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what must a ventilator maintain during inspiration
a constant pattern of flow, regardless of changes in patient compliance or resistance
what is the basic equation relating mouth pressure and flow
Pm = (flow × Raw) + PA
how can flow be expressed from this equation
Flow = (Pm − PA) / Raw
why does the Pm − PA gradient diminish across inspiration
due to time constants (compliance × resistance), inspiratory flow decays exponentially
at 3 time constants (3TC), what happens to Pm and PA
Pm = PA → deltaP = 0 → flow = 0
how does the ventilator control flow despite time constants
by using high internal ventilator resistance (Rvent)
what is the result of high Rvent
Pg ≠ Pm and time constants are extremely long (flow is controlled by ventilator)
how is 3 time constants calculated with Rvent
3TC = 3 × (compliance × (Rvent + Raw))
during ventilator-controlled flow, which pressure drives flow
driving pressure
what is the equation for flow under ventilator control
Flow = (Pg − PA) / (Rvent + Raw)
how is a time constant (TC) calculated in a ventilated patient
TC = compliance × (Rvent + Raw)
does flow decay according to lung time constants even with a flow controller
yes
why does flow not significantly decay during inspiration with a flow controller
Ti is much shorter than even one time constant, so flow doesn’t begin to decay
how does the ventilator maintain the set flow pattern
by continuously monitoring flow and adjusting internal resistance (Rvent) if the flow deviates
does the equation of motion change with a flow controller
no, it remains the same
what must the operator set when using a flow controller
a flow rate
what flow patterns can a flow controller maintain
square flow or decreasing flow
how does the ventilator respond to changes in lung characteristics
adjusts Rvent to maintain the set pattern; flow rate is unaffected
is the flow pattern maintained breath-to-breath
yes
what is the relationship between flow, volume, and time
Flow = volume / time
if flow is constant, what else is guaranteed
Vt and Ti are constant
what is the advantage of a flow controller over a pressure controller
Vt is guaranteed because it is a function of the set flow
how does the ventilator control flow in flow control mode
the ventilator controls the flow pattern, which is unaffected by changes in Cs or Raw
what happens to volume and inspiratory time if flow is controlled
Vt and Ti are constant and unaffected by lung characteristics
what is guaranteed in flow control mode
Vt
do changes in Cs or Raw affect tidal volume delivery in flow control
no
what happens to Pm in flow control mode
Pm increases across inspiration because the ventilator does not control pressure
what are Pmi and Pm
Pmi = initial mouth pressure; Pm = final mouth pressure
how is mouth pressure measured and displayed
the ventilator measures Pm throughout inspiration but only provides the highest value (Ppeak/PIP)
what is the equation for Pm
Pm = (flow × Raw) + (volume / compliance + PEEP)
what is Pmi at the start of inspiration
Pmi = (flow × Raw) + PEEP (since alveolar volume = 0)
how does Pm change as volume is delivered
increases until the set volume is delivered
what flow patterns are available in flow control mode
square flow and decreasing flow
how does the ventilator deliver flow in a square flow pattern
maintains a constant flowrate from the beginning to the end of inspiration
how does Pm change in a square flow pattern
increases linearly from the start to the end of inspiration
which pressure is displayed as Ppeak/PIP
the Pm at the end of inspiration
how does alveolar volume and pressure change in a square flow pattern
volume and alveolar pressure increase linearly
how is Ti calculated in a square flow pattern
Ti = Vt / flowrate
how does the ventilator deliver flow in a decreasing flow pattern
PIFR is set, then flow decreases linearly across inspiration
is decreasing flow affected by patient compliance or resistance
no, it remains a constant pattern
what is the final flowrate in a decreasing flow pattern
either a percentage of PIFR or 5 L/min, depending on the ventilator
how do Pm and PA behave in a decreasing flow pattern
they do not increase linearly and do not have a parallel relationship
how is Ti determined in a decreasing flow pattern
using tidal volume and average flowrate
how is average flowrate calculated
average flow = (peak flow + final flow) / 2
what does the flow vs time waveform look like in decreasing flow
a straight descending line
what does the volume vs time waveform look like in decreasing flow
a slightly curved line, not straight
what does the pressure vs time waveform look like in decreasing flow
not straight lines; Pm and PA curves approach each other across inspiration
when can Ppeak/PIP occur in a decreasing flow pattern
either at the beginning of inspiration or at the end of inspiration