1. Avascular 2. Cells are chondrocytes found in lacunae 3. Three types - Hyaline - Elastic - Fibrocartilage
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Avascular
No blood vessels
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Cartilage Tissue Functions
1. Support soft tissues 2. Model for formation of bone 3. Gliding surface at articulations
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Is cartilage soft bone?
NO
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Hyaline Cartilage
1. Most common 2. Contains nearly invisible collagen fibers (fibrils) 3. Found in - Ends of long bones - Costal cartilages - Articular joint cartilage - Respiratory structures (larynx, trachea) - Fetal/embryonic skeleton
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Elastic Cartilage
1. Similar to hyaline cartilage 2. Contains lots of elastic fibers 3. VERY resilient and flexible 4. Tolerates repeated bending 5. Found in - Pinna (outer ear) - Epiglottis
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Fibrocartilage
1. Contains little ground substance 2. Matrix has thick, dense collagen fibers 3. Resists strong compression 4. Found in - Intervertebral disks - Knee joint - Pubic symphysis - Meniscus
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Cartilage Locations Diagram
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Fibril
1. Very thin fibers 2. Found in hyaline cartilage
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Bone Tissue
1. Very little fluid 2. Resists compression and tension; very strong 3. Well vascularized - Heals/remodels easily 4. Organic and inorganic materials 5. Osteocytes in lacunae
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Lacunae
Contains osteocytes
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Osteocytes
1. Found in lacunae 2. Mature bone cells 3. Can also be osteoblasts and osteoclasts
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What is the extracellular matrix of bones?
1. Organic - Fibers (lots of collagen) - Ground substance 2. Inorganic - 65% mineral salts - Calcium phosphate
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Osteoblast
1. A cell from which bone develops 2. Builds new bone
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Osteoclast
1. Cells that breakdown and consume bone tissue 2. Break down or consume bone
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Intramembranous Ossification
1. The process of forming bones within a membrane 2. Forms - Flat bones - Bones of the skull - Clavicle - Maxillae - Zygomatic mandible
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Endochondral Ossification
1. The process of forming bones most bones go through 2. Forms - Long bones of the axial skeleton - Appendicular skeleton
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Endochondral Ossification Steps
1. Skeleton begins as hyaline cartilage model 2. Primary center of ossification appears in diaphysis and bone replaces cartilage 3. Secondary center of ossification form in epiphyses 4. Skeleton grows via division of cartilage (and bone) cells until maturity 5. Epiphyseal (growth) plates ossify
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Primary Center for Ossification
1. Appears in diaphysis 2. Bone replaces cartilage
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Secondary Center for Ossification
1. Forms in epiphyses 2. Skeleton continues to grow via division of cartilage (and bone) cells until maturity
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Spongy Bone (trabecular bone)
1. Internal (deep) portion of bones 2. Surrounded by marrow 3. Typically near joints 4. More air pockets than compact bone 5. Good shock absorption
1. Structural unit of compact bone 2. Made up of concentric tubes called lamellae 3. Oriented parallel to the long axis and main compression stresses 4. Haversian (central) canal runs through core
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Haversian (central) Canal
1. Found in compact bone 2. Located inside osteons 3. Provides - Blood supply - Nutrients - Nerves
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Lamellae
1. Found in compact bone 2. Concentric tubes that make up osteons
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What is the structure of a long bone?
1. Epiphysis 2. Epiphyseal line 3. Diaphysis 4. Compact bone 5. Spongy bone 6. Periosteum 7. Endosteum 8. Medullary cavity 9. Nutrient arteries 10. Articular cartilage
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Epiphysis
End of a long bone
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Epiphyseal Line/Plate
1. AKA Growth plate 2. Hyaline cartilage plate 3. Found in epiphysis at each end of a long bone 4. In people who have stopped growing, the plate is replaced by an epiphyseal line
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Diaphysis
Shaft of long bone
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Periosteum
1. Outer membrane on bone long bone 2. Well supplied with nerves and blood vessels 3. Provides a place for tendons and ligaments to attach to bone
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Endosteum
1. Vascular membrane 2. Lines internal cavity of long bones
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Medullary Cavity
1. Bone marrow 2. Lined by endosteum
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What is the structure of flat, irregular and short bones?
1. Compact bone with periosteum on the outside 2. Spongy bone with endosteum on the inside 3. Contain marrow but DO NOT have a marrow cavity
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Closure of Epiphyseal Plates
1. Cartilage is gradually replaced by bone tissue on both sides of the epiphyseal plate (primary and secondary center of ossification) 2. Centers of ossification meet at the epiphyseal plate 3. Growth stops
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Bony Callus
1. If injured, cells tend to overgrow at an injury site 2. Forms a bony callus from the overgrowth of the osteoblasts
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How often do bones go through remodeling?
1. Bone continually undergoes remodeling 2. This is when cells break down/build bone
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Osteoporosis
1. Results from an imbalance of bone remodeling - More bone is broken down than new bone is built 2. Seen after menopause - Women don’t absorb as much calcium so osteoclasts break bone down to release the calcium into the bloodstream 3. Common with compression fractures
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What does bone development and growth look like BEFORE week 8 of life?
Skelton made of hyaline cartilage or mesenchyme
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What does bone development and growth look like AFTER week 8 of life?
Bone tissue begins to replace most cartilage or mesenchyme
How are the scapulae attached to the axial skeleton?
1. Scapulae do NOT join to the axial skeleton at all 2. Their articulation with the clavicle is very loose 3. They are attached to the axial skeleton by way of associated muscles and ligaments 4. This provides a highly flexible system
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Clavicle
1. Appendicular skeleton 2. Located in pectoral girdle 3. "Collarbone" 4. Provides muscle attachment 5. Acts as brace for the scapula and arms 6. S-shape makes it prone to fracturing near the curves
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What does the acromial end of the clavicle attach too?
1. Lateral 2. The acromial end articulates with the acromion process of the scapula
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What does the sternal end of the clavicle attach too?
1. Medial 2. The sternal end attaches to the manubrium of the sternum
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Scapula
1. Appendicular skeleton 2. Located in pectoral girdle 3. Located on the posterior surface of the rib cage 4. Scapular spine is on posterior side of the scapula 5. Contains - Gelnoid cavity - Supraspinous/infraspinous fossae - Subscapular fossa - Coracoid process - Acromion
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Glenoid Cavity
1. AKA glenoid fossa 2. Appendicular skeleton 3. Located in pectoral girdle on scapula 4. Where the humerus articulates 5. Forms shoulder joint
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Supraspinous/infraspinous Fossae
1. Appendicular skeleton 2. Located in pectoral girdle on scapula 3. Attachment sites for muscles
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Subscapular Fossa
1. Appendicular skeleton 2. Located in pectoral girdle on scapula 3. Anterior site for muscle attachment
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Coracoid Process
1. Appendicular skeleton 2. Located in pectoral girdle on scapula 3. Attachment point of the biceps muscle 4. Located anteriorly
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Acromion
1. Appendicular skeleton 2. Located in pectoral girdle on scapula 3. Articulates with the acromial end of clavicle 4. Located posteriorly
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Upper Limb
1. Appendicular skeleton 2. 30 bones 3. Arm 4. Forearm 5. Hand
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Arm
1. AKA Brachium 2. Upper arm 3. One bone - Humerus
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Forearm
1. AKA antebrachium 2. Lower arm 3. Two bones - Radius - Ulna
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Hand
1. Includes the wrist 2. 27 bones - Carpal bones - Metacarpals - Phalanges
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Humerus
1. Appendicular skeleton 2. Found in arm of upper limb 3. Head articulates with scapula at the glenoid cavity 4. Distal end articulates with radius and ulna (elbow) 5. Greater and lesser tubercles are sites of muscle attachment - Deltoid tuberosity is attachment for deltoid muscle 6. Most frequently fractures at the surgical neck
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What are common fractures of the humerus?
1. Surgical neck (1) 2. Midshaft spiral fractures (2) 3. Nerves (in yellow) pass along the bone and can be damaged by these two fractures 4. MAY lead to permanent upper limb dysfunction
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Distal Humerus
1. Appendicular skeleton 2. Found in arm of upper limb 3. Articulates with the radius and ulna 4. Capitulum
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Trochlea (Upper Limb)
1. Appendicular skeleton 2. Found in arm of upper limb 3. Trochlea of the humerus articulates with trochlear notch of ulna 4. Trochlear notch fits over trochlea to create a hinge
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Coronoid (Upper Limb)
1. Appendicular skeleton 2. Found in arm of upper limb 3. Coronoid process of ulna fits into coronoid fossa when forearm bends
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Olecranon Process (Upper Limb)
1. Appendicular skeleton 2. Found in arm of upper limb 3. Olecranon process of ulna fits into the olecranon fossa of the humerus when forearm extends 4. Sharp edge of elbow
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Lateral/Medial Epicondyles (Upper Limb)
1. Appendicular skeleton 2. Found in arm of upper limb 3. Lateral and medial epicondyles on humerus are attachment sites for forearm muscles
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Capitulum
1. Appendicular skeleton 2. Found in arm of upper limb 3. Distal humerus 4. Articulates with head of the radius
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What is the major articulation at the elbow?
Radial head articulates with the radial notch of the ulna (proximal radioulnar joint) to form a pivot joint
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Ulna
1. Appendicular skeleton 2. Found in forearm 3. Medial 4. Connected to the radius by interosseous membrane to keep bones a fixed distance and allow rotation 5. Radial head articulates with radial notch on ulna (proximal) 6. Has a styloid process (distal)
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Radius
1. Appendicular skeleton 2. Found in forearm 3. Lateral 4. Connected to the ulna by interosseous membrane to keep bones a fixed distance and allow rotation 5. Radial head articulates with radial notch on ulna (proximal) 6. Has a styloid process (distal)
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Pronation (Upper Limb)
1. Radius crosses over ulna 2. When palm faces posteriorly - Bones cross and form an X
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Supination (Upper Limb)
1. Radius parallel to ulna 2. In standard anatomical position - Radius is lateral and ulna is medial
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Where do the ligaments that anchor to the wrist attach?
Ligaments that anchor the the wrist attach to the radial and ulnar styloid processes
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Wrist Fractures
1. Typically fracture distal radius while catching yourself during a fall 2. Common in older females 3. “Dinner-fork ” presentation 4. Can lead to nerve damage and dysfunction
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Carpals
1. Appendicular skeleton 2. Found in wrist 3. 8 carpal bones make up wrist 4. Proximal end of hand 5. Arranged (roughly) in 2 rows - Straight Line To Pinky, Here Comes The Thumb 6. Very flexible because of the gliding motions at articulations 7. Scaphoid is fractured most frequently
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Metacarpals
1. Appendicular skeleton 2. Found in hand 3. Each digit has one metacarpal
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Phalanges (Upper Limb)
1. Appendicular skeleton 2. Found in hand 3. Digits II-V have three phalanges - Proximal, middle and distal 4. Digit I (Pollex or Thumb) has two phalanges - Proximal and distal
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How are the digits in the hand labeled?
1. There are 5 digits in each hand 2. They are labeled I-V starting at the thumb and ending at the pinky
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Pelvis
1. Part of both the appendicular and axial skeleton 2. Consists of - Hip bones - Sacrum - Coccyx 3. Attaches the lower limbs to the trunk - Body weight passes through pelvis to the lower limbs 4. Supports viscera 5. Strong attachment to axial skeleton at the sacroiliac joint (very stable) 6. Less freedom of movement compared to pectoral girdle
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Ossa Coxae
1. AKA Hip bones 2. Appendicular skeleton 3. Found in pelvis 4. Consists of three bones that fuse by adulthood - Ilium - Ischium - Pubis
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Acetabulum
1. Appendicular skeleton 2. Where the ilium, ischium, and pubis fuse 3. Found in hipbone in pelvis 4. Cup-shaped lateral socket where head of the femur articulates 5. Composed of all three pelvic bones
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Pubic Symphysis
1. Appendicular skeleton 2. Where the two hip bones articulate (join) anteriorly
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Ilium
1. Appendicular skeleton 2. Hip bone found in pelvis 3. Iliac crest is superior ridge of the bone 4. Greater sciatic notch allows passage of sciatic nerve to lower limb
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Ischium
1. Appendicular skeleton 2. Hip bone found in pelvis 3. Ischial tuberosities are the “sit bones"
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Pubis
1. Appendicular skeleton 2. Hip bone found in pelvis 3. Along with the ischium contributes to obturator foramen