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Practice flashcards for Chapter 5: The Integumentary System, covering functions, layers, accessory structures, and common conditions.
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What are the four main functions of the integumentary system?
Protection, sensory function, thermoregulation, and Vitamin D synthesis
What two types of corpuscles are associated with sensory function in the integumentary system?
Pacinian and Meissner corpuscles
What happens to dermal blood vessels during strenuous physical activities to prevent overheating?
They dilate and sweat secretion increases
What happens to dermal blood vessels in response to low temperatures to minimize heat loss?
They constrict
What is the primary function of sweat secretion during strenuous activity in relation to thermoregulation?
It prevents the body from overheating
What are the two main sense receptors found within our dermis?
Meissner corpuscle and Pacinian corpuscle
Which dermal receptor is responsible for tactile or touch sensation?
Meissner corpuscle
Which dermal receptor responds to vibration?
Pacinian corpuscle
Where is a Meissner corpuscle typically located in a skin cross-section?
In a dermal papilla adjacent to the basement membrane and stratum basale of the overlying epidermis
What are the two main layers of the skin?
Epidermis and dermis
What type of cells is the epidermis made of?
Closely packed epithelial cells
What type of tissue is the dermis made of?
Dense, irregular connective tissue
What structures are housed within the dermis?
Blood vessels, hair follicles, sweat glands, and other structures
What layer lies beneath the dermis?
The hypodermis
What is the hypodermis mainly composed of?
Loose connective and fatty tissues
What type of epithelial cells is the epidermis made up of?
Keratinized, stratified squamous epithelial cells
What does 'stratified' mean in the context of the epidermis?
Many layers
What does 'squamous' mean in the context of the epidermis?
Flat
How many layers does the epidermis typically have?
4-5 layers
Where is 'thick skin' found on the body?
Palms of our hands and our feet
What is the main difference in thickness between thin and thick skin?
Thick skin has a significantly thicker epithelial layer
List the layers of the epidermis from deep to superficial in thin skin.
Stratum basale, stratum spinosum, stratum granulosum, stratum corneum
What is the deepest layer of the epidermis?
Stratum basale
What is the most superficial layer of the epidermis?
Stratum corneum
Which additional layer is found in 'thick skin'?
Stratum lucidum
Where is the stratum lucidum located in thick skin?
Between the stratum corneum and stratum granulosum
What are keratinocytes?
Cells that make and store the protein, keratin
In which layers of the epidermis are keratinocytes found?
All layers
What is keratin?
An intracellular fibrous protein that is waterproof
How is the epidermis described as an epithelium?
Keratinized stratified squamous epithelium
What type of cells are found in the basal layer of the epidermis?
Cuboidal cells
What type of cells are the outer layers of the epidermis composed of?
Squamous, keratinized cells
Which epidermal layer is the deepest?
Stratum basale
What is a key characteristic of cells in the stratum basale?
Cuboidal cells, highly mitotic
Which epidermal layer is the 4th from the bottom?
Stratum spinosum
What is a characteristic feature of cells in the stratum spinosum?
Spiny appearance, desmosomes
Which epidermal layer is considered the middle layer?
Stratum granulosum
What process begins in the stratum granulosum?
Keratinization
Which epidermal layer is 2nd from the top, exclusively found in thick skin?
Stratum lucidum
Describe the cells of the stratum lucidum.
Clear, flat, dead keratinocytes
Which epidermal layer is the most superficial?
Stratum corneum
What is a key characteristic of the stratum corneum?
Many layers of dead, flat keratinocytes, waterproof
Why is the dermis considered the 'core' of the integumentary system?
It houses blood and lymph vessels, nerves, hair follicles, and sweat glands
What are the two components or layers of the dermis?
Papillary layer and reticular layer
What type of tissue are both layers of the dermis made of?
Connective tissue
What fibers extend between the papillary and reticular layers of the dermis?
Collagen fibers
Which dermal layer includes the dermal papillae extending into the epidermis?
The papillary layer
Which dermal layer contains dense collagen fiber bundles?
The reticular layer
What determines the relative coloration of the skin?
The amount of melanin produced by melanocytes and taken up by keratinocytes
Where are melanocytes located?
In the stratum basale
What protein is responsible for skin coloration?
Melanin
What are moles?
Benign accumulations of melanocytes, or in some cases, melanomas
What is vitiligo characterized by?
Depigmentation resulting in lighter colored patches of skin
Name four accessory structures of the integumentary system.
Hair, nails, sweat glands, and sebaceous glands
Where do hair follicles originate?
In the epidermis
What differentiate into cells of the inner root sheath?
Basal cells of the hair matrix
What forms the outer root sheath at the base of the hair root?
Basal cells
What is the visible part of the nail that extends beyond the finger or toe?
Free edge
What is the fold of skin overlapping the side of the nail?
Lateral nail fold
What is the crescent-shaped whitish area at the base of the nail?
Lunula
What is another name for the cuticle, the small band of tissue protecting the nail root?
Eponychium
What is the fold of skin on the proximal side of the nail body?
Proximal nail fold
What is the hidden part of the nail embedded in the skin?
Nail root
What is the visible part of the nail, covering the nail bed?
Nail body
What lies underneath the free edge of the nail, securing it to the fingertip?
Hyponychium
What is another name for sweat glands?
Sudoriferous glands
What are the two types of sweat glands?
Eccrine and apocrine
Which type of sweat gland is primarily involved in thermoregulation and found all over the body (e.g., palms)?
Eccrine glands
Which type of sweat gland is larger than eccrine glands and located deeper in the dermis?
Apocrine glands
Where are apocrine sweat glands typically located?
Hairy locations like armpits and genital regions
Why does sweat from apocrine glands smell worse than eccrine sweat?
It is thicker
What is the primary composition of sweat released by eccrine glands?
Mostly water
When is sweat released from apocrine glands, besides the general locations?
When we are nervous or when our hormone levels spike
What is another name for sebaceous glands?
Oil glands
What is the function of sebaceous glands?
To lubricate and waterproof skin and hair
What substance do sebaceous glands generate?
Sebum
What is sebum's role?
Natural lubrication for dead keratinized cells of the stratum corneum
What is one of the first noticeable signs of aging in the skin?
Loss of elasticity
How does cell division change in the body with aging?
Slows down
How does metabolic activity change in the body with aging?
Slower
How does blood circulation change with aging?
Decreases
How do hormone levels change with aging?
Decrease
How does muscle strength change with aging?
Decreases
What happens to mitosis in the stratum basale with aging?
Decreased mitosis
What is the effect of decreased mitosis in the stratum basale on the epidermis with aging?
Thinner epidermis
Name a common inflammatory skin condition often characterized by dry, itchy patches.
Eczema
Name a common skin condition caused by over-productive sebaceous glands.
Acne
Name a chronic autoimmune skin condition that speeds up the growth cycle of skin cells.
Psoriasis
What is the most common disease for skin?
Cancer
What medical professional specializes in skin conditions?
Dermatologists
How often should an individual typically get a whole body skin scan?
At least once per year
Name the three main types of skin cancer.
Basal cell carcinoma, squamous cell carcinoma, and melanoma
Which type of skin cancer is readily cured if caught early?
Basal cell carcinoma
What serious type of skin cancer is characterized by the ABCDEs?
Melanoma
What does 'A' stand for in the ABCDEs of melanoma?
Asymmetry
What does 'B' stand for in the ABCDEs of melanoma?
Borders (irregular)
What does 'C' stand for in the ABCDEs of melanoma?
Color (varied or uneven)
What does 'D' stand for in the ABCDEs of melanoma?
Diameter (larger than 6mm)
What does 'E' stand for in the ABCDEs of melanoma?
Evolving (changes in size, shape, color, or elevation)
What causes acne formation?
Over-productive sebaceous glands