Immunology Exam 3- Hypersensitivity Comparison Chart
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Last updated 10:17 PM on 4/12/23
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31 Terms
1
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How many hypersensitivity reactions are there?
4
2
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What types of hypersensitivity reactions involve antibodies?
1, 2, 3
3
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What type of hypersensitivity reaction involves T cytotoxic cells?
4
4
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What is hypersensitivity?
immunological reaction that may result in a damaging excessive overreaction following secondary exposure to antigen
5
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What antibody is associated with type I reactions?
IgE
6
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What antibodies are associated with type II reactions?
IgG and IgM
7
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What antibodies are associated with type III reactions?
IgG and IgM
8
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What antibodies are associated with type IV reactions?
none
9
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What antigen is associated with type I reactions?
exogenous antigens
10
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Define exogenous
originating from outside an organism
11
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What antigen is associated with type II reactions?
cell surface
12
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What antigen is associated with type III reactions?
soluble
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What antigen is associated with type IV reactions?
cellular
14
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What is the response time for type I reactions?
15-30 minutes
15
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What is the response time for type II reactions?
minutes to hours
16
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What is the response time for type III reactions?
3-8 hours
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What is the response time for type IV reactions?
48-72 hours or longer
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What is the appearance of type I reactions?
weal and flare
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What is the appearance of type II reactions?
lysis and necrosis
20
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What is the appearance of type III reactions?
erythema (reddening) and edema
21
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What is the appearance of type IV reactions?
erythema and induration (thickening and hardening of soft tissue)
22
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What is the histology of type I reactions?
basophils and eosinophils
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What is the histology of type II reactions?
AB and complement
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What is the histology of type III reactions?
PMN and complement
25
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What is the histology of type IV reactions?
monocytes and lymphocytes
26
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What reactions are transferred with antibody?
Type I, II, III
27
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How are type IV reactions transferred?
T-cells
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What are examples of type I reactions?
hay fever and asthma
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What are examples of type II reactions?
pemphigus (blistering of skin/cavities) and good pasture (produce antibodies that attack the lungs and kidneys)
30
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What are examples of type III reactions?
farmer’s lung and SLE (lupus)
31
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What are examples of type IV reactions?
TB test, poison ivy, granuloma
Note 
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