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Mutation
A random change in the base sequence of DNA; It is the source of new alleles
Allele
A version of a gene; New ones form through mutation
Gene
A section of DNA that codes for a specific protein
mRNA
A copy of a gene made in the nucleus; It carries instructions to the cytoplasm
Protein
A molecule made of amino acids; Synthesised at ribosomes based on mRNA
Ribosome
Organelle where amino acids are assembled into proteins based on mRNA
Nucleus
The part of the cell where DNA is stored and mRNA is made
Cytoplasm
The cell region where mRNA is translated and proteins are made
Sickle-cell
A genetic disorder caused by a mutation in the haemoglobin gene
Haemoglobin
The protein in red blood cells that carries oxygen; Altered in sickle-cell disease
Amino acid
The building block of proteins; Sequence is determined by mRNA
Base
A unit of DNA or RNA;
The order of these determines genetic code
Codon
A sequence of three RNA bases that codes for an amino acid
Enzyme
A protein that speeds up chemical reactions; Made using genetic instructions
Transcription
The process of copying DNA into mRNA in the nucleus
Translation
The process of building a protein from mRNA at the ribosome using specific amino acids;
the order of amino acids is given by the bases in the mRNA;