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Endocrine System
The system of the body that produces, circulates, and regulates hormones.
Kisspeptin
A brain chemical believed to trigger the onset of puberty
Leptin
A protein in our body that tells our body when we have enough fat.
Puberty
The period of adolescence transitioning to sexual maturity.
Adrenarche
The phase of maturation in the adrenal glands – when puberty is first turned on.
When does adrenarche start?
Around 9-10 years old
Why is the endocrine system essential to puberty/adolescence?
To regulate and monitor certain hormones from the central nervous system
Pituitary gland
The main gland in the endocrine system; facilitates growth and development
Gonads
Glands that secrete sex hormones.
What are parts of the endocrine system and the hormonal feedback loop?
Hypothalamus
Pituitary glands
Gonads
Sex hormones (androgens and estrogens)

Melotonin
A hormone that contributes to sleepiness and the trigger of onset puberty.
What triggers pubertal maturation?
Kisspeptin triggers the onset of puberty, and is stimulated by the protein of leptin and melatonin in the body
Why is leptin important in puberty development?
Leptin is needed to help the body regulate hunger and appetite
Leptin is essential for women in order to develop the correct body weight to carry a child
What are the earliest stages that both genders fully go through puberty?
Females: ~age 10
Males: ~age 12