list the biology core concepts
life evolves over time
structure & function are interrelated
life processes involve information flow
matter & energy are transformed
biology consists of complex systems
list the levels of biological organization from smallest to largest
atoms
molecules
cells
tissues
organs
organisms
populations
communities
ecosystem
biosphere
example of population
population of bears
example of communities
population of bears and foxes in the forest
example of ecosystem
the coral reef
example of unity on a macro scale
eyes
bones
organs
example of unity on a micro scale
cell structure
organelles
DNA
proteins
example of diversity on a macro scale
size
coloration
body shape & size
example of diversity on a micro scale
physiology
proteins
DNA sequence
charles darwin 2 ideas
descent with modification
natural selection
descent with modification
traits are passed down from generation to generation and sometimes undergo changes or modifications over time
natural selection
organisms with advantageous traits are able to produce more offspring that will pass on those traits
example of: life evolves over time
natural selection
genetic variation
mutations
example of: structure & function are interrelated
structure of bird wings are adapted for flight (shape, lightweight bones, feathers)
example of: life processes involve information flow
neurons transmit information to other cells in the body
example of: matter and energy are transformed
cellular respiration: cells convert glucose (energy) and oxygen into CO2 and H2O (matter)
example of: biology consists of complex systems
a human’s nervous system, respiratory system, cardiovascular system, etc
different pieces of evidence indicating that life derives from common ancestry
fossil records
anatomical features from different species
molecular evidence (genetics)
biogeography
conditions that are necessary for natural selection to occur
Variation: Differences in traits among individuals.
Heredity: Traits can be passed from parents to offspring.
Differential Reproduction: Not all individuals reproduce equally.
Environmental Pressure: Challenges to survival and reproduction.
Fitness: Traits that help survival and reproduction.
Selection Pressure: Advantageous traits become more common.
Time: Takes many generations for significant change.
Non-Random Reproduction: Reproduction influenced by specific traits.
Accumulation: Beneficial traits accumulate in the population.
Selective Advantage: Traits greatly improve survival and reproduction.
explain how natural selection can lead to two different populations with features that are uniquely adapted to their particular environment
species will develop unique adaptations due to their environment will become more prevalent over time, making them better suited to survive
types of selection
natural
sexual
viral
artificial
sexual selection
reproductive mate provides pressure
artificial selection
humans provide pressure
essential elements
required for organisms to survive, grow, and reproduce
list the essential elements
oxygen
carbon
hydrogen
nitrogen
calcium
mass number (superscript)
protons + neutrons
atomic number (subscript)
number of protons (identity of atom)
valence electron
electrons occupying outermost shell
valence electron shells capacity
1st shell: 2 electrons
2nd shell: 8 electrons
isotopes
same element, different number of neutrons
carbon-14
used to date archaeological samples
organisms incorporate carbon-14 in metabolism until death
half life: 5,000 years
how is carbon-14 used to estimate how long ago an organism died
by measuring the remaining carbon-14 in a sample and comparing it to the initial amount of carbon-14 in the atmosphere
Interpret how the position of an atom on the periodic table can be used to determine the atoms properties and chemical bonding patterns.
Atomic Number: identifier
Period: indicates energy level or electron shell in which an atom’s valence electrons are located
Column (Group): similar chemical properties because they have same # of valence electrons
Describe how Van der Waals interactions can occur within nonpolar substances.
occur through temporary charge fluctuations
induced dipole
Describe how the different properties of water help support life’s processes.
excellent solvent
allows chemical reactions to occur
high heat capacity
helps stabilize temperature within organisms
high heat of vaporization
allows cooling to regular body temperature (sweating)
co/adhesion
transport of water and nutrients in plants
surface tension
allows insects to walk on water & capillary action
density
ice forms on surface of water, insulating layers beneath
ionization and pH regulation
critical for enzymatic reactions and stability of systems
how to predict whether a substance will readily dissolve in water based on its chemical properties.
polarity
ions
hydrogen bonding
hydrophilic
Acid
produces H+ ions (proton donor)
Base
produces OH- ions (proton acceptor)
Describe the relationship between pH and hydrogen ion concentration
The relationship between pH and H⁺ concentration is inverse. As pH increases, H⁺ concentration decreases, and as pH decreases, H⁺ concentration increases.
(pH = -log[H+]
describe how polymers form
dehydration synthesis: extends/joins polymers together by removing water molecule
describe how polymers break down
hydrolysis: breaks down polymers by adding a water molecule
carbohydrate function
energy storage
cell structure
carbohydrate composition
Carbon, hydrogen, and nitrogen atoms
(CH2O)n
carbohydrate structure
mono/di/polysaccharides
linear or branched
protein function
enzymes
structural support
transport
immune defense
protein structure
amino acids linked by peptide bonds
consists of: amino group, carboxyl group, and R side chain
has primary, secondary, tertiary, and quaternary structures
protein composition
C, H, O, N, S
lipid function
energy storage
insulation and cushioning
cell membrane
lipid composition
C, H, O, and other elements
lipid structure
hydrophobic
phospholipids: glycerol + 2 fatty acid chains + phosphate group
triglycerides: glycerol + 3 fatty acids
nucleic acid function
info storage and transport
DNA/RNA
nucleic acid composition
C, H, O, N, P
nucleic acid structure
phosphate group (PO4)
sugar molecule
nitrogenous base (ACTG)
saturated vs unsaturated fats
saturated
no double bonds between carbon atoms
packs tightly = high melting point
solid at room temp
unsaturated
1/more double bonds between carbon atoms = kind/bend
can’t pack closely = low melting point
liquid at room temp
Describe how a phospholipid bilayer prevents the passage of certain materials and predict which materials are likely to cross a membrane based on their chemical properties.
phospholipid: hydrophilic head and hydrophobic tails
nonpolar (hydrophobic) can pass through
polar (hydrophilic) can’t pass through
primary structure
amino acids joined by peptide bonds
secondary structure
alpha helices and beta sheets form in polypeptide chain, stabilized by hydrogen bonds
tertiary structure
3D arrangement of all amino acids in a polypeptide chain
determined by interactions among side chains (R-groups)
quaternary structure
structure of proteins composed of two or more polypeptide chains
DNA vs RNA
Genetic Information
DNA: carries gene info
RNA: carries out instructions based on gene info
Sugar
DNA: deoxyribose sugar
RNA: ribose sugar
Base
DNA: thymine
RNA: uracil
Strands
DNA: 2
RNA: 1
Function:
DNA: genetic info
RNA: gene expression, protein synthesis
plasma membrane
regulates passage of molecules in/out of cell
cytoplasm
gel-like substance within cell membrane where various cellular processes occur
genetic material
Prokaryotes: DNA in nucleoid region
Eukaryotes: DNA in nucleus
ribosomes
responsible for protein synthesis
found in cytoplasm or attached to ER
cytoskeleton
network of protein filaments that provides structural support and helps maintain cell shape
made of: microfilaments, intermediate filaments, microtubules
cell wall
rigid outer layer that provides structural support
flagella and cilia
hair-like structures on outside of cell surface used for movement and/or sensing the environment
mitochondria
energy production
endoplasmic reticulum
protein synthesis and lipid metabolism
golgi apparatus
protein modification and packaging
lysosomes
digestion
Place different structures in order of increasing size.
ribosomes
plasma membrane
cytoskeleton
flagella/cilia
eukaryotic cell organelles
nucleus
light microscopy
uses visible light
benefit: less expensive, specimen can be alive
disadvantage: many cellular structures not visible
electron microscopy
uses electrons
benefits: visual small structures
disadvantages: expensive, can’t use live specimen
scanning electron microscopy
focus bean of electrons onto specimen to create 3D image
transmission electron microscopy
focuses beam of electrons through specimen
characteristics of eukaryote cells
large size
single/multicellular
membrane-bound organelles
nucleus inside DNA
some have cell wall (plants)
characteristics of prokaryote cells
small size
unicellular
no membrane-bound organelles
no nucleus
most have cell wall
similarities between eukaryotic and prokaryotic cells
plasma membrane
cytosol
chromosomes
ribosomes
organelles unique to eukaryotes
nucleus
golgi complex
endoplasmic recticulum
mitochondria
lysosome
organelles unique to prokaryotes
capsule
DNA in nucleoid
certain features that enable these eu/prokaryotes to achieve reproductive success.
Eukaryotes
membrane-bound organelles allows specialization of functions within cell
mitosis and meiosis
sexual reproduction: genetic diversity
Prokaryotes
rapid reproduction
efficient resource utilization
genetic adaptability
endosymbiotic theory
some of the organelles in today’s eukaryotic cells were once prokaryotic microbes
endosymbiotic theory evidence
Membranes: some have double membranes
Antibiotics: susceptible to antibiotics
Division: reproduction occurs via a fission-like process
DNA: has own DNA (naked and circular)
Ribosomes: has own ribosomes
(Many apply to mitochondria and chloroplasts)
characteristics unique to plant cells vs. eukaryotic
rigid cell wall
chloroplasts
large central vacuuole
how does shape of a cell affect its surface-area to volume ratio
spherical shape
low surface area to volume ratio
limited transfer of materials across surface
more storage
irregular shapes
high surface area to volume ratio
increases transfer of materials across surface
less storage
which shape in nature is used more?
nature uses irregular shapes to maximize interactions w/ the environment
functions for a high surface area to volume ratio
nutrient absorption
gas exchange
photosynthesis
filtration
heat dissipation
Ex: cells, microorganisms, roots
functions for a low surface area to volume ratio
storage
protection
insulation
slow metabolism - to conserve energy
Ex: elephant ears, succulents, deep sea fish
components that make up the endomembrane system
nuclear envelope
smooth & rough ER
golgi apparatus
vesicles
lysosomes
vacuoles (in plants)
nuclear envelope
double membrane that surrounds cell’s nucleus
contains nuclear pores that allow exchange of materials between nucleus and cytoplasm
endoplasmic recticulum
rough ER:
involved in protein synthesis, folding, and processing
has ribosomes on surface
smooth ER:
involved in lipid synthesis, detoxification, and calcium ion storage
no ribosomes
golgi apparatus
flattened membrane sacs that receive, modify, and package proteins and lipids produced by the ER
sorts and directs molecules to their appropriate destinations within or outside cell
vesicles
small membranous sacs that transport materials between the different components of the endomembrane system and to other cellular locations
Ex: transport vesicles
lysosomes
membrane-bound organelles containing digestive enzymes
breaks down cellular waste, debris, and foreign materials (through autophagy)
vacuoles
large membrane-bound sacs found in plant cells that store water, nutrients, and waste products; can also play a role in maintaining turgor pressure and supporting the cell’s structure
why does the endomembrane system represent a separate compartment within cells
membrane barriers
specialized functions
material processing and transport
isolation of reactions
why are certain proteins synthesized in different places within the cell
the synthesis of proteins in different places is a highly regulated and organized process that ensures proteins are produced, modified, and directed to the appropriate cellular locations to perform their specific functions
process of the endomembrane system
synthesis of molecules (can be free in cytoplasm or attached to ER)
enter the ER
newly synthesized proteins bud off from ER then fuse to gogli apparatus
inside golgi: proteins undergo additional post-translational modifications or sorts proteins/lipids into vesicles
vesicles containing sorted materials bud off and transported to final destination (can fuse with other organelles/cell membrane, releasing contents or into extracellular space)
key features of fluid-mosaic model
fluidity of individual lipid molecules
consists of lipids, proteins, and carbohydrates
lipid bilayer & its fluidity
proteins embedded within lipid bilayer
cholesterol stabilizes the membrane