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What is the heart?
Cone shaped muscular pump (upside down pyramid)
Where is the heart located (simple)?
In the thorax between the lungs (middle mediastinum)
Location of the heart (complex)
Protected by ribcage
Lies behind sternum
Between ribs 2-5 (left of midline)
Apex found in 5th intercostal space, midclavicular line
What is the fibrous pericardium, where is it and and what purpose does it serve?
What: Inelastic sac of dense connective tissue
Where: Fuses inferiorly with the diaphragm and superiorly with the great vessels
Why: ‘Seatbelt’ - prevents overfilling of heart and anchors it into position
What is the serous pericardium, what does it consist of and what purpose does it serve?
Double layered serous membrane that lies deep to the fibrous pericardium. Contains Parietal and Visceral portions
Contains :
Parietal pericardium - lines inner surface of fibrous pericardium
Visceral pericardium (epicardium) - adheres tightly to surface of heart
Pericardial cavity - space between the two layers, contains tissue fluid
Function: Prevents friction
What are the 3 layers of the heart wall?
Endocardium : Inner layer - endothelium (simple squamous epithelium)
Myocardium: middle layer - cardiac muscle
Epicardium: outer layer - visceral pericardium
what are the two aortas?
Ascending aorta, Descending thoracic Aorta
What is the fibrous skeleton of the heart?
Bands of fibrous connective tissues between the atria and ventricles
What does the fibrous skeleton of the heart do?
Electrically seperates atria from the ventricles
Encircles the pulmonary trunk, aorta, semilunar and AV valves
What are the AV valves?
Tricuspid - right
Bicuspid - left
What are the semilunar valves?
Pulmonary
Aortic
What features do the AV valves have?
Anchored by chordae tendinae to papilllary muscles
What happens when the papillary muscles contract?
Prevents eversion of valves therefore backflow of blood into the atria
Where are the semilunar valves?
Guards entrances of aorta and pulmonary trunk
How much blood does the heart recieve every minute? (coronary circulation)
250ml
How is blood delivered to the heart?
To myocardium during ventricular relaxation
What does the left coronary artery (LCA) consist of?
Anterior interventricular
Circumflex
What does the right coronary artery consist of?
Marginal artery
Posterior interventricular
What is angiography and what can it detect?
Medical imaging technique used to examine the patency of vessels
restricted blood vessels - angina
What does the conducting system do and consist of?
Coordinates heart contraction
Consists of non-contractile cells that initiate electrical impulses
What does the conducting system consist of? (complex)
SA node
AV node
AV bundle (bundle of his)
Right and left bundle branches
Purkinje fibres
What does an electrocardiogram (ECG) do?
Records the electrical activity of the heart
Why is the foetal circulation different ?
Oxygen and nutrients received from placenta via umbilical vein
Need to bypass non-functional lungs
What are the 3 circulatory shortcuts of foetal circulation?
ductus venosus connects umbilical veins to inferior vena cava
Foramen ovale connects right and left atria
Ductus arteriosus connects pulmonary trunk to arch of aorta
What happens when a newborn takes its first breath?
Lungs expand → blood rushes into pulmonary circulation → O2 levels rise → constricts ductus arteriosus
LA pressure increases → Foramen ovale closes to become fossa ovalis
Umbilical cord ties → Umbilical vessels close → Ductus venosus fibroses