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what is endocrine system
a series of glands which secretes hormones (small chemical molecules spread through the blood stream)
what is pituitary gland
located in brain, produces many hormones, some to body some to other glands
what is thyroid gland
in neck, produces thyroxine which regulates rate of metabolism. pituitary gland releases TSH which stimulates thyroid to produce more thyroxine (negative feedback loop)
what is adrenal gland
below abs, produces adrenaline which increases heart rate and blood pressure
what is pancreas
below and behind stomach, produces insulin which regulates blood glucose concentrations
what is testes
male reproductive, produces testosterone and sperm
what is ovaries
female reproductive, produces oestrogen and egg cells
menstrual cycle
28 days long, first five days called menstruation, day 15 called ovulation
role of oestrogen
stimulates uterus lining to grow after breakdown of lining
role of progesterone
maintains uterus lining
role of LH
stimulates eggs to release on ovulation day
role of FSH
, stimulates eggs to mature in ovaries
overall hormones in mesntrual cycle
FSH stimulates ovaries to produce oestrogen. As oestrogen levels grow, they inhibit FSH, and stimulate LH (ovulation). Progesterone inhibits LH and FSH.
how do hormonal methods of contraception work
release oestrogen and/or progesterone, if oestrogen is produced in excess it inhibits FSH meaning no egg is released. If progesterone is released in excess it stimulates thick mucus in cervix which preents sperm reaching egg
how does IVF work
women are given FSH and LH to stimulate eggs to mature and be released. These are then collected and fertilised in a laboratory. The embryos are placed in an incubator to grow, before being taken out and placed in the mothers uterus.
how can hormones help with infertility
low levels of FSH is a common cause of infertility, so FSH in the form of pills can be given, with LH (to stimulate ovulation). This usually restores fertility.
What is the role of kidneys
Filter blood and remove waste products (mainly urea - made in liver), and regulate levels of ions and water.
how do kidneys regulate water
water gained from food and drinks, and lost through sweat, respiration and urine. Hypothalamus detects low conc. Of water, and signals pituitary gland to release ADH, which tells kidneys to reabsorb more water, so less urine is produced.
how do kidneys regulate filtration
tubules absorb small molecules (everything except proteins and cells), and then nephron reabsorbs useful substances (all glucose, some water, no urea) - SELECTIVE REABSORBTION.
structure of kidneys
Blood enters through Renal Arteries, and out through Renal Veins. Millions of nephrons in kidney. Tubule carries filtered fluid, and blood vessels carry cells, protein, and reabsorbed material. During filtration, the glomerulus passes substances to the Bowmans capsule (and then into the tubule).