13 benign non-odontogenic tumors

Unknown

Causative agent for ossifying fibroma

Ossifying fibroma

This tumor can occur in any facial bone and has the potential for excessive growth, bone destruction, and recurrence

Mandible

part of jaw where ossifying fibroma affects the msot

Juvenile ossifying firboma

What varient of ossifying fibroma is rapid growth seen in children?

Manidublar premolar area

iN ossifiying fibrma, jaw lesions would rise in too bearing regions such as?

Well-circumscribed, sharply defined border

IN radiograph what is the appearnce of ossifiyng fibroma

surgical removal `

Treatment for ossifiyng fibroma

Fibrous dysplasia

a condition in which normal medullary bone is replaced by an abnormal fibrous connective tissue proliferation in which new, nonmaturing bone is formed.

-Monostotic fibrous dysplasia

-Polyostotic fibrous dysplasia

List the two types ofibrous dysplasia

Displacement of teeth

What occurs with fibrous dysplasia?

Radiolucent to radiopaque (Ground glass or peau d orange effect)

in radiograph of fibrous dysplasia, what is the appearance?

Confirmatory biopsy

Treatment for small lesion fibrous dysplasia

surgical correction (cosmetic and functional deformaties)

TReatment for large lesion fibrous dysplasia

-Bisphophonates

-monoclonal antibodies

-RANKL (denosumab)

Treatment for fibrous dysplasia- reported to improve symptoms of pain and bone density

Osteoblastoma/ Osteoid osteoma

What cyst arise from vertebrea and long bone?

posterior tooth-bearing regions (MAX AND MANDI)

what are the usual sites of osteoblastoma/osteoid osteoma

-Medullary

-Periosteal sites

What 2 other sites does the osteaoblstoma/osteoid osteoma arise from?

Osteoid Osteoma

WHat cyst is pain usually assocaited with?

Osteoblastoma

Osteoid Osteoma

-Aspirin

-NSAIDs

2 Drugs used for relief of nocturnal pain associated with osteoid osteoma

Conservative surgery (curretage or local excision)

Treatment for osteoblastoma/ osteoid osteoma

Mature, compact, cancellous bone

What does Osteoma consist of?

Periosteal osteomas

type of osteomas that arise on the surface of bone; asymptomatic, slow-growing, bony, hard masses; asymmetry

Endosteal or solitary central osteomas

Type of osteoma that develop centrally within bone; discovered during radiographic examination; well-circumscribed radiopacities; extensive growth must take place before cortical expansion is evident

Gardner syndrome

What syndrome in which there are multiple osteomas?

Surgical excision

Treatment for osteoma if symptomatic and for confirming diagnosis

Small asymptomatic osteomas

Treatment for osteoma for periodic observation

dESMOPLASTIC FIBROMA

Locally aggressive lesion of the bone; may suggest a neoplastic process

Long bones and pelvis

In desmopalstic fibroma, it usually appears where?

Unknown

Cause of desmoplastic fibroma

Jaw swelling

In desmoplastic fibroma, what happens after slowly progressive and asymptomatic?

Unilocular & Multilocular

In radiograph, waht is ithe appearance of desmopasltic fibroma?

Surgical resection

Treatment of choice for desmoplastic fibroma

Curettage alone

Treatment of desmopalstic fibroma when associated with significant recurrence rate

Chondroma

This cyst is a benign cartilaginous tumor of unknown cause

Mucosal ulceration

In chondroma, it is a gradual expansion of lesion results in?

-nasal septum

-Ethmoid sinuses

Areas where chondroma present

maxillary-anterior region

In chondroma, it is the region where cartilaginous remannt of development are lcoated ?

-Body and symphysis

-Coronoid

-COndylar processes

In chondroma, what parts of the mandible is affected?

Surgical excision

Treatment for chondroma

Central Giant Cell granuloma (CGCG)

a benign proliferation of fibroblasts and multinucleated giant cells within a well vascularized stroma that occurs almost exclusively within the jaws.

-Fibroblasts

-MUltinucleated giant cells

IN CGCG, what cells are being proliferated?

Osteoclast like feature

IN multinucleated cells, what is the most prominent feature?

Benign neoplasm

CGCG is best considered as a what?

Surgery (excision or curettage)

TReatmeant for CGCG

RANK ligand antibodies (denosumab)

TReatment of CGCG that is useful targeting osteoclast like giant cells

Giant cell tumor

true neoplasms that arise most commonly in long bones, especially in the area of the knee joint.

3rd and 4th dewcades of life

When does giant cell tumor affect?

Long bone

In giant cell tumor, where does it most commonly arise in?

-Ethmoid

-Sphenoid

-Temporal

In giant cell tumor, what other sites is it present?

-Rapid growth

-Pain paresthesia

iN giant cell tumor, what would they produce?

Surgical excision

-Anti-osteoclastigenic drugs

TReatment for giant cell tumor

Radiolucent

In radiograph, what is the appearance of giant cell tumor?

Hemangioma of bone

rare intraosseous vascular malformations • when seen in the jaws, can mimic both odontogenic and nonodontogenic lesions

Difficult to control hemorrhage

IN hemangioma of bone, what is a notable complcation of surgical intervention?

Mnadible-posterior region

What region does hemangioma of bone affect?

-spontaneous gingival bleeding aroudn teeth

What occurs in the are of hemongioma of bone?

resorption of rooth of teeth

In hemangioma of bone, what may produce?

Needle aspiration

TReatment for hemangioma of bone that may be vascular of origin

Langherhan's cell disease

spectrum of disorders characterized by a proliferation of cells exhibiting phenotypic characteristics of Langerhans cells

myeloid dendritic cell-bearing markers (CD1Aa and CD207)

In langerhan's cell disease, what is the cell of origin

Chemotherapeutic agents

-Allogenic bone marrow transplantation

Treatment for langerhan's cells disease

Tori and exostoses

nodular protuberances of mature bone; their precise designation depends on the anatomic location

Torus palatinus

type of varient of tori that is a sessile, nodular mass of bone that appears along the midline of the hard palate. The palatal torus usually appears during the second or third decade of life

Torus mandibularis

Type of tori where bony exophytic growths that appear along the lingual aspect of the mandible superior to the mylohyoid ridge;asymptomatic, exhibiting slow growth during the second and third decades of life; Mandibular tori may arise as solitary nodules or as multiple nodular masses that appear to coalesce, no gender predilection

Surgical removal

TReatment for tori

Exostoses

multiple (or single) bony excrescences that are less common compared with tori

Exostoses

asymptomatic bony nodules that are present along the buccal aspect ofalveolar bone.

Maxilalr yand mandible

parts of the jaw where exostoses affects

NONE

TReatment for Exostoses

Coronoid hyperplasia

This type of cyst is uncommon and assocaited with limited mandibualr motion

Uknown

Causative agent for coronoid hyperplasia

Mishapen or mushroom shaped coronoid processes

In unilaterla coronoid hyperplasia, what does it result?

Hyperpalstic process

Coronodi enlargement appears to represent a what?

Surgical excision-> post-op physiotherapy

Treatment for coronoid hyperplasia