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Arteries
Carry blood away from the heart.
Arteries Structure
Composed of distinct layers.
Arteries Layers
Outer and inner layers primarily made of elastic and fibrous tissue.
Middle Layers of Arteries
Made up of smooth muscle tissue.
Arteries Function
Expand to accommodate the inrush of blood.
Pulse
Change in the pressure of blood following heart contractions.
Pulse Location
Can be felt near your wrist and on the neck.
Arterioles
Small blood vessels that lead to capillaries.
Autonomic Nervous System
The part of the nervous system that controls the motor nerves that regulate equilibrium.
Vasoconstriction
Narrowing of blood vessels, allowing less blood to flow to the tissues.
Vasodilation
Widening of blood vessels, allowing more blood to flow to the tissues.
Atherosclerosis
A degeneration of blood vessels caused by the buildup of plaque in the inner wall.
Arteriosclerosis
Hardening of the arteries that cause the blood to flow less efficiently.
Consequences of Arteriosclerosis
Can narrow arteries and can cause heart attacks.
Blood Clots
Can form in narrowed or blocked arteries.
Heart Disease Statistics
Every year, heart disease affects millions of people.
Heart Disease Prevention
Healthy lifestyle choices are keys to prevention.
Aneurysm
An abnormal bulge in a blood vessel wall.
Common Sites for Aneurysm
Most common sites include the aorta and brain.
Causes of Aneurysm
Most commonly caused by high blood pressure.
Aneurysm Consequence
An aneurysm in the brain can cause a stroke.
Signs of Stroke
Weakness, trouble speaking, vision problems, headache, dizziness.
Stroke Response
If you experience any of these symptoms, CALL 9-1-1 or your local emergency number immediately.
Capillaries
Red blood cells must travel through capillaries in single file.
Capillary Thickness
Only one cell thick.
Capillaries
Site of exchange between blood and body cells.
Capillary Beds
Capillary beds are networks of capillaries that facilitate exchange.
Oxygen Rich Blood
Oxygen rich blood appears bright red.
Oxygen Poor Blood
Oxygen poor blood appears dark red.
Deoxygenated Blood Collection
Deoxygenated blood collects in small veins called venules and is carried back to the heart.
Veins and Venules Walls
Walls contain valves.
Venules Merging
Venules merge into larger veins.
Blood Flow Changes
As blood flows from arteries to arterioles to capillaries, blood flow decreases and blood pressure in these smaller vessels drops.
Pressure Insufficiency
The pressure is not great enough to push blood back to the heart.
Veins Structure
Veins have valves, steering blood back to the heart.
Skeletal Muscles Role
Skeletal muscles aide in blood flow in veins by contracting and directing blood flow toward the heart.
Layers of the Heart
The layers of the heart include the pericardium (sac around the heart for protection), myocardium (middle layer, cardiac muscle), and endocardium (inside layer, protective).
Electrical Conduction of the Heart
Heartbeat
Heart Sounds
LUB - slamming of atrioventricular valves (tricuspid & bicuspid valves); DUB - slamming of semilunar valves (pulmonary & aortic s.l valves).
Intrinsic Heartbeat
Heart beats intrinsically (autonomously - not stimulated by external nerves - will continue to beat outside of the body for a short period on its own).
SA Node
Heart rhythm set by the SA node (sinoatrial node) in the upper right atrium - also called the 'natural pacemaker'.
Nerve Stimulation of SA Node
The vagus nerve stimulates the SA node. Sympathetic nervous system stimulation will speed it up and parasympathetic nervous stimulation will slow it down.
AV Node Function
Electrical impulse travels to the AV node (atrioventricular node) which causes contraction of the ventricles.
Impulse Conduction Pathway
Then the impulse is passed along to the bundle of His, then to the Purkinje fibers which super conduct the impulse through the ventricles.
Tachycardia
Tachycardia - SA signals speed up, resulting in an increased heart rate.
Bradycardia
Bradycardia - SA signals slow down, resulting in a decreased heart rate.
Pacemaker
Pacemaker - device to help set the heart rate.
Blood Pressure Definition
Any fluid confined in a vessel (hose or vein) exerts a push against the walls that contains it (blood pressure).
Narrowing of Blood Vessel
If the blood vessel narrows, the pressure of the fluid increases.
Expanding Blood Vessel
If the blood vessel expands in diameter, the pressure inside it decreases.
Increased Blood Volume Effect
If the volume of blood goes up, pressure will increase.
Decreased Blood Volume Effect
If you lose blood volume (bleeding), pressure will decrease.
Blood Pressure Facts
Blood pressure is highest at the heart and decreases as you move away from it.
Heart Rate Factors
Any factor that speeds your heart rate will increase blood pressure.
Arteries Control BP
Your arteries can control blood pressure by changing diameter according to your body's need.
Blood Pressure
Affected by cardiac output and vessel diameter.
Normal BP
Around 110/70-120/80.
Systolic Pressure
The pressure in the arteries during heartbeats.
Diastolic Pressure
The pressure in the arteries when the heart rests between beats.
High blood pressure readings
Readings above the normal range.
Low blood pressure readings
Readings below the normal range.
Hypertension
High blood pressure risk factors.
Blood Pressure Regulation
Regulated by the medulla oblongata in the brain.
Low BP Effects
Reduces capacity to transport oxygen in tissues.
High BP Effects
Over time it damages artery and capillary walls.
Blood Pressure Negative Feedback Loop
A mechanism to maintain BP within normal range.
Blood Pressure Receptors
Found in the walls of arteries, sensitive to pressure.
Medulla Oblongata
Sends messages to lower heart rate when BP is high.
Arterioles
Will dilate when BP is too high.
Heart Rate
Number of beats per minute, affected by nerve stimulation and hormones.
Cardiac Output
Amount of blood pumped by the heart per minute.
Stroke Volume
Amount of blood pumped with each beat (~70 ml per beat).
Cardiac Output Formula
Cardiac Output = Stroke Volume X Heart Rate.
Patrick's Cardiac Output
150 beats per minute at 70 ml per beat results in 10500 ml/min.
Thermoregulation
Maintenance of body temperature.
Normal Body Temperature
Approximately 37℃.
Hypothalamus
Regulates body temperature.
Sweating Mechanism
Sweat evaporates, cooling the body.
Vasodilation
Blood vessels near the surface widen to release heat.
Cold Temperature Response
Blood vessels constrict to reduce heat loss.
Goosebumps
The response of body hairs standing on end due to nerve messages from the hypothalamus.
Heat loss prevention
Heat is trapped under the hairs, helping to reduce heat loss, most effective with hairy animals.
Rhythmic contractions
Contractions initiated by the hypothalamus that help in thermal energy regulation.
Capillary Fluid Exchange
The process where capillaries provide cells with nutrients and are associated with fluid exchange between blood and tissue.
Blood circuit
The path blood travels, starting from arteries.
Capillary blood flow
Blood moves through capillaries very slowly, allowing time for material exchange.
Diffusion
The process by which water, sugar, amino acids, wastes, hormones, and vitamins move in and out of capillaries.
Osmotic pressure
The pressure that moves water from tissue fluid into blood, with a constant of 25 mm of Hg.
Blood pressure
The pressure that moves water from blood into tissue fluid, ranging from 35-40 mmHg at the arteriole end to 10-15 mmHg at the venule end.
Outward flow of water
The movement of water and small mineral ions out of the capillaries.
Selectively permeable
A characteristic of capillaries that allows certain substances to pass through while blocking others.
Fluid movement regulation
The process by which large proteins draw water back into the capillaries.
Fluid movement into capillaries
The process known as reabsorption.
Concentration of solutes
The level of solutes in the blood that can affect fluid movement.
Lymphatic System
A system that captures excess fluids leaked from capillaries and returns proteins to the bloodstream.
Lymph
Fluid that is collected from excess fluids leaked from capillaries and products of fat digestion.
Lymphatic vessels
Vessels that capture excess fluids and transport lymph, flowing one way only.
Lymph nodes
Masses of lymphatic tissue found at intervals along lymph vessels.
Lymphocyte
A type of white blood cell involved in the immune response.
Red Bone Marrow
The tissue where blood cells are produced.