerous and highly branched: provides large SA
narrow lumen: reduces blood flow rate to give more time for diffusion
advantage of capillaries being narrow
short distance b/w blood and the outside of the capillary
therefore fast diffusion
why is the blood flow in capillaries slow?
so that theres more time for diffusion
what factor limits the internal diameter of the lumen of a capillary?
width/diameter of blood cell
how can the widening of blood vessels reduce blood pressure
widening of blood vessels causes larger lumen, which reduces the blood pressure in blood vessels
therefore less friction/resistance in the blood vessels
suggest why pulse can be used to measure heart rate
pulse is caused by the pressure from one contraction/beat of the heart
role of heart in formation of tissue fluid
1. contraction of ventricles produces high hydrostatic pressure
2. this forces water and some dissolved substances out of the capillaries
how tissue fluid is formed and returned to circulatory system
high blood/hydrostatic pressure at arterial end of capillary which forces water out
large proteins remain
water potential in capillary becomes lower/negative due to these proteins
water potential now lower than hydrostatic pressure
so water enters venous end of capillary by osmosis
water moves out at the arteriole end and back in at the venule end
lymph system collects any excess tissue fluid which returns to blood/circulatory system
how does high blood pressure lead to an accumulation of tissue fluid
1. high blood pressure = high hydrostatic pressure
2. increases outward pressure from arterial end of capillary
3. more fluid forced out of capillary due to high pressure
4. so more tissue fluid formed
5. less return of fluid into capillary (due to high pressure)
Explain why a lack of protein in the blood causes a build up of tissue fluid.
water potential in the capillary is higher
- therefore less water removed by osmosis
suggest how an increase in volume of blood entering the heart reduces angina
1. large amount of blood leaves the heart
2. therefore more blood/oxygen flow to the heart muscle via coronary arteries
explain how blood in a vein in the leg is returned to the heart
1. muscles surrounding the vein contracts and press on the walls of the vein, squeezing blood along the veins
2. valves prevent backflow
3. contraction of heart pumpls blood through arteries into vein (systole)
4. the recoil of heart muscle after contraction/ during diastole draws the blood from the veins into the atria
5. veins have wide lumens therefore theres little resistance
how to calculate something with eyepiece graticule
measure using eyepiece graticule
calibrate eyepiece graticule against stage micrometer
take a number of measurements to calculate a mean