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Visceral effectors
smooth muscle, cardiac muscle, and glands. They are associated with the viscera (internal organs) of the body.
Dual innervation
organs will receive nerves from both the parasympathetic and sympathetic nervous system. One branch increases activity, the other decreases activity of the organ.
Preganglionic neuron
cell body is in the brain or spinal cord. Its axon exits the CNS via a cranial or spinal nerve and then extends to an autonomic ganglion.
Autonomic ganglion
synaptic site where preganglionic neuron synapses with the postganglionic neuron
Postganglionic neuron
second neuron, lies entirely in the PNS. Its cell body is located in the autonomic ganglion, and its axon extends from the ganglion to the visceral effector.
Terminal ganglia
where parasympathetic preganglionic axons extend to postganglionic neurons located close to or within the wall of the visceral effector.
Sympathetic trunk
chain of ganglia located on either side of the spinal cord
collateral ganglia
individual ganglia that are no associated with the sympathetic trunk.
Chromatin cells
they are modified sympathetic postganglionic neurons that lack dendrites and axons. specialized cells in the adrenal medulla that preganglionic axons extend to. They also realize hormones into the blood.
Neuroeffector junction (NEJ)
synapse between an autonomic postganglionic neuron and a visceral effector.
Varicosities
swollen regions at the terminals of postganglionic neurons which contain synaptic vesicles with neurotransmitters.
Cholinergic neuron
release neurotransmitter acetylcholine
Cholinergic receptors
Integral membrane proteins in the postsynaptic plasma membrane which ACh binds to.
Acetylcholinesterase (AChE)
enzyme that degrades acetylcholine
Monoamine oxidase (MAO)
enzyme that inactivates norepinephrine
Autonomic tone
balance between parasympathetic and sympathetic activity. regulated by the hypothalamus
Autonomic (visceral) reflexes
fast, involuntary responses that occur when action potentials pass through an autonomic reflex arc. They play a key role in homeostasis by regulating cardiovascular activities, digestion, defecation, and urination.
Neuromuscular junction (NMJ)
synapse formed between a somatic motor neuron and a skeletal muscle fibre
Motor end plate
region of the muscle fibre plasma membrane opposite the synaptic end bulbs
Junctional folds
deep grooves in the motor end plate that provide a large surface area for ACh.
End plate potential (EPP)
depolarization caused by the net influx of NA+ into the muscle fibre through the nicotinic ACh receptors. Type of graded potential which forms at synapses.
Muscle action potential
depolarization caused by inflow of Na+ into the muscle fibre through open voltage-gated Na+ channels