NSG 116 Drug Therapy for Coagulation Disorders

What is hemostasis

The prevention or stoppage of blood loss from an injured blood vessel

Mechanisms involved

1)constriction of the blood vessel

2)formation of a temporary platelet plug

3)activation of clotting factors

4)formation of the final clot or fibrin plug to stabilize and repair

Platelet

Helps form clots and stop/prevent bleeding

Thrombosis

The formation of a blood clot

Thrombosis

The formation of a blood clot

Thrombus

A blood clot

Embolus

A thrombus (bloodclot) that detaches and travels

Thrombolysis

The dissolution of blood clots

Medication category

Anticoagulants

Anti platelets

Thrombolytics

Anticoagulants

Medications that decrease the ability for blood to clot

Anticoagulants Include

Heparins

Vitamin k antagonist

Direct thrombin inhibitors (DTIs)

Direct factor Xa inhibitors

Antiplalelet

Prevents platelets from clumping and prevents more blood clots from forming and growing in size

Thrombolytic

Dissolves blood clots quickly

True or false, hemostasis is a pathological condition with excessive bleeding

False,hemostasis is the normal physiological process that stops bleeding

In explaining the use of warfarin (Coumadin) to a client. The nurse is correct in telling them…

Warfarin is a vitamin K antagonist

Warfarin is metabolized by the liver

Warfarin is used for long term anticoagulation therapy